BRPI0306143B8 - processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentares - Google Patents
processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentaresInfo
- Publication number
- BRPI0306143B8 BRPI0306143B8 BRPI0306143A BR0306143A BRPI0306143B8 BR PI0306143 B8 BRPI0306143 B8 BR PI0306143B8 BR PI0306143 A BRPI0306143 A BR PI0306143A BR 0306143 A BR0306143 A BR 0306143A BR PI0306143 B8 BRPI0306143 B8 BR PI0306143B8
- Authority
- BR
- Brazil
- Prior art keywords
- granules
- binders
- powders
- production
- coating agents
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title abstract 4
- 239000000843 powder Substances 0.000 title abstract 4
- 239000011230 binding agent Substances 0.000 title abstract 3
- 239000011248 coating agent Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 235000015872 dietary supplement Nutrition 0.000 title abstract 2
- 230000002500 effect on skin Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000005397 methacrylic acid ester group Chemical group 0.000 abstract 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10239999A DE10239999A1 (de) | 2002-08-27 | 2002-08-27 | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
| PCT/EP2003/007319 WO2004019918A1 (de) | 2002-08-27 | 2003-07-08 | Granulat oder pulver zur herstellung von überzugs- und bindemitteln für arzneiformen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0306143A BR0306143A (pt) | 2004-10-19 |
| BRPI0306143B1 BRPI0306143B1 (pt) | 2016-03-08 |
| BRPI0306143B8 true BRPI0306143B8 (pt) | 2021-05-25 |
Family
ID=31197526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0306143A BRPI0306143B8 (pt) | 2002-08-27 | 2003-07-08 | processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentares |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7175857B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1432409B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4571861B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100942667B1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE408401T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003266232A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0306143B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2464502C (cg-RX-API-DMAC7.html) |
| DE (2) | DE10239999A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2314275T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL161145A0 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2004CH00875A (cg-RX-API-DMAC7.html) |
| MX (1) | MX250472B (cg-RX-API-DMAC7.html) |
| PL (1) | PL206233B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI1432409T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004019918A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| DE10260920A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen |
| DE10260921A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
| DE10260919A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug |
| DE10304403A1 (de) * | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| DE102004029573A1 (de) * | 2004-06-18 | 2005-12-29 | Gambro Lundia Ab | MIF-Adsorbent |
| JP4895819B2 (ja) * | 2004-10-29 | 2012-03-14 | 大鵬薬品工業株式会社 | プロピベリン含有経口粉粒状製剤及びその製造法 |
| EP1681049A1 (fr) * | 2005-01-12 | 2006-07-19 | Physica Pharma | Composition pharmaceutique et forme galénique correspondante à délitement rapide en bouche, et procédé de fabrication de cette composition |
| US20060264458A1 (en) * | 2005-05-03 | 2006-11-23 | Jie Du | Quinine dosage forms and methods of use thereof |
| DE102005042039A1 (de) * | 2005-09-02 | 2007-03-08 | Basf Ag | Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität |
| AU2007280471B2 (en) * | 2006-08-04 | 2012-10-18 | Ethypharm | Multilayer orally disintegrating tablet |
| US8790693B2 (en) | 2007-08-02 | 2014-07-29 | Basf Se | Aqueous polymer dispersion based on N,N-diethylaminoethyl methacrylate, its preparation and use |
| WO2010030735A2 (en) * | 2008-09-11 | 2010-03-18 | Aethos Pharmaceuticals, Inc. | Stabilized coating for pharmaceutical formulations |
| JP5693594B2 (ja) | 2009-10-28 | 2015-04-01 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 医薬剤形用の安定な保護コーティング |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| AU2011226324B2 (en) * | 2010-03-10 | 2015-09-24 | Nogra Pharma Limited | Compositions for colon lavage and methods of making and using same |
| EP2568964B1 (en) * | 2010-05-10 | 2018-08-01 | Evonik Röhm GmbH | Pharmaceutical dosage form comprising one or more antiretroviral active ingredients |
| WO2012031934A1 (de) | 2010-09-07 | 2012-03-15 | Basf Se | Verwendung von copolymeren auf basis von aminogruppenhaltigen polymeren als matrixbindemittel für die herstellung von wirkstoffhaltigen granulaten und darreichungsformen |
| US9795576B2 (en) | 2010-09-27 | 2017-10-24 | Basf Se | Protective coatings for acidic active ingredients |
| EP2621479B1 (de) | 2010-09-27 | 2017-11-29 | Basf Se | Protektive überzüge für saure wirkstoffe |
| WO2012116940A1 (de) | 2011-02-28 | 2012-09-07 | Basf Se | Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen |
| BR112013021510B1 (pt) | 2011-02-28 | 2020-09-24 | Basf Se | Processo para a produção de composições de revestimento em pó, e, uso de um pó de polímero |
| US8865250B2 (en) | 2011-02-28 | 2014-10-21 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US8962064B2 (en) | 2011-02-28 | 2015-02-24 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US9044734B2 (en) | 2011-09-23 | 2015-06-02 | Basf Se | Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion |
| US20130236505A1 (en) | 2012-03-09 | 2013-09-12 | Basf Se | Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment |
| EP2636403A1 (de) * | 2012-03-09 | 2013-09-11 | Basf Se | Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu |
| WO2013189776A1 (de) | 2012-06-22 | 2013-12-27 | Basf Se | Wirkstoffhaltige festen dispersionen auf basis von diethylaminoethylmethacrylat-copolymeren |
| US10668156B2 (en) | 2012-06-22 | 2020-06-02 | Basf Se | Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers |
| US20150290136A1 (en) * | 2012-11-22 | 2015-10-15 | Evonik Roehm Gmbh | Process for preparing a granulated product from a powder composition |
| FR3027802B1 (fr) * | 2014-10-31 | 2018-03-02 | Ethypharm | Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant |
| GR1008992B (el) * | 2015-12-17 | 2017-03-23 | Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων | Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης |
| EP3569225A1 (en) * | 2018-05-18 | 2019-11-20 | Pharmaceutical Oriented Services Ltd | Solid dispersion containing ritonavir |
| JP7058763B2 (ja) * | 2018-12-27 | 2022-04-22 | 興和株式会社 | 医薬品 |
| AU2021391823A1 (en) | 2020-12-03 | 2023-06-29 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| IL307454A (en) | 2021-04-07 | 2023-12-01 | Battelle Memorial Institute | Technologies for rapid design, construction, testing, learning to identify and use non-viral vectors |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3581428D1 (de) | 1984-06-13 | 1991-02-28 | Roehm Gmbh | Verfahren zum ueberziehen von arzneiformen. |
| DE3920082A1 (de) | 1989-06-20 | 1991-03-07 | Roehm Gmbh | Filmbildendes waessriges ueberzugsmittel fuer feste arzneimittel, verfahren zu seiner herstellung und verwendung |
| DE29502547U1 (de) | 1995-02-16 | 1995-03-30 | Röhm GmbH, 64293 Darmstadt | Thermoplastisches Überzugs- und Bindemittel für Arzneiformen |
| DE19918435A1 (de) * | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Überzugs- und Bindemittel für orale oder dermale Arzneiformen |
| DE19958007A1 (de) * | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| BR0017261A (pt) * | 2000-07-14 | 2003-07-29 | Immunivest Corp | Métodos para isolamento de uma bioentidade alvo de uma amostra biológica e de células de tumor com densidade de antìgeno baixa e, kits para inibir a agregação endógena de partìculas magnéticas coloidais no processamento de material biológico e, para isolamento de células de tumor de densidade de antìgeno baixa de uma amostra biológica com agregação ontrolada de partìculas magnéticas coloidais |
| SK288049B6 (sk) * | 2001-02-27 | 2013-03-01 | Evonik Rohm Gmbh | Coating and binding agent, its use for production of cover oral or dermal pharmaceutical dosage forms, process for its production and dosage form containing same |
| DE10208344A1 (de) * | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
-
2002
- 2002-08-27 DE DE10239999A patent/DE10239999A1/de not_active Withdrawn
-
2003
- 2003-07-08 DE DE50310506T patent/DE50310506D1/de not_active Expired - Lifetime
- 2003-07-08 SI SI200331454T patent/SI1432409T1/sl unknown
- 2003-07-08 AT AT03790791T patent/ATE408401T1/de active
- 2003-07-08 ES ES03790791T patent/ES2314275T3/es not_active Expired - Lifetime
- 2003-07-08 AU AU2003266232A patent/AU2003266232A1/en not_active Abandoned
- 2003-07-08 IL IL16114503A patent/IL161145A0/xx unknown
- 2003-07-08 JP JP2004531794A patent/JP4571861B2/ja not_active Expired - Lifetime
- 2003-07-08 CA CA2464502A patent/CA2464502C/en not_active Expired - Lifetime
- 2003-07-08 EP EP03790791A patent/EP1432409B1/de not_active Expired - Lifetime
- 2003-07-08 BR BRPI0306143A patent/BRPI0306143B8/pt active IP Right Grant
- 2003-07-08 MX MXPA04003970 patent/MX250472B/es active IP Right Grant
- 2003-07-08 US US10/489,856 patent/US7175857B2/en not_active Expired - Lifetime
- 2003-07-08 PL PL368186A patent/PL206233B1/pl unknown
- 2003-07-08 WO PCT/EP2003/007319 patent/WO2004019918A1/de not_active Ceased
-
2004
- 2004-03-29 IL IL161145A patent/IL161145A/en active IP Right Grant
- 2004-04-26 IN IN875CH2004 patent/IN2004CH00875A/en unknown
- 2004-04-27 KR KR20047006270A patent/KR100942667B1/ko not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040249035A1 (en) | 2004-12-09 |
| ES2314275T3 (es) | 2009-03-16 |
| AU2003266232A1 (en) | 2004-03-19 |
| CA2464502A1 (en) | 2004-03-11 |
| JP2005536555A (ja) | 2005-12-02 |
| DE10239999A1 (de) | 2004-03-04 |
| PL368186A1 (en) | 2005-03-21 |
| BRPI0306143B1 (pt) | 2016-03-08 |
| MX250472B (es) | 2007-10-17 |
| US7175857B2 (en) | 2007-02-13 |
| BR0306143A (pt) | 2004-10-19 |
| EP1432409A1 (de) | 2004-06-30 |
| ATE408401T1 (de) | 2008-10-15 |
| DE50310506D1 (de) | 2008-10-30 |
| SI1432409T1 (sl) | 2009-02-28 |
| IL161145A0 (en) | 2004-08-31 |
| MXPA04003970A (es) | 2004-06-22 |
| US20050197434A9 (en) | 2005-09-08 |
| KR20050034620A (ko) | 2005-04-14 |
| WO2004019918A1 (de) | 2004-03-11 |
| IL161145A (en) | 2010-11-30 |
| CA2464502C (en) | 2010-11-23 |
| JP4571861B2 (ja) | 2010-10-27 |
| IN2004CH00875A (cg-RX-API-DMAC7.html) | 2006-01-13 |
| PL206233B1 (pl) | 2010-07-30 |
| EP1432409B1 (de) | 2008-09-17 |
| KR100942667B1 (ko) | 2010-02-17 |
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