BRPI0609636A2 - formulações farmacêuticas - Google Patents

formulações farmacêuticas

Info

Publication number
BRPI0609636A2
BRPI0609636A2 BRPI0609636-0A BRPI0609636A BRPI0609636A2 BR PI0609636 A2 BRPI0609636 A2 BR PI0609636A2 BR PI0609636 A BRPI0609636 A BR PI0609636A BR PI0609636 A2 BRPI0609636 A2 BR PI0609636A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical formulations
chlorobenzoyl
phenoxy
methylpropanoic acid
acid
Prior art date
Application number
BRPI0609636-0A
Other languages
English (en)
Inventor
Tong Zhu
Tzuchi R Ju
Claudia M Davila
Kevin R Engh
Yi Gao
Linda E Gustavson
Shyamala C Jayaraman
David Leblond
Dennis Y Lee
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0609636A2 publication Critical patent/BRPI0609636A2/pt
Publication of BRPI0609636B1 publication Critical patent/BRPI0609636B1/pt
Publication of BRPI0609636B8 publication Critical patent/BRPI0609636B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

FORMULAçõES FARMACêUTICAS: A presente invenção diz respeito às tormulações orais que compreendem um agente ativo compreendendo pelo menos um de ácido 2-[4- (4-clorobenzoil) fenóxi]-2-metil-propanóico, sais de ácido 2-4-(4-clorobenzoil) fenóxi]-2-metil-propanóico ou ácido 2-[4-(4-clorobenzoil) fenóxi]-2-metil-propanóico tamponado.
BRPI0609636A 2005-04-08 2006-04-07 formulação oral de liberação modificada que compreende um agente ativo e um revestimento entérico BRPI0609636B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66969905P 2005-04-08 2005-04-08
US60/669,699 2005-04-08
PCT/US2006/013121 WO2006135480A2 (en) 2005-04-08 2006-04-07 Oral pharmaceutical formulations comprising fenofibric acid and/or its salts

Publications (3)

Publication Number Publication Date
BRPI0609636A2 true BRPI0609636A2 (pt) 2009-09-29
BRPI0609636B1 BRPI0609636B1 (pt) 2020-12-29
BRPI0609636B8 BRPI0609636B8 (pt) 2021-05-25

Family

ID=37246305

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0609636A BRPI0609636B8 (pt) 2005-04-08 2006-04-07 formulação oral de liberação modificada que compreende um agente ativo e um revestimento entérico

Country Status (17)

Country Link
US (4) US20060280791A1 (pt)
EP (2) EP1868587A2 (pt)
JP (1) JP5114382B2 (pt)
KR (1) KR20080008352A (pt)
CN (2) CN102172347A (pt)
AU (1) AU2006258217A1 (pt)
BR (1) BRPI0609636B8 (pt)
CA (1) CA2604078C (pt)
EA (1) EA023376B1 (pt)
ES (1) ES2545589T3 (pt)
HK (1) HK1131918A1 (pt)
IL (1) IL186435A (pt)
MX (1) MX2007012443A (pt)
NO (1) NO343548B1 (pt)
SG (1) SG161256A1 (pt)
UA (1) UA100966C2 (pt)
WO (1) WO2006135480A2 (pt)

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UA92920C2 (ru) * 2005-10-31 2010-12-27 Кова Ко., Лтд. Таблетка с насечкой, включающая питавастатин, и имеющая превосходную фотостабильность
US7569612B1 (en) * 2006-08-21 2009-08-04 Mutual Pharmaceutical Company, Inc. Methods of use of fenofibric acid
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MX2011007172A (es) * 2009-01-02 2011-08-04 Fournier Lab Ireland Ltd Uso novedoso de fibratos.
WO2010131265A1 (en) * 2009-05-11 2010-11-18 Lupin Limited Novel pharmaceutical compositions of choline fenofibrate
EP2521537A2 (en) * 2010-01-04 2012-11-14 Wockhardt Limited Pharmaceutical composition for modified delivery of actives
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CN102058544B (zh) * 2010-12-10 2012-10-03 山东省医药工业研究所 非诺贝特酸胆碱盐肠溶缓释微丸的制备方法
CN102757338B (zh) * 2012-02-29 2015-02-25 郑州泰基鸿诺药物科技有限公司 一种非诺贝特酸氨基酸乙酯盐、制备方法及其用途
EP2958548A1 (en) * 2013-02-19 2015-12-30 Sanovel Ilac Sanayi ve Ticaret A.S. A production process for gliclazide formulations
CN104758293A (zh) * 2014-01-02 2015-07-08 江苏吉贝尔药业有限公司 一种新的复方抗高血压制剂的制备方法
CN105748445A (zh) * 2016-03-31 2016-07-13 武汉药谷生物工程有限公司 一种非诺贝酸胆碱缓释胶囊的制备方法
CN107496397A (zh) * 2016-06-14 2017-12-22 重庆安格龙翔医药科技有限公司 一种二甲双胍与非诺贝酸的复合物及其制剂
CN110996915B (zh) * 2017-08-09 2023-10-03 阿尔比里奥公司 考来烯胺丸粒、口服考来烯胺制剂及其用途
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Also Published As

Publication number Publication date
IL186435A (en) 2015-09-24
US20070128278A1 (en) 2007-06-07
WO2006135480A2 (en) 2006-12-21
SG161256A1 (en) 2010-05-27
UA100966C2 (ru) 2013-02-25
ES2545589T3 (es) 2015-09-14
EA023376B1 (ru) 2016-05-31
JP2008535851A (ja) 2008-09-04
WO2006135480A9 (en) 2007-02-15
CN102172347A (zh) 2011-09-07
JP5114382B2 (ja) 2013-01-09
BRPI0609636B8 (pt) 2021-05-25
US20060280791A1 (en) 2006-12-14
NO343548B1 (no) 2019-04-01
NO20075628L (no) 2007-11-05
EA200702198A1 (ru) 2008-04-28
BRPI0609636B1 (pt) 2020-12-29
WO2006135480A3 (en) 2007-04-05
CA2604078A1 (en) 2006-12-21
CA2604078C (en) 2013-07-23
US20070264334A1 (en) 2007-11-15
EP1868587A2 (en) 2007-12-26
EP2074992A1 (en) 2009-07-01
MX2007012443A (es) 2007-12-13
HK1131918A1 (en) 2010-02-12
US20060280790A1 (en) 2006-12-14
CN101217944A (zh) 2008-07-09
IL186435A0 (en) 2008-01-20
EP2074992B1 (en) 2015-05-20
KR20080008352A (ko) 2008-01-23
AU2006258217A1 (en) 2006-12-21

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