BRPI0515850A - agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos - Google Patents

agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos

Info

Publication number
BRPI0515850A
BRPI0515850A BRPI0515850-8A BRPI0515850A BRPI0515850A BR PI0515850 A BRPI0515850 A BR PI0515850A BR PI0515850 A BRPI0515850 A BR PI0515850A BR PI0515850 A BRPI0515850 A BR PI0515850A
Authority
BR
Brazil
Prior art keywords
methods
cupredoxin
transport agents
agents derived
derived
Prior art date
Application number
BRPI0515850-8A
Other languages
English (en)
Inventor
Ananda Chakrabarty
Tapas Das Gupta
Tohru Yamada
Arsenio Fialho
Original Assignee
Ananda Chakrabarty
Tapas Das Gupta
Tohru Yamada
Arsenio Fialho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ananda Chakrabarty, Tapas Das Gupta, Tohru Yamada, Arsenio Fialho filed Critical Ananda Chakrabarty
Publication of BRPI0515850A publication Critical patent/BRPI0515850A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/221—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by the targeting agent or modifying agent linked to the acoustically-active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

"AGENTES DE TRANSPORTE DERIVADOS DE CUPREDOXINA E MéTODOS DE USO DOS MESMOS". Onde são descritos métodos e materiais para aplicação de um composto de carga em uma célula de câncer; como também a aplicação do composto de carga é realizada pelo uso dos domínios de transdução de proteína derivados de cupredoxinas; incluindo-se aindak, adicionalmente, métodos para o tratamento do câncer e o diagnóstico do câncer.
BRPI0515850-8A 2004-10-07 2005-10-06 agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos BRPI0515850A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61678204P 2004-10-07 2004-10-07
US68050005P 2005-05-13 2005-05-13
US70029705P 2005-07-19 2005-07-19
PCT/US2005/035758 WO2006088508A2 (en) 2004-10-07 2005-10-06 Cupredoxin derived transport agents and methods of use thereof

Publications (1)

Publication Number Publication Date
BRPI0515850A true BRPI0515850A (pt) 2008-08-12

Family

ID=36916885

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0515850-8A BRPI0515850A (pt) 2004-10-07 2005-10-06 agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos

Country Status (17)

Country Link
US (5) US7691383B2 (pt)
EP (1) EP1797114A4 (pt)
JP (2) JP2008515428A (pt)
KR (1) KR20070108128A (pt)
CN (1) CN101437842A (pt)
AP (1) AP2007003959A0 (pt)
AU (1) AU2005327535A1 (pt)
BR (1) BRPI0515850A (pt)
CA (1) CA2582164A1 (pt)
CR (1) CR9033A (pt)
EA (1) EA200700813A1 (pt)
IL (1) IL182202A0 (pt)
NO (1) NO20072355L (pt)
TN (1) TNSN07113A1 (pt)
UA (1) UA97466C2 (pt)
WO (1) WO2006088508A2 (pt)
ZA (1) ZA200702855B (pt)

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AU2005327535A1 (en) 2004-10-07 2006-08-24 Ananda Chakrabarty Cupredoxin derived transport agents and methods of use thereof
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US10675326B2 (en) 2004-10-07 2020-06-09 The Board Of Trustees Of The University Of Illinois Compositions comprising cupredoxins for treating cancer
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AU2006284490A1 (en) * 2005-07-19 2007-03-01 The Board Of Trustees Of The University Of Illinois Compositions and methods to control angiogenesis with cupredoxins
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BRPI0714987A2 (pt) * 2006-09-14 2013-07-30 Trutees Of The University Of Illinoi Board Of composiÇÕes e mÉtodos para a prevenÇço do cÂncer com cupredoxina
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BRPI0714987A2 (pt) 2006-09-14 2013-07-30 Trutees Of The University Of Illinoi Board Of composiÇÕes e mÉtodos para a prevenÇço do cÂncer com cupredoxina
RU2009125599A (ru) * 2006-12-04 2011-01-20 Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Иллинойс (Us) Композиции и способы лечения рака cpg-богатой днк и купредоксинами
CN101668536A (zh) 2007-02-08 2010-03-10 伊利诺斯大学理事会 用铜氧还蛋白预防癌症的组合物和方法
WO2009078977A2 (en) 2007-12-14 2009-06-25 Cdg Therapeutics Inc Compositions and methods to concurrently treat or prevent multiple diseases with cupredoxins

Also Published As

Publication number Publication date
EP1797114A4 (en) 2009-07-15
JP2014204720A (ja) 2014-10-30
US8530635B2 (en) 2013-09-10
US7691383B2 (en) 2010-04-06
US20100209355A1 (en) 2010-08-19
WO2006088508A2 (en) 2006-08-24
UA97466C2 (ru) 2012-02-27
AP2007003959A0 (en) 2007-04-30
IL182202A0 (en) 2007-07-24
US10239920B2 (en) 2019-03-26
TNSN07113A1 (en) 2008-06-02
CR9033A (es) 2010-04-08
KR20070108128A (ko) 2007-11-08
CN101437842A (zh) 2009-05-20
US9161989B2 (en) 2015-10-20
AU2005327535A1 (en) 2006-08-24
US8206685B2 (en) 2012-06-26
ZA200702855B (en) 2008-10-29
US20140037554A1 (en) 2014-02-06
JP2008515428A (ja) 2008-05-15
NO20072355L (no) 2007-07-04
CA2582164A1 (en) 2006-08-24
EA200700813A1 (ru) 2008-10-30
US20060149037A1 (en) 2006-07-06
WO2006088508A3 (en) 2008-12-24
EP1797114A2 (en) 2007-06-20
US20130011338A1 (en) 2013-01-10
US20160031947A1 (en) 2016-02-04

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