BR9916848A - Processo para produzir intermediários de ácido ascórbico - Google Patents

Processo para produzir intermediários de ácido ascórbico

Info

Publication number
BR9916848A
BR9916848A BR9916848-0A BR9916848A BR9916848A BR 9916848 A BR9916848 A BR 9916848A BR 9916848 A BR9916848 A BR 9916848A BR 9916848 A BR9916848 A BR 9916848A
Authority
BR
Brazil
Prior art keywords
ascorbic acid
acid intermediates
producing ascorbic
methods
producing
Prior art date
Application number
BR9916848-0A
Other languages
English (en)
Inventor
Matthew G Boston
Barbara A Swanson
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Publication of BR9916848A publication Critical patent/BR9916848A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Furan Compounds (AREA)

Abstract

"PROCESSO PARA PRODUZIR INTERMEDIáRIOS DE áCIDO ASCóRBICO". A presente invenção refere-se a processos não-fermentativos para a produção de intermediários de ASA, KDG, DKG e KLG e processos para a regeneração de co-fator. A invenção provê células hospedeiras geneticamente engenheiradas compreendendo ácido nucléico heterólogo codificando enzimas utilizáveis no processo.
BR9916848-0A 1998-12-22 1999-12-22 Processo para produzir intermediários de ácido ascórbico BR9916848A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/218,700 US6599722B2 (en) 1998-12-22 1998-12-22 Method for producing ascorbic acid intermediates
PCT/US1999/030918 WO2000037667A1 (en) 1998-12-22 1999-12-22 Method for producing ascorbic acid intermediates

Publications (1)

Publication Number Publication Date
BR9916848A true BR9916848A (pt) 2002-11-05

Family

ID=22816130

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9916848-0A BR9916848A (pt) 1998-12-22 1999-12-22 Processo para produzir intermediários de ácido ascórbico

Country Status (15)

Country Link
US (4) US6599722B2 (pt)
EP (1) EP1141368B1 (pt)
JP (1) JP2003517278A (pt)
KR (1) KR100750363B1 (pt)
CN (1) CN1247790C (pt)
AT (1) ATE326542T1 (pt)
AU (1) AU2485500A (pt)
BR (1) BR9916848A (pt)
CA (2) CA2371534C (pt)
CZ (1) CZ298605B6 (pt)
DE (1) DE69931394T2 (pt)
DK (1) DK1141368T3 (pt)
MX (1) MXPA01006337A (pt)
PL (1) PL351711A1 (pt)
WO (1) WO2000037667A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024314A1 (de) * 2000-05-17 2001-11-22 Basf Ag Verfahren, umfassend die indirekte elektrochemische Regeneration von NAD(P)H
ATE513036T1 (de) 2001-04-04 2011-07-15 Danisco Us Inc Entkoppelte anabole und katabole stoffwechselwege in wirtszellen
JP2005510999A (ja) * 2001-04-04 2005-04-28 ジェネンコー・インターナショナル・インク 宿主細胞における生成物の生産方法
ATE443996T1 (de) 2002-02-22 2009-10-15 Genencor Int Bräunungsmittel
FI20020592A (fi) * 2002-03-27 2003-09-28 Danisco Sweeteners Oy Menetelmä sokereiden, sokerialkoholien, hiilihydraattien ja niiden seosten erottamiseksi niitä sisältävistä liuoksista
CA2865180A1 (en) 2002-08-16 2004-02-26 Genencor International, Inc. Novel variant hyprocrea jecorina cbh1 cellulases
CA2526595C (en) * 2003-05-22 2014-10-07 Genencor International, Inc. Metabolically engineered bacterial strains having non-functional endogenous gluconate transporters
JPWO2005001066A1 (ja) * 2003-06-18 2006-11-02 住友ベークライト株式会社 新規分解菌及びそれを用いた有機化合物の分解処理方法
CA2533936C (en) * 2003-07-30 2013-09-10 Genencor International, Inc. Metabolically engineered bacterial strains having enhanced 2-keto-d-gluconate accumulation
DK2292747T3 (en) * 2004-12-30 2017-04-24 Danisco Us Inc CBH2 CELLULASE VARIETIES OF HYPOCREA JECORINA
WO2006084664A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene rcs 09
EP1854893A4 (en) * 2005-02-25 2008-06-18 Kaneka Corp PROCESS FOR PRODUCING OPTICALLY ACTIVE SECONDARY ALCOHOL
WO2007028611A2 (en) * 2005-09-09 2007-03-15 Dsm Ip Assets B.V. Process for biomass production using a microorganism with a disrupted glucose-dehydrogenase gene (gms 01)
ES2379969T3 (es) 2007-07-06 2012-05-07 Basf Se Proceso para la producción de una solución de glucosa acuosa a partir de maíz
AU2009256171B2 (en) 2008-06-06 2013-11-07 Danisco Us Inc. Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
EP2626421B1 (en) 2008-12-10 2014-03-19 Direvo Industrial Biotechnology GmbH Improved enzymes for biomass conversion
WO2010141779A1 (en) 2009-06-03 2010-12-09 Danisco Us Inc. Cellulase variants with improved expression, activity and/or stability, and use thereof
EP2931887A1 (en) 2012-12-12 2015-10-21 Danisco US Inc. Variants of cellobiohydrolases
EP3192866A1 (en) 2016-01-15 2017-07-19 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Endocellulases and uses thereof
EP3502126A1 (en) 2017-12-19 2019-06-26 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Ancestral cellulases and uses thereof
US11708571B2 (en) 2018-05-17 2023-07-25 Bp Corporation North America Inc. Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
CN109055292B (zh) * 2018-08-20 2020-08-04 上海凌凯医药科技有限公司 一种生产l-木糖的重组变形假单胞菌及其应用
CN112430560B (zh) * 2019-08-26 2024-01-05 中国科学院分子植物科学卓越创新中心 一种2-酮基-l-古龙酸生产菌株及其构建方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3790444A (en) 1971-03-09 1974-02-05 Daiichi Seiyaku Co Process for preparing diketogluconic acid
JPS6041596B2 (ja) 1980-08-14 1985-09-18 塩野義製薬株式会社 ２，５−ジケト−ｄ−グルコン酸の製造方法
JPS58162298A (ja) 1982-03-05 1983-09-26 Shionogi & Co Ltd ２−ケト−ｌ−グロン酸の製造方法
US5004690A (en) 1983-06-28 1991-04-02 Genetech, Inc. Ascorbic acid intermediates and process enzymes
US4757012A (en) 1983-06-28 1988-07-12 Genentech, Inc. Ascorbic acid intermediates and process enzymes
US4758514A (en) * 1983-06-28 1988-07-19 Genentech, Inc. Ascorbic acid intermediates and process enzymes
DE3326546A1 (de) 1983-07-22 1985-02-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Verfahren zur kontinuierlichen enzymatischen herstellung von gluconsaeure oder ihren derivaten und sorbit und/oder mannit
US5008193A (en) 1984-06-14 1991-04-16 Genentech, Inc. Ascorbic acid intermediates and process enzymes
GB8519536D0 (en) 1985-08-02 1985-09-11 Biogen Nv Vitamin c precursor
US5032514A (en) 1988-08-08 1991-07-16 Genentech, Inc. Metabolic pathway engineering to increase production of ascorbic acid intermediates
GB8826429D0 (en) 1988-11-11 1988-12-14 Univ Leeds Ind Service Ltd Enzyme stabilisation systems
US5376544A (en) 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
US5795761A (en) * 1996-01-11 1998-08-18 Rutgers, The State University Of New Jersey Mutants of 2,5-diketo-D-gluconic acid (2,5-DKG) reductase A

Also Published As

Publication number Publication date
CA2776920A1 (en) 2000-06-29
CZ20012285A3 (cs) 2001-10-17
CZ298605B6 (cs) 2007-11-21
CA2371534C (en) 2012-07-17
WO2000037667A1 (en) 2000-06-29
DE69931394D1 (de) 2006-06-22
AU2485500A (en) 2000-07-12
KR20010093149A (ko) 2001-10-27
US20020177197A1 (en) 2002-11-28
US20020177198A1 (en) 2002-11-28
US6599722B2 (en) 2003-07-29
EP1141368A1 (en) 2001-10-10
EP1141368B1 (en) 2006-05-17
CN1331749A (zh) 2002-01-16
JP2003517278A (ja) 2003-05-27
US20040180413A1 (en) 2004-09-16
MXPA01006337A (es) 2002-04-24
CA2371534A1 (en) 2000-06-29
DK1141368T3 (da) 2006-09-18
KR100750363B1 (ko) 2007-08-17
US20050227337A1 (en) 2005-10-13
CN1247790C (zh) 2006-03-29
PL351711A1 (en) 2003-06-02
DE69931394T2 (de) 2007-05-03
ATE326542T1 (de) 2006-06-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5O, 6O E 7O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.