BRPI0613303A8 - composições que contêm pufa e/ou uridina e métodos de uso das mesmas - Google Patents
composições que contêm pufa e/ou uridina e métodos de uso das mesmasInfo
- Publication number
- BRPI0613303A8 BRPI0613303A8 BRPI0613303A BRPI0613303A BRPI0613303A8 BR PI0613303 A8 BRPI0613303 A8 BR PI0613303A8 BR PI0613303 A BRPI0613303 A BR PI0613303A BR PI0613303 A BRPI0613303 A BR PI0613303A BR PI0613303 A8 BRPI0613303 A8 BR PI0613303A8
- Authority
- BR
- Brazil
- Prior art keywords
- process streams
- component
- solid material
- open cell
- pufa
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 2
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 title 2
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 title 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 title 1
- 229940045145 uridine Drugs 0.000 title 1
- 238000000926 separation method Methods 0.000 abstract 4
- 230000001413 cellular effect Effects 0.000 abstract 3
- 239000011343 solid material Substances 0.000 abstract 3
- 239000000919 ceramic Substances 0.000 abstract 1
- 238000005229 chemical vapour deposition Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 150000001247 metal acetylides Chemical class 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 150000004767 nitrides Chemical class 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Fertilizers (AREA)
- Separation, Recovery Or Treatment Of Waste Materials Containing Plastics (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68335205P | 2005-05-23 | 2005-05-23 | |
| US71607705P | 2005-09-13 | 2005-09-13 | |
| US75505806P | 2006-01-03 | 2006-01-03 | |
| US76175306P | 2006-01-25 | 2006-01-25 | |
| PCT/US2006/019778 WO2006127627A2 (en) | 2005-05-23 | 2006-05-23 | Compostions containing pufa and/or uridine and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0613303A2 BRPI0613303A2 (pt) | 2009-08-04 |
| BRPI0613303A8 true BRPI0613303A8 (pt) | 2018-01-30 |
Family
ID=37452701
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0613303A BRPI0613303A8 (pt) | 2005-05-23 | 2006-05-23 | composições que contêm pufa e/ou uridina e métodos de uso das mesmas |
| BRPI0613274-0A BRPI0613274A2 (pt) | 2005-05-23 | 2006-05-23 | composições que contêm pufa e métodos de uso das mesmas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0613274-0A BRPI0613274A2 (pt) | 2005-05-23 | 2006-05-23 | composições que contêm pufa e métodos de uso das mesmas |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10086009B2 (enExample) |
| EP (3) | EP3090740A1 (enExample) |
| JP (3) | JP5566603B2 (enExample) |
| CN (1) | CN105663151A (enExample) |
| AU (2) | AU2006251569B2 (enExample) |
| BR (2) | BRPI0613303A8 (enExample) |
| CA (2) | CA2645645C (enExample) |
| DK (1) | DK1888081T3 (enExample) |
| ES (2) | ES2615521T3 (enExample) |
| HU (1) | HUE031206T2 (enExample) |
| NZ (3) | NZ600740A (enExample) |
| PL (1) | PL1888081T3 (enExample) |
| PT (1) | PT1888081T (enExample) |
| RU (1) | RU2603470C2 (enExample) |
| WO (2) | WO2006127620A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070004670A1 (en) * | 1998-07-31 | 2007-01-04 | Richard Wurtman | Compositions containing citicoline, and methods of use thereof |
| US8143234B2 (en) | 1998-07-31 | 2012-03-27 | Massachusetts Institute Of Technology | Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function |
| US8518882B2 (en) * | 1998-07-31 | 2013-08-27 | Massachusetts Institute Of Technology | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same |
| US8314064B2 (en) | 1998-07-31 | 2012-11-20 | Massachusetts Institute Of Technology | Uridine administration stimulates membrane production |
| EP1572115B1 (en) * | 2002-11-27 | 2015-01-21 | Ampio Pharmaceuticals, Inc. | Treatment of diseases and conditions mediated by increased phosphorylation |
| PT1888081T (pt) * | 2005-05-23 | 2017-03-01 | Massachusetts Inst Technology | Composições contendo pufa e seus métodos de utilização |
| MX336435B (es) * | 2005-07-08 | 2016-01-19 | Dsm Ip Assets Bv | Acidos grasos poliinsaturados para el tratamiento de demencia y condiciones relacionadas con pre-demencia. |
| EP1951308B1 (de) * | 2005-11-25 | 2013-02-20 | Gisela Susilo | Kombinationspräparate enthaltend physiologische zellmembran-bestandteile, einschliesslich phosphatidylserin, cholin und ein pyrimidinnukleos/tid |
| CN101636167B (zh) * | 2006-12-28 | 2012-10-03 | 株式会社明治 | 含有乳来源的磷脂的婴幼儿脑发育促进剂以及含有该促进剂的食品组合物 |
| NZ582329A (en) * | 2007-06-26 | 2012-09-28 | Nutricia Nv | Improving memory in subjects with mini-mental state examination of 24-26 |
| WO2009002146A1 (en) | 2007-06-26 | 2008-12-31 | N.V. Nutricia | Supporting activities of daily living |
| WO2009002145A1 (en) | 2007-06-26 | 2008-12-31 | N.V. Nutricia | Lipid composition for improving function of brain functioning |
| WO2009002148A1 (en) * | 2007-06-27 | 2008-12-31 | N.V. Nutricia | Food composition for prodromal dementia patients |
| US8343753B2 (en) | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| WO2009057994A1 (en) | 2007-11-02 | 2009-05-07 | N.V. Nutricia | Unit dosage for brain health |
| WO2009059306A1 (en) * | 2007-11-02 | 2009-05-07 | Massachusetts Institute Of Technology | Uridine dietary supplementation compliance methods and use thereof |
| PL2609812T3 (pl) | 2007-12-20 | 2019-02-28 | N.V. Nutricia | Ciekły produkt zawierający nukleotydy/nukleozydy |
| WO2010088700A1 (en) * | 2009-02-02 | 2010-08-05 | Martek Biosciences Corporation | Methods for improving cognitive function and decreasing heart rate |
| WO2011133580A1 (en) * | 2010-04-19 | 2011-10-27 | Back Bay Scientific Llc | Use of drugs that activate p2y receptors to enhance synaptogenesis |
| WO2012125020A1 (en) | 2011-03-14 | 2012-09-20 | N.V. Nutricia | Method for treating neurotrauma |
| JP2015501426A (ja) * | 2011-10-21 | 2015-01-15 | オムセラ・ファーマシューティカルズ・インコーポレイテッド | 注意欠陥多動障害を処置するまたは予防する方法および組成物 |
| WO2013066152A1 (en) * | 2011-10-31 | 2013-05-10 | N.V. Nutricia | Method for improving executive function |
| BR112014020177A8 (pt) * | 2012-03-02 | 2021-10-19 | Nutricia Nv | Uso de uma composição para a fabricação de um produto para diminuir, prevenir ou reverter a conectividade cerebral funcional prejudicada e/ou organização da rede cerebral prejudicada |
| WO2013129914A1 (en) * | 2012-03-02 | 2013-09-06 | N.V. Nutricia | Method for improving functional synaptic connectivity |
| WO2014171813A1 (en) * | 2013-04-17 | 2014-10-23 | N.V. Nutricia | Nutritional composition for improving brain function in phenylketonuria |
| CN103877144B (zh) * | 2013-05-02 | 2017-02-22 | 杭州耐奇睿生物医药科技有限公司 | 花生衣活性组分的应用及包含该花生衣活性组分的组合物 |
| WO2015138879A1 (en) * | 2014-03-13 | 2015-09-17 | Massachusetts Institute Of Technology | Compositions containing pufa, uridine and choline and methods of use thereof |
| WO2016083362A1 (en) * | 2014-11-25 | 2016-06-02 | Fonden For Helene Elsass Centeret | Composition for improving cognitive functions |
| WO2017069613A1 (en) | 2015-10-23 | 2017-04-27 | N.V. Nutricia | Method for improving recognition and/or working memory in hyperphenylalanimenia and phenylketonuria patients |
| WO2017155387A1 (en) | 2016-03-08 | 2017-09-14 | N.V. Nutricia | Method for supporting memory function and/or cognitive function |
| WO2017167415A1 (en) * | 2016-03-30 | 2017-10-05 | Nestec S.A. | Compositions comprising fatty acids and their use |
| JP2019518798A (ja) * | 2016-06-27 | 2019-07-04 | オハイオ・ステイト・イノベーション・ファウンデーション | リポヌクレオチドに基づくardsの治療 |
| EP3518919A1 (en) * | 2016-09-29 | 2019-08-07 | Société des Produits Nestlé S.A. | Omega 3 fatty acids and choline as neuroprotectant in patients with no dementia |
| US20210077446A1 (en) * | 2016-12-13 | 2021-03-18 | Dsm Ip Assets B.V. | Pufa salt formulations (ii) |
| WO2021231566A1 (en) * | 2020-05-12 | 2021-11-18 | Massachusetts Institute Of Technology | The use of choline supplementation as therapy for apoe4-related disorders |
| EP4190319A4 (en) | 2020-07-29 | 2024-05-01 | Novamedica Limited Liability Company | PHARMACEUTICAL COMPOSITION CONTAINING MEMANTINE AND CITICOLINE |
| WO2022258873A1 (es) * | 2021-06-09 | 2022-12-15 | Hospital Sant Joan De Deu | Combinación nutracéutica y su uso para el tratamiento de trastornos neurológicos |
| CN113577092B (zh) * | 2021-07-30 | 2022-07-01 | 陈玉松 | 一种延缓衰老的含核苷酸的组合物及其制备方法和应用 |
| CN115774059A (zh) * | 2021-09-07 | 2023-03-10 | 中国科学院深圳先进技术研究院 | 一种阿尔兹海默症生物标志物及其筛选方法和应用 |
| TR2021016704A2 (tr) * | 2021-10-26 | 2021-11-22 | Bursa Uludag Ueniversitesi | Üri̇di̇ni̇n ön uyaran aracili i̇nhi̇bi̇syon bozukluğu i̇le seyreden hastaliklarin tedavi̇si̇nde kullanimi |
| WO2023150389A1 (en) * | 2022-02-07 | 2023-08-10 | Cornell University | Compositions and methods for increasing dha availability |
| CN115334384B (zh) | 2022-08-05 | 2025-03-14 | 立臻科技(昆山)有限公司 | 一种移动终端会议音箱 |
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| US7951410B2 (en) * | 2003-04-14 | 2011-05-31 | Mead Johnson Nutrition Company | Enteral compositions containing caseinoglycomacropeptide having an enhanced concentration of sialic acid |
| EP1670324A1 (en) | 2003-09-26 | 2006-06-21 | Nestec S.A. | Nutritional composition with unsaturated fatty acids and trace elements |
| US8921422B2 (en) | 2003-10-01 | 2014-12-30 | The Iams Company | Methods and kits for enhancing ability to learn in a puppy or kitten |
| AU2004317087A1 (en) | 2003-10-08 | 2005-09-22 | The Mclean Hospital Corporation | Methods of treating psychiatric, substance abuse, and other disorders using combinations containing omega-3 fatty acids |
| EP1634599A1 (en) | 2004-08-20 | 2006-03-15 | N.V. Nutricia | Iimmune stimulatory infant nutrition |
| EP1656839A1 (en) | 2004-11-11 | 2006-05-17 | N.V. Nutricia | Nutrition containing lipid blend |
| US20060247153A1 (en) | 2005-04-29 | 2006-11-02 | Mcmahon Robert J | Method of improving learning and memory in mammals |
| PT1888081T (pt) * | 2005-05-23 | 2017-03-01 | Massachusetts Inst Technology | Composições contendo pufa e seus métodos de utilização |
| US7829126B2 (en) | 2005-10-26 | 2010-11-09 | Abbott Laboratories | Infant formulas containing docosahexaenoic acid and lutein |
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2006
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- 2006-05-23 CA CA2645645A patent/CA2645645C/en active Active
- 2006-05-23 EP EP16171448.0A patent/EP3090740A1/en not_active Withdrawn
- 2006-05-23 JP JP2008513592A patent/JP5566603B2/ja active Active
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