BRPI0517916A - comprimido que compreende um sal de carbonato de um polìmero de amina alifática, composições e método para remover fosfato de um paciente com necessidade do mesmo - Google Patents

comprimido que compreende um sal de carbonato de um polìmero de amina alifática, composições e método para remover fosfato de um paciente com necessidade do mesmo

Info

Publication number
BRPI0517916A
BRPI0517916A BRPI0517916-5A BRPI0517916A BRPI0517916A BR PI0517916 A BRPI0517916 A BR PI0517916A BR PI0517916 A BRPI0517916 A BR PI0517916A BR PI0517916 A BRPI0517916 A BR PI0517916A
Authority
BR
Brazil
Prior art keywords
compositions
need
aliphatic amine
amine polymer
tablet
Prior art date
Application number
BRPI0517916-5A
Other languages
English (en)
Inventor
Hitesh R Bhagat
Jeffrey Marc Goldberg
Abizer Harianawala
Louis Brenner
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36120243&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0517916(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of BRPI0517916A publication Critical patent/BRPI0517916A/pt
Publication of BRPI0517916B1 publication Critical patent/BRPI0517916B1/pt
Publication of BRPI0517916B8 publication Critical patent/BRPI0517916B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Abstract

COMPRIMIDO QUE COMPREENDE UM SAL DE CARBONATO DE UM POLìMERO DE AMINA ALIFATICA, COMPOSIçõES E MéTODO PARA REMOVER FOSFATO DE UM PACIENTE COM NECESSIDADE DO MESMO. Os comprimidos, composições e métodos da presente invenção, que compreende um sal de carbonato de um polímero de amina alifática e ânion monovalente pode evitar ou melhorar acidose, em particular acidose em pacientes com enfermidade renal. Os comprimidos e composições da presente invenção mantêm um tempo de desintegração não maior do que 30 minutos a 37 C e sob um pH de pelo menos 1 durante um período de pelo menos dez semanas a 60 C. Além disso, os comprimidos são estáveis durante períodos de tempo prolongados sem a necessidade de condições de armazenamento especializadas.
BRPI0517916A 2004-11-01 2005-11-01 comprimido compreendendo carbonato de sevelamer e cloreto de sódio, e, uso de um comprimido BRPI0517916B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62400104P 2004-11-01 2004-11-01
US62875204P 2004-11-17 2004-11-17
PCT/US2005/039366 WO2006050315A2 (en) 2004-11-01 2005-11-01 Aliphatic amine polymer salts for tableting

Publications (3)

Publication Number Publication Date
BRPI0517916A true BRPI0517916A (pt) 2008-10-21
BRPI0517916B1 BRPI0517916B1 (pt) 2018-11-27
BRPI0517916B8 BRPI0517916B8 (pt) 2019-05-21

Family

ID=36120243

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517916A BRPI0517916B8 (pt) 2004-11-01 2005-11-01 comprimido compreendendo carbonato de sevelamer e cloreto de sódio, e, uso de um comprimido

Country Status (18)

Country Link
US (4) US7985418B2 (pt)
EP (2) EP1807057B1 (pt)
JP (2) JP5307398B2 (pt)
CN (2) CN102824322A (pt)
AU (1) AU2005302243B2 (pt)
BR (1) BRPI0517916B8 (pt)
CA (2) CA2586023C (pt)
CY (1) CY1119155T1 (pt)
DK (1) DK1807057T3 (pt)
ES (2) ES2716982T3 (pt)
HK (1) HK1113543A1 (pt)
HR (1) HRP20170505T1 (pt)
HU (1) HUE033638T2 (pt)
LT (1) LT1807057T (pt)
MX (1) MX2007004939A (pt)
PL (1) PL1807057T3 (pt)
PT (1) PT1807057T (pt)
WO (1) WO2006050315A2 (pt)

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