BR9900776A - Preparo de um preparado de carotenóide pulverizável finamente dividido. - Google Patents

Preparo de um preparado de carotenóide pulverizável finamente dividido.

Info

Publication number
BR9900776A
BR9900776A BR9900776-2A BR9900776A BR9900776A BR 9900776 A BR9900776 A BR 9900776A BR 9900776 A BR9900776 A BR 9900776A BR 9900776 A BR9900776 A BR 9900776A
Authority
BR
Brazil
Prior art keywords
preparation
sprayable
carotenoid
suspension
finely divided
Prior art date
Application number
BR9900776-2A
Other languages
English (en)
Other versions
BR9900776A8 (pt
BR9900776B1 (pt
Inventor
Hermann Stein
Klaus Viardot
Bin Yang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR9900776A publication Critical patent/BR9900776A/pt
Publication of BR9900776B1 publication Critical patent/BR9900776B1/pt
Publication of BR9900776A8 publication Critical patent/BR9900776A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"PREPARO DE UM PREPARADO DE CAROTENóIDE PULVERIZáVEL FINAMENTE DIVIDIDO''<D>. A presente invenção refere-se a um processo contínuo para o preparo de um preparado corante natural, carotenóide ou retinóide pulverizável, em que o ingrediente ativo é finamente dividido, esse processo compreende as etapas de: a) formação de uma suspensão do ingrediente ativo em um solvente orgânico não miscível em água contendo opcionalmente um antioxidante e/ou um óleo, b) alimentação da suspensão da etapa a) a um permutador de calor e aquecimento da referida suspensão para 100-250°C, por meio do qual o tempo de residência no permutador de calor é menos do que 5 segundos, c) mistura rápida da solução da etapa b) em uma temperatura na faixa de 20-100°C com uma solução aquosa de um colóide intumescível contendo opcionalmente um estabilizador, d) remoção do solvente orgânico, e e) conversão da dispersão da etapa d) em um preparado pulverizável.
BRPI9900776A 1998-02-23 1999-02-22 preparo de um preparado de carotenóide pulverizável finamente dividido BR9900776A8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98103113 1998-02-23

Publications (3)

Publication Number Publication Date
BR9900776A true BR9900776A (pt) 2000-03-28
BR9900776B1 BR9900776B1 (pt) 2011-05-31
BR9900776A8 BR9900776A8 (pt) 2018-03-20

Family

ID=8231467

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9900776A BR9900776A8 (pt) 1998-02-23 1999-02-22 preparo de um preparado de carotenóide pulverizável finamente dividido

Country Status (16)

Country Link
US (1) US6406735B2 (pt)
EP (1) EP0937412B1 (pt)
JP (1) JP4837812B2 (pt)
KR (1) KR100695589B1 (pt)
CN (1) CN1173637C (pt)
AU (1) AU743535B2 (pt)
BR (1) BR9900776A8 (pt)
CA (1) CA2261456A1 (pt)
DE (1) DE69929641T2 (pt)
ES (1) ES2257828T3 (pt)
ID (1) ID23623A (pt)
IN (1) IN1999CH00212A (pt)
MX (1) MX224632B (pt)
NO (1) NO315892B1 (pt)
PH (1) PH11999000351B1 (pt)
TW (1) TW565434B (pt)

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ES2279695B1 (es) * 2005-08-01 2008-08-01 Jesus Antas Pharma, S.A. Nuevas formulaciones solidas de carotenoides y procedimiento para su obtencion.
CA2618447C (en) * 2005-08-15 2015-06-02 Phares Pharmaceutical Research N.V. Crystal forms of astaxanthin
EP1886584A1 (en) * 2006-08-08 2008-02-13 Indena S.P.A. Stable and bioavailable compositions of isomers of lycopene for skin and hair
US7435846B2 (en) 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
ATE501644T1 (de) 2007-01-16 2011-04-15 Basf Se Flüssige formulierungen enthaltend carotinoide
EP1967081A1 (en) 2007-03-05 2008-09-10 DSMIP Assets B.V. Process for the manufacture of a powder containing carotenoids
WO2008137831A1 (en) * 2007-05-07 2008-11-13 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Water-soluble nanoparticles containing water-insoluble compounds
WO2009040818A1 (en) 2007-09-25 2009-04-02 Solubest Ltd Compositions comprising lipophilic active compounds and method for their preparation
CN101396068B (zh) * 2007-09-27 2013-05-01 浙江医药股份有限公司新昌制药厂 类胡萝卜素制剂及其应用和包含该制剂的饲料及其制备方法
CN105077203A (zh) 2007-11-29 2015-11-25 巴斯夫欧洲公司 用于饮料着色的粉状类胡萝卜素制剂
JP2011505157A (ja) * 2007-12-05 2011-02-24 ディーエスエム アイピー アセッツ ビー．ブイ． 脂溶性活性成分の微粉砕状調合物
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CN101297691B (zh) * 2008-06-06 2011-12-14 成都建福化学品有限公司 稳定的水溶性类胡萝卜素干粉的制备方法
EP2343986B2 (de) 2008-10-07 2021-04-21 Basf Se Gebrauchfertige, stabile emulsion
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Also Published As

Publication number Publication date
JP2000186224A (ja) 2000-07-04
DE69929641T2 (de) 2006-12-14
TW565434B (en) 2003-12-11
ID23623A (id) 2000-05-04
US6406735B2 (en) 2002-06-18
ES2257828T3 (es) 2006-08-01
IN1999CH00212A (pt) 2007-05-18
EP0937412B1 (en) 2006-02-01
PH11999000351B1 (en) 2004-02-11
MX224632B (es) 2004-12-03
BR9900776A8 (pt) 2018-03-20
US20010008644A1 (en) 2001-07-19
NO990852L (no) 1999-08-24
EP0937412A1 (en) 1999-08-25
AU743535B2 (en) 2002-01-31
AU1836299A (en) 1999-09-09
BR9900776B1 (pt) 2011-05-31
CN1231843A (zh) 1999-10-20
KR19990072792A (ko) 1999-09-27
NO990852D0 (no) 1999-02-23
DE69929641D1 (de) 2006-04-13
MX9901754A (es) 2000-02-28
CA2261456A1 (en) 1999-08-23
JP4837812B2 (ja) 2011-12-14
CN1173637C (zh) 2004-11-03
KR100695589B1 (ko) 2007-03-14
NO315892B1 (no) 2003-11-10

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B25A Requested transfer of rights approved

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B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 31/05/2011, OBSERVADAS AS CONDICOES LEGAIS.

B03H Publication of an application: rectification [chapter 3.8 patent gazette]

Free format text: REFERENTE A RPI 1525 DE 28/03/2000, QUANTO AO ITEM (54).

B15K Others concerning applications: alteration of classification

Ipc: C07C 403/24 (2006.01), A23L 5/44 (2016.0

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 20A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2502 DE 18-12-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.