BRPI0313424B8 - forma de dosagem e processo para a preparação de uma forma de dosagem - Google Patents

forma de dosagem e processo para a preparação de uma forma de dosagem

Info

Publication number
BRPI0313424B8
BRPI0313424B8 BRPI0313424A BR0313424A BRPI0313424B8 BR PI0313424 B8 BRPI0313424 B8 BR PI0313424B8 BR PI0313424 A BRPI0313424 A BR PI0313424A BR 0313424 A BR0313424 A BR 0313424A BR PI0313424 B8 BRPI0313424 B8 BR PI0313424B8
Authority
BR
Brazil
Prior art keywords
dosage form
active ingredient
preparing
immediate
release
Prior art date
Application number
BRPI0313424A
Other languages
English (en)
Other versions
BR0313424A (pt
BR0313424B1 (pt
Inventor
Vaya Navin
Singh Karan Rajesh
Sadanand Nadkarni Sunil
Kumar Gupta Vinod
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Publication of BR0313424A publication Critical patent/BR0313424A/pt
Publication of BR0313424B1 publication Critical patent/BR0313424B1/pt
Publication of BRPI0313424B8 publication Critical patent/BRPI0313424B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"forma de dosagem e processo para a preparação de uma forma de dosagem". a presente invenção refere-se a uma forma de dosagem compreendendo um ingrediente ativo de alta solubilidade e de alta dose com liberação modificada e um ingrediente ativo de baixa dose com liberação imediata onde a razão de peso do ingrediente ativo de liberação imediata e do ingrediente ativo de liberação modificada é a partir de 1:10 a 1: 15000 e o peso do ingrediente ativo de liberação imediata é a partir de 500 mg a 1500 mg. a presente invenção também refere-se a um processo para a preparação da formulação.
BRPI0313424A 2002-08-05 2003-08-01 forma de dosagem e processo para a preparação de uma forma de dosagem BRPI0313424B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN697MU2002 2002-08-05
IN699MU2002 2002-08-05
IN80MU2003 2003-01-22
IN82MU2003 2003-01-22
PCT/IN2003/000262 WO2004012700A2 (en) 2002-08-05 2003-08-01 Dosage form comprising high dose high soluble active ingredient as modified release and low dose active ingredient as immediate release

Publications (3)

Publication Number Publication Date
BR0313424A BR0313424A (pt) 2005-06-14
BR0313424B1 BR0313424B1 (pt) 2017-10-31
BRPI0313424B8 true BRPI0313424B8 (pt) 2021-05-25

Family

ID=31499436

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0313424A BRPI0313424B8 (pt) 2002-08-05 2003-08-01 forma de dosagem e processo para a preparação de uma forma de dosagem

Country Status (5)

Country Link
US (3) US7985422B2 (pt)
EP (1) EP1528917B1 (pt)
AU (1) AU2003274681A1 (pt)
BR (1) BRPI0313424B8 (pt)
WO (1) WO2004012700A2 (pt)

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US8263125B2 (en) 2012-09-11
US20060024365A1 (en) 2006-02-02
BR0313424A (pt) 2005-06-14
US7985422B2 (en) 2011-07-26
US20060153916A1 (en) 2006-07-13
EP1528917B1 (en) 2013-06-19
WO2004012700A2 (en) 2004-02-12
AU2003274681A8 (en) 2004-02-23
US20040096499A1 (en) 2004-05-20
EP1528917A2 (en) 2005-05-11
AU2003274681A1 (en) 2004-02-23
BR0313424B1 (pt) 2017-10-31

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