BRPI0013439A - composição compreendendo tramadol e um fármaco anticonvulsivante. - Google Patents

composição compreendendo tramadol e um fármaco anticonvulsivante.

Info

Publication number
BRPI0013439A
BRPI0013439A BRPI0013439A BRPI0013439A BRPI0013439A BR PI0013439 A BRPI0013439 A BR PI0013439A BR PI0013439 A BRPI0013439 A BR PI0013439A BR PI0013439 A BRPI0013439 A BR PI0013439A BR PI0013439 A BRPI0013439 A BR PI0013439A
Authority
BR
Brazil
Prior art keywords
composition
anticonvulsant drug
tramadol
tramadol material
anticonvulsant
Prior art date
Application number
BRPI0013439A
Other languages
English (en)
Inventor
Ellen E Codd
Rebecca P Martinez
Kathryn E Rogers
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of BRPI0013439A publication Critical patent/BRPI0013439A/pt
Publication of BRPI0013439B1 publication Critical patent/BRPI0013439B1/pt
Publication of BRPI0013439B8 publication Critical patent/BRPI0013439B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

patente de invenção: "composição compreendendo um material de tramadol e uma droga anticonvulsiva". a presente invenção refere-se a uma composição farmacêutica compreendendo uma combinação de um material de tramadol e uma droga anticonvulsiva e ao uso farmacológico da composição no tratamento de dor e distúrbios neurológicos ou psiquiátricos. a composição produz um produto combinado tendo propriedades aperfeiçoadas, requerendo menos de cada ingrediente e produzindo um efeito sinergístico.
BRPI0013439-2 1999-08-20 2000-08-09 composiÇço compreendendo tramadol e um fÁrmaco anticonvulsivante. BRPI0013439B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15020199P 1999-08-20 1999-08-20
PCT/US2000/021622 WO2001013904A2 (en) 1999-08-20 2000-08-09 Composition comprising a tramadol material and an anticonvulsant drug

Publications (3)

Publication Number Publication Date
BRPI0013439A true BRPI0013439A (pt) 2002-04-30
BRPI0013439B1 BRPI0013439B1 (pt) 2012-07-24
BRPI0013439B8 BRPI0013439B8 (pt) 2021-07-06

Family

ID=22533492

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0013439-2 BRPI0013439B8 (pt) 1999-08-20 2000-08-09 composiÇço compreendendo tramadol e um fÁrmaco anticonvulsivante.

Country Status (31)

Country Link
US (1) US6562865B1 (pt)
EP (1) EP1210118B1 (pt)
JP (1) JP4977297B2 (pt)
KR (1) KR100758609B1 (pt)
CN (1) CN1198651C (pt)
AR (1) AR032132A1 (pt)
AT (1) ATE284223T1 (pt)
AU (1) AU782759B2 (pt)
BG (1) BG65996B1 (pt)
BR (1) BRPI0013439B8 (pt)
CA (1) CA2381797C (pt)
CO (1) CO5190667A1 (pt)
CR (1) CR6593A (pt)
CZ (1) CZ2002524A3 (pt)
DE (1) DE60016602T2 (pt)
EA (1) EA006598B1 (pt)
ES (1) ES2234651T3 (pt)
HU (1) HUP0203198A3 (pt)
IL (2) IL148019A0 (pt)
MX (1) MXPA02001820A (pt)
MY (1) MY136985A (pt)
NO (1) NO332342B1 (pt)
NZ (1) NZ517106A (pt)
PL (1) PL213323B1 (pt)
PT (1) PT1210118E (pt)
SK (1) SK286621B6 (pt)
TR (1) TR200201067T2 (pt)
TW (1) TWI259769B (pt)
UA (1) UA75868C2 (pt)
WO (1) WO2001013904A2 (pt)
ZA (1) ZA200201403B (pt)

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IL148019A (en) 2012-03-29
ZA200201403B (en) 2003-07-30
NO20020728L (no) 2002-04-05
IL148019A0 (en) 2002-09-12
MXPA02001820A (es) 2003-07-14
BG106420A (bg) 2002-09-30
CO5190667A1 (es) 2002-08-29
CR6593A (es) 2009-01-16
JP2003507421A (ja) 2003-02-25
UA75868C2 (en) 2006-06-15
NO20020728D0 (no) 2002-02-13
DE60016602T2 (de) 2005-11-03
SK286621B6 (sk) 2009-02-05
HUP0203198A2 (hu) 2003-02-28
KR100758609B1 (ko) 2007-09-13
EA006598B1 (ru) 2006-02-24
BRPI0013439B8 (pt) 2021-07-06
CN1198651C (zh) 2005-04-27
EP1210118B1 (en) 2004-12-08
HUP0203198A3 (en) 2005-07-28
BG65996B1 (bg) 2010-09-30
TR200201067T2 (tr) 2002-09-23
JP4977297B2 (ja) 2012-07-18
ATE284223T1 (de) 2004-12-15
CN1379686A (zh) 2002-11-13
PL353266A1 (en) 2003-11-03
AU6895800A (en) 2001-03-19
AU782759B2 (en) 2005-08-25
MY136985A (en) 2008-12-31
NO332342B1 (no) 2012-09-03
TWI259769B (en) 2006-08-11
EA200200183A1 (ru) 2002-08-29
BRPI0013439B1 (pt) 2012-07-24
PT1210118E (pt) 2005-02-28
CZ2002524A3 (cs) 2002-11-13
WO2001013904A3 (en) 2001-06-14
WO2001013904A2 (en) 2001-03-01
PL213323B1 (pl) 2013-02-28
ES2234651T3 (es) 2005-07-01
NZ517106A (en) 2005-04-29
KR20020025221A (ko) 2002-04-03
EP1210118A2 (en) 2002-06-05
SK2262002A3 (en) 2003-02-04
CA2381797A1 (en) 2001-03-01
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CA2381797C (en) 2008-04-15
DE60016602D1 (de) 2005-01-13

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