BRPI0510500A - composições farmacêuticas - Google Patents

composições farmacêuticas

Info

Publication number
BRPI0510500A
BRPI0510500A BRPI0510500-5A BRPI0510500A BRPI0510500A BR PI0510500 A BRPI0510500 A BR PI0510500A BR PI0510500 A BRPI0510500 A BR PI0510500A BR PI0510500 A BRPI0510500 A BR PI0510500A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
compositions
relates
present
glycopyrrolate
Prior art date
Application number
BRPI0510500-5A
Other languages
English (en)
Inventor
David Morton
Martin Shott
Rebecca Davies
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32408337&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0510500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vectura Ltd filed Critical Vectura Ltd
Publication of BRPI0510500A publication Critical patent/BRPI0510500A/pt
Publication of BRPI0510500B1 publication Critical patent/BRPI0510500B1/pt
Publication of BRPI0510500B8 publication Critical patent/BRPI0510500B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS. A presente invenção refere-se a composições farmacêuticas que compreendem o agente antimuscarínico glicopirrolato, por exemplo, o sal brometo de glicopirrónio. Em particular, a presente invenção refere-se a composições em pó seco que exibem estabilidade aperfeiçoada com o tempo, e a métodos para produzir essas composições.
BRPI0510500A 2004-04-30 2005-04-29 formulação de pó seco, seu método de preparação e dispositivo de inalação de pó seco BRPI0510500B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0409703.6A GB0409703D0 (en) 2004-04-30 2004-04-30 Pharmaceutical compositions
GB0409703.6 2004-04-30
PCT/EP2005/051980 WO2005105043A2 (en) 2004-04-30 2005-04-29 Pharmaceutical compositions

Publications (3)

Publication Number Publication Date
BRPI0510500A true BRPI0510500A (pt) 2007-10-30
BRPI0510500B1 BRPI0510500B1 (pt) 2019-04-24
BRPI0510500B8 BRPI0510500B8 (pt) 2021-05-25

Family

ID=32408337

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510500A BRPI0510500B8 (pt) 2004-04-30 2005-04-29 formulação de pó seco, seu método de preparação e dispositivo de inalação de pó seco

Country Status (27)

Country Link
US (1) US20080063719A1 (pt)
EP (3) EP1755555B1 (pt)
JP (2) JP5000483B2 (pt)
KR (1) KR101287919B1 (pt)
CN (3) CN102008453A (pt)
AU (2) AU2005237266B2 (pt)
BR (1) BRPI0510500B8 (pt)
CA (1) CA2563760C (pt)
CY (6) CY1113069T1 (pt)
DK (2) DK1755555T3 (pt)
ES (2) ES2546982T3 (pt)
GB (1) GB0409703D0 (pt)
HK (2) HK1095282A1 (pt)
HU (4) HUE025463T2 (pt)
IL (2) IL178651A (pt)
LT (1) LTC2422766I2 (pt)
LU (2) LU92176I2 (pt)
MX (2) MXPA06012493A (pt)
NO (1) NO20065502L (pt)
NZ (1) NZ550479A (pt)
PL (2) PL2422766T3 (pt)
PT (2) PT1755555E (pt)
RU (1) RU2396943C2 (pt)
SG (3) SG186673A1 (pt)
SI (2) SI2422766T1 (pt)
WO (1) WO2005105043A2 (pt)
ZA (1) ZA200609350B (pt)

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PL2229148T3 (pl) * 2007-12-13 2014-08-29 Novartis Ag Sposób otrzymywania krystalicznych cząstek stałych substancji leczniczej
EP3311820A1 (en) * 2008-02-26 2018-04-25 Sunovion Respiratory Development Inc. Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
US20100055045A1 (en) 2008-02-26 2010-03-04 William Gerhart Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
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AU2010238641A1 (en) * 2009-04-24 2011-11-10 Merck Sharp & Dohme Corp. Agglomerate formulations useful in dry powder inhalers
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
GB0921481D0 (en) * 2009-12-08 2010-01-20 Vectura Ltd Process and product
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CA2794941C (en) 2010-04-01 2018-05-15 Chiesi Farmaceutici S.P.A. Process for preparing carrier particles for dry powders for inhalation
SI2560611T1 (en) 2010-04-21 2018-03-30 Chiesi Farmaceutici S.P.A. A process for preparing particles with reduced electrostatic charges
JP5792307B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドGlaxo Group Limited 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
JP5792308B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドGlaxo Group Limited 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
JO3510B1 (ar) 2011-03-04 2020-07-05 Heptares Therapeutics Ltd استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب
JP6267685B2 (ja) 2012-04-13 2018-01-24 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 集合粒子
AU2013100007B4 (en) * 2013-01-04 2013-05-23 Novartis Ag System for treating chronic obstructive pulmonary disease
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
CA2902795C (en) 2013-02-28 2021-06-15 Dermira, Inc. Glycopyrrolate salts
KR102391332B1 (ko) 2013-03-15 2022-04-26 펄 테라퓨틱스 인코포레이티드 미립자 결정질 재료를 컨디셔닝하는 방법 및 시스템
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
GB201402556D0 (en) 2014-02-13 2014-04-02 Crystec Ltd Improvements relating to inhalable particles
TN2017000077A1 (en) 2014-09-09 2018-07-04 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
AR102305A1 (es) 2014-10-16 2017-02-15 Teva Branded Pharmaceutical Products R&D Inc Procedimiento para preparar formulación farmacéutica inhalable de polvo seco
US9925168B2 (en) 2016-01-22 2018-03-27 Chiesi Farmaceutici S.P.A. Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation
CA3016488C (en) 2016-03-08 2023-04-11 Mereo Biopharma 1 Limited Dosage regimen for the treatment of acute exacerbations of chronic obstructive pulmonary disease
JP6741773B2 (ja) 2016-03-08 2020-08-19 メレオ バイオファーマ 1 リミテッド 炎症状態の急性増悪の治療のための投与レジメン
ES2805434T3 (es) 2016-07-29 2021-02-12 Inke Sa Procedimiento de estabilización de tamaño de partícula
US11219602B2 (en) 2017-03-15 2022-01-11 Vectura Limited Method for making a micronized dry powder formulation of glycopyrrolate and magnesium stearate
WO2019060595A1 (en) 2017-09-20 2019-03-28 Teva Branded Pharmaceutical Products R&D, Inc. INHALABLE DRY POWDER MEDICINAL PRODUCT COMPRISING GLYCOPYRRONIUM
WO2019060604A1 (en) * 2017-09-20 2019-03-28 Teva Branded Pharmaceutical Products R&D, Inc. INHALABLE MEDICINE
JP7280627B2 (ja) 2017-12-11 2023-05-24 メレオ バイオファーマ 1 リミテッド 慢性閉塞性肺疾患の急性増悪の処置における3-[5-アミノ-4-(3-シアノベンゾイル)-ピラゾール-1-イル]-n-シクロプロピル-4-メチルベンズアミドの使用
HUE054266T2 (hu) 2017-12-11 2021-08-30 Mereo Biopharma 1 Ltd 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-N-ciklopropil-4-metilbenzamid alkalmazása krónikus obstruktív tüdõbetegség akut megjelenésének megelõzésében
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Also Published As

Publication number Publication date
BRPI0510500B1 (pt) 2019-04-24
CY2013012I1 (el) 2015-08-05
RU2006142322A (ru) 2008-06-20
EP1755555B1 (en) 2012-05-23
CN102008453A (zh) 2011-04-13
HUE025463T2 (en) 2016-02-29
CN1964700A (zh) 2007-05-16
SI1755555T1 (sl) 2012-10-30
US20080063719A1 (en) 2008-03-13
ES2388289T3 (es) 2012-10-11
EP2422766A2 (en) 2012-02-29
EP2422767A3 (en) 2012-04-25
CY2014015I2 (el) 2015-12-09
PT2422766E (pt) 2015-10-12
CY2014015I1 (el) 2015-12-09
PL1755555T3 (pl) 2012-11-30
DK1755555T3 (da) 2012-08-20
HUS1500072I1 (hu) 2016-02-29
CY2015060I1 (el) 2020-05-29
WO2005105043A2 (en) 2005-11-10
MX341426B (es) 2016-08-18
LU92392I2 (fr) 2015-11-02
EP2422767A2 (en) 2012-02-29
HUS1300006I1 (hu) 2016-07-28
SI2422766T1 (sl) 2015-10-30
CA2563760A1 (en) 2005-11-10
IL178651A (en) 2012-12-31
LU92176I2 (fr) 2013-05-27
AU2005237266A1 (en) 2005-11-10
CY2013012I2 (el) 2015-08-05
SG152292A1 (en) 2009-05-29
JP5000483B2 (ja) 2012-08-15
BRPI0510500B8 (pt) 2021-05-25
EP2422766B1 (en) 2015-06-24
IL178651A0 (en) 2007-02-11
CA2563760C (en) 2013-07-02
IL223545A0 (en) 2013-02-03
ES2546982T3 (es) 2015-09-30
AU2005237266B2 (en) 2010-11-11
HUS1500073I1 (hu) 2016-02-29
NO20065502L (no) 2007-01-24
RU2396943C2 (ru) 2010-08-20
AU2011200543A1 (en) 2011-03-03
EP2422766A3 (en) 2012-04-25
NZ550479A (en) 2009-11-27
WO2005105043A3 (en) 2006-05-04
SG10201605001SA (en) 2016-08-30
CN107252423A (zh) 2017-10-17
IL223545A (en) 2016-04-21
DK2422766T3 (da) 2015-08-31
KR101287919B1 (ko) 2013-07-18
HK1095282A1 (en) 2007-05-04
PL2422766T3 (pl) 2015-11-30
LTC2422766I2 (lt) 2020-02-10
MXPA06012493A (es) 2007-01-29
CY2015059I1 (el) 2020-05-29
AU2011200543B2 (en) 2012-11-29
JP2007535522A (ja) 2007-12-06
ZA200609350B (en) 2008-04-30
SG186673A1 (en) 2013-01-30
HK1167334A1 (en) 2012-11-30
CY1116655T1 (el) 2017-03-15
LU92176I9 (pt) 2019-01-04
KR20070033978A (ko) 2007-03-27
GB0409703D0 (en) 2004-06-02
AU2011200543A8 (en) 2011-03-31
JP2012031209A (ja) 2012-02-16
CY1113069T1 (el) 2015-08-05
PT1755555E (pt) 2012-08-17
JP5124718B2 (ja) 2013-01-23
EP1755555A2 (en) 2007-02-28

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