BRPI0414778A - 6-aril-7-halo-imidazo[1,2-a]pirimidinas como agentes anticáncer - Google Patents
6-aril-7-halo-imidazo[1,2-a]pirimidinas como agentes anticáncerInfo
- Publication number
- BRPI0414778A BRPI0414778A BRPI0414778-2A BRPI0414778A BRPI0414778A BR PI0414778 A BRPI0414778 A BR PI0414778A BR PI0414778 A BRPI0414778 A BR PI0414778A BR PI0414778 A BRPI0414778 A BR PI0414778A
- Authority
- BR
- Brazil
- Prior art keywords
- imidazo
- halo
- aryl
- pyrimidines
- anticancer agents
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50548603P | 2003-09-24 | 2003-09-24 | |
| PCT/US2004/030595 WO2005030218A1 (en) | 2003-09-24 | 2004-09-17 | 6-aryl-7-halo-imidazo[1,2-a]pyrimidines as anticancer agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0414778A true BRPI0414778A (pt) | 2006-11-21 |
Family
ID=34393021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0414778-2A BRPI0414778A (pt) | 2003-09-24 | 2004-09-17 | 6-aril-7-halo-imidazo[1,2-a]pirimidinas como agentes anticáncer |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7285555B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1684763B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4695595B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN100486580C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE398452T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2004275728A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0414778A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2537520A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE602004014525D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1684763T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2308256T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA06002939A (cg-RX-API-DMAC7.html) |
| PL (1) | PL1684763T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005030218A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2302391T3 (es) * | 1998-12-18 | 2008-07-01 | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT COMPANY, LTD. | Procedimiento de administracion de un compuesto a celulas resistentes a multi-farmacos. |
| DK2495016T3 (da) | 2005-12-23 | 2019-12-16 | Ariad Pharma Inc | Bicykliske heteroarylforbindelser |
| CN101600350A (zh) * | 2007-01-08 | 2009-12-09 | 巴斯夫欧洲公司 | 唑并嘧啶在防治植物病原性有害真菌中的用途 |
| CN107935870A (zh) * | 2017-11-09 | 2018-04-20 | 华中药业股份有限公司 | 一种2‑甲氨基‑5‑氯二苯甲酮的合成方法 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593996A (en) * | 1991-12-30 | 1997-01-14 | American Cyanamid Company | Triazolopyrimidine derivatives |
| TW224044B (cg-RX-API-DMAC7.html) | 1991-12-30 | 1994-05-21 | Shell Internat Res Schappej B V | |
| JP2794510B2 (ja) | 1992-03-27 | 1998-09-10 | 富士写真フイルム株式会社 | ハロゲン化銀写真感光材料 |
| IL108747A (en) | 1993-03-04 | 1999-03-12 | Shell Int Research | Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation |
| TW258648B (cg-RX-API-DMAC7.html) | 1993-03-04 | 1995-10-01 | Shell Internat Res Schappej Bv | |
| RU2147584C1 (ru) | 1995-10-27 | 2000-04-20 | Американ Цианамид Компани | Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов |
| US5817663A (en) | 1996-10-07 | 1998-10-06 | American Cyanamid Company | Pentafluorophenylazolopyrimidines |
| DK0984919T3 (da) | 1997-03-18 | 2003-05-12 | Basf Ag | Fremgangsmåde til fremstilling af arylmalonater |
| US5750766A (en) | 1997-03-18 | 1998-05-12 | American Cyanamid Company | Process for the preparation of arylmalonates |
| US5948783A (en) | 1997-04-14 | 1999-09-07 | American Cyanamid Company | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| US6117876A (en) | 1997-04-14 | 2000-09-12 | American Cyanamid Company | Fungicidal trifluorophenyl-triazolopyrimidines |
| US6255309B1 (en) | 1999-03-19 | 2001-07-03 | American Cyanomid Co. | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| TWI252231B (en) | 1997-04-14 | 2006-04-01 | American Cyanamid Co | Fungicidal trifluorophenyl-triazolopyrimidines |
| TW460476B (en) | 1997-04-14 | 2001-10-21 | American Cyanamid Co | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| US5994360A (en) | 1997-07-14 | 1999-11-30 | American Cyanamid Company | Fungicidal 5-alkyl-triazolopyrimidines |
| CZ292964B6 (cs) | 1998-02-11 | 2004-01-14 | Wyeth Holdings Corporation | Triazolopyrimidiny, způsob jejich přípravy, fungicidní kompozice s jejich obsahem, způsob potírání hub a použití |
| US6020338A (en) | 1998-02-11 | 2000-02-01 | American Cyanamid Company | Fungicidal 7-alkyl-triazolopyrimidines |
| JPH11322517A (ja) | 1998-03-17 | 1999-11-24 | American Cyanamid Co | トリアゾロピリミジン類の効力の増進 |
| US6124301A (en) | 1998-03-17 | 2000-09-26 | American Cyanamid Company | Enhancement of the efficacy of triazolopyrimidines |
| US6284762B1 (en) | 1998-03-23 | 2001-09-04 | American Cyanamid Company | Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines |
| ATE299505T1 (de) | 1998-03-23 | 2005-07-15 | Basf Ag | Fungizide 6-(2-halo-4-alkoxyphenyl)- triazolopyrimidine |
| US5981534A (en) | 1998-09-25 | 1999-11-09 | American Cyanamid Company | Fungicidal 6-(2,6-difluoro-4-alkoxyphenyl)-triazolopyrimidines |
| US6117865A (en) | 1998-09-10 | 2000-09-12 | American Cyanamid Company | Fungicidal trifluorophenyl-triazolopyrimidines |
| US6268371B1 (en) | 1998-09-10 | 2001-07-31 | American Cyanamid Co. | Fungicidal mixtures |
| US5986135A (en) | 1998-09-25 | 1999-11-16 | American Cyanamid Company | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| US6156925A (en) | 1998-09-25 | 2000-12-05 | American Cyanamid Company | Process for the preparation of halogenated phenylmaloates |
| HUP0103741A3 (en) | 1998-09-25 | 2004-09-28 | Basf Ag | Non-aqueous suspension concentrate |
| US6277856B1 (en) | 1998-09-25 | 2001-08-21 | American Cynamid Co. | Fungicidal mixtures |
| JP2000103790A (ja) | 1998-09-25 | 2000-04-11 | American Cyanamid Co | 殺菌・殺カビ性のトリハロフェニル―トリアゾロピリミジン類 |
| US6242451B1 (en) | 1998-09-25 | 2001-06-05 | Klaus-Juergen Pees | Fungicidal trihalophenyl-triazolopyrimidines |
| SI0988790T1 (en) | 1998-09-25 | 2003-10-31 | Basf Aktiengesellschaft | Fungicidal mixtures |
| US5985883A (en) | 1998-09-25 | 1999-11-16 | American Cyanamid Company | Fungicidal trichlorophenyl-triazolopyrimidines |
| JP4025468B2 (ja) | 1999-07-29 | 2007-12-19 | 三井化学株式会社 | 有機電界発光素子 |
| WO2001035738A2 (en) | 1999-11-18 | 2001-05-25 | Basf Corporation | Non-aqueous concentrated spreading oil composition |
| US6559151B2 (en) | 2000-05-08 | 2003-05-06 | Basf Aktiengesellschaft | 6-(2-trifluoromethyl-phenyl)-triazolopyrimidines |
| NZ523807A (en) * | 2000-06-30 | 2004-09-24 | Wyeth Corp | Substituted-triazolopyrimidines as anticancer agents |
| AR031396A1 (es) | 2000-08-25 | 2003-09-24 | Basf Ag | Una formulacion fungicida acuosa concentrada para aplicar a las plantas, un metodo de aplicacion de dicha composicion y un kit para la preparacion de una mezcla de aspersion que contiene dicha formulacion |
| ES2226968T3 (es) | 2000-12-06 | 2005-04-01 | Wyeth | 6-(2-trifluorometilfenil)-triazolopirimidinas fungicidas. |
| WO2002067679A1 (en) | 2001-02-19 | 2002-09-06 | Basf Aktiengesellschaft | Fungicidal mixtures |
| NZ528745A (en) | 2001-04-11 | 2005-03-24 | Basf Ag | 5-halogen-6-phenyl-7-fluoralkylamino-triazolopyrimidines as fungicides and their preparation process |
| WO2003022850A1 (en) * | 2001-09-04 | 2003-03-20 | Sumitomo Chemical Company, Limited | IMIDAZO[1,2-a]PYRIMIDINES AND FUNGICIDE COMPOSITIONS CONTAINING THE SAME |
| AU2003211651A1 (en) * | 2002-04-19 | 2003-11-03 | Sumitomo Chemical Company, Limited | 5,6-DIPHENYLIMIDAZO(1,2-a)PYRIMIDINE AND BACTERICIDAL COMPOSITION CONTAINING THE SAME |
-
2004
- 2004-09-17 DE DE602004014525T patent/DE602004014525D1/de not_active Expired - Lifetime
- 2004-09-17 DK DK04784454T patent/DK1684763T3/da active
- 2004-09-17 BR BRPI0414778-2A patent/BRPI0414778A/pt not_active IP Right Cessation
- 2004-09-17 AU AU2004275728A patent/AU2004275728A1/en not_active Withdrawn
- 2004-09-17 EP EP04784454A patent/EP1684763B1/en not_active Expired - Lifetime
- 2004-09-17 CN CNB2004800273126A patent/CN100486580C/zh not_active Expired - Fee Related
- 2004-09-17 AT AT04784454T patent/ATE398452T1/de not_active IP Right Cessation
- 2004-09-17 ES ES04784454T patent/ES2308256T3/es not_active Expired - Lifetime
- 2004-09-17 JP JP2006528080A patent/JP4695595B2/ja not_active Expired - Fee Related
- 2004-09-17 PL PL04784454T patent/PL1684763T3/pl unknown
- 2004-09-17 WO PCT/US2004/030595 patent/WO2005030218A1/en not_active Ceased
- 2004-09-17 MX MXPA06002939A patent/MXPA06002939A/es active IP Right Grant
- 2004-09-17 CA CA002537520A patent/CA2537520A1/en not_active Abandoned
- 2004-09-24 US US10/950,542 patent/US7285555B2/en not_active Expired - Fee Related
-
2007
- 2007-09-19 US US11/903,100 patent/US7915266B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004014525D1 (de) | 2008-07-31 |
| DK1684763T3 (da) | 2008-09-01 |
| JP2007506745A (ja) | 2007-03-22 |
| CN100486580C (zh) | 2009-05-13 |
| AU2004275728A1 (en) | 2005-04-07 |
| CA2537520A1 (en) | 2005-04-07 |
| EP1684763A1 (en) | 2006-08-02 |
| WO2005030218A1 (en) | 2005-04-07 |
| US7915266B2 (en) | 2011-03-29 |
| ES2308256T3 (es) | 2008-12-01 |
| ATE398452T1 (de) | 2008-07-15 |
| US7285555B2 (en) | 2007-10-23 |
| MXPA06002939A (es) | 2006-05-31 |
| JP4695595B2 (ja) | 2011-06-08 |
| CN1856311A (zh) | 2006-11-01 |
| PL1684763T3 (pl) | 2008-11-28 |
| US20050065167A1 (en) | 2005-03-24 |
| US20080255157A1 (en) | 2008-10-16 |
| EP1684763B1 (en) | 2008-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |