BR9814772A - Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose - Google Patents

Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose

Info

Publication number
BR9814772A
BR9814772A BR9814772-2A BR9814772A BR9814772A BR 9814772 A BR9814772 A BR 9814772A BR 9814772 A BR9814772 A BR 9814772A BR 9814772 A BR9814772 A BR 9814772A
Authority
BR
Brazil
Prior art keywords
treatment
oral administration
leishmaniasis
solid pharmaceutical
compositions containing
Prior art date
Application number
BR9814772-2A
Other languages
English (en)
Inventor
Juercen Engel
Werner Likiotis
Thomas Klenner
Peter Hilgard
Dieter Sauerbier
Eckhard Millmann
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Priority to BR9814772-2A priority Critical patent/BR9814772A/pt
Publication of BR9814772A publication Critical patent/BR9814772A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES FARMACêUTICAS SóLIDAS QUE CONTêM MILTEFOSINA PARA ADMINISTRAçãO ORAL NO TRATAMENTO DE LEISHMANIOSE"<D>. A presente invenção refere-se a novas composições farmacêuticas sólidas que contêm hexadecilfosfocolina (miltefosina) para administração oral no tratamento de leishmaniose, a um processo para a produção da dita composição farmacêutica, a um esquema de dosagem para administração oral da composição farmacêutica no tratamento de leishmaniose, e, finalmente, a uma combinação que compreende a composição farmacêutica sólida, um antiemético e/ou um antidiarréico.
BR9814772-2A 1998-01-22 1998-01-22 Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose BR9814772A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR9814772-2A BR9814772A (pt) 1998-01-22 1998-01-22 Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1998/000345 WO1999037289A1 (en) 1998-01-22 1998-01-22 Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis
BR9814772-2A BR9814772A (pt) 1998-01-22 1998-01-22 Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose

Publications (1)

Publication Number Publication Date
BR9814772A true BR9814772A (pt) 2000-10-24

Family

ID=8166843

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814772-2A BR9814772A (pt) 1998-01-22 1998-01-22 Composições farmacêuticas sólidas que contêm miltefosina para administração oral no tratamento de leishmaniose

Country Status (24)

Country Link
US (1) US6544551B1 (pt)
EP (1) EP1051159B1 (pt)
JP (1) JP2002501015A (pt)
KR (1) KR100517399B1 (pt)
CN (1) CN100413492C (pt)
AT (1) ATE215817T1 (pt)
AU (1) AU756805B2 (pt)
BR (1) BR9814772A (pt)
CA (1) CA2318260C (pt)
CZ (1) CZ299229B6 (pt)
DE (1) DE69804865T2 (pt)
DK (1) DK1051159T3 (pt)
ES (1) ES2175663T3 (pt)
HU (1) HUP0004363A3 (pt)
IL (1) IL136196A (pt)
NO (1) NO20003674L (pt)
NZ (1) NZ505648A (pt)
PL (1) PL189654B1 (pt)
PT (1) PT1051159E (pt)
SI (1) SI1051159T1 (pt)
SK (1) SK284839B6 (pt)
TR (1) TR200001717T2 (pt)
UA (1) UA68372C2 (pt)
WO (1) WO1999037289A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10203195A1 (de) * 2002-01-25 2003-08-07 Zentaris Ag Verwendung von Alkylphosphocholinen in der Präventivbehandlung von Protozoenerkrankungen
US7887817B2 (en) * 2002-01-25 2011-02-15 Aeterna Zentaris Gmbh Process for preventing protozoal diseases
BR0215680A (pt) * 2002-04-26 2005-02-01 Rudolf Perl Composição farmacêutica oral estável
US8383605B2 (en) 2002-07-30 2013-02-26 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
PL375493A1 (en) * 2002-07-30 2005-11-28 Zentaris Gmbh Use of alkyl phosphocholines in combination with antitumor medicaments
AU2004269903B2 (en) 2003-09-09 2010-09-02 Biogen International Gmbh The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
PL2801354T3 (pl) 2004-10-08 2017-08-31 Forward Pharma A/S Kompozycje farmaceutyczne o kontrolowanym uwalnianiu zawierające ester kwasu fumarowego
US8703179B2 (en) * 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
WO2010020276A1 (en) * 2008-08-19 2010-02-25 Orphanidis Pharma Research Gmbh Treatment of coccidian parasites
WO2011123691A1 (en) 2010-03-31 2011-10-06 Keryx Biopharmaceuticals, Inc. Perifosine and capecitabine as a combined treatment for cancer
CA2818194A1 (en) 2010-11-22 2012-05-31 Dafra Pharma Research&Development Bvba Solid dosage forms of oleyl phosphocholine
JP6441073B2 (ja) 2011-06-24 2018-12-19 ジーアールアイ バイオ, インコーポレイテッドGRI Bio, Inc. 炎症状態の予防および処置
JP2016515602A (ja) * 2013-04-08 2016-05-30 アカデミッシュ メディッシュ セントラム Ｉｂｄの治療に使用するためのミルテホシンまたはペリホシン
JP6566450B2 (ja) 2014-09-17 2019-08-28 ステアライフ・インディア・プライベート・リミテッド 発泡組成物及びそれを製造する方法
CN104473941A (zh) * 2014-12-20 2015-04-01 长沙佰顺生物科技有限公司 一种含有米替福新的药物制剂及其制备方法
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
BR112021020389A2 (pt) * 2019-04-12 2021-12-07 Oblita Therapeutics Bvba Formulações de dosagem em comprimidos de oleil fosfocolina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE888444C (de) * 1951-11-10 1953-08-31 Benckiser Gmbh Joh A Verfahren zum Tablettieren von hygroskopischen Praeparaten
IE59777B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicaments
US4762658A (en) * 1986-10-08 1988-08-09 Central Soya Company, Inc. Method of tableting of de-oiled phosphatides (lecithin)
EP0916343A1 (de) * 1989-09-27 1999-05-19 ASTA Medica Aktiengesellschaft Verwendung von Alkylphosphorsäure-Verbindungen zur Bekämpfung von Psoriasis-Erkrankungen
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis

Also Published As

Publication number Publication date
WO1999037289A1 (en) 1999-07-29
AU6212198A (en) 1999-08-09
DE69804865T2 (de) 2002-11-07
JP2002501015A (ja) 2002-01-15
AU756805B2 (en) 2003-01-23
KR20010034311A (ko) 2001-04-25
CN100413492C (zh) 2008-08-27
EP1051159B1 (en) 2002-04-10
IL136196A (en) 2004-07-25
SK9862000A3 (en) 2000-11-07
NO20003674D0 (no) 2000-07-18
NZ505648A (en) 2002-10-25
US6544551B1 (en) 2003-04-08
PL189654B1 (pl) 2005-09-30
ATE215817T1 (de) 2002-04-15
NO20003674L (no) 2000-07-18
PT1051159E (pt) 2002-09-30
CA2318260A1 (en) 1999-07-29
ES2175663T3 (es) 2002-11-16
TR200001717T2 (tr) 2000-11-21
CZ20002596A3 (cs) 2000-10-11
PL342838A1 (en) 2001-07-16
DE69804865D1 (de) 2002-05-16
CN1283111A (zh) 2001-02-07
SI1051159T1 (en) 2002-10-31
IL136196A0 (en) 2001-05-20
HUP0004363A3 (en) 2002-12-28
SK284839B6 (sk) 2005-12-01
UA68372C2 (en) 2004-08-16
CA2318260C (en) 2006-11-21
KR100517399B1 (ko) 2005-09-28
CZ299229B6 (cs) 2008-05-21
DK1051159T3 (da) 2002-08-05
EP1051159A1 (en) 2000-11-15
HUP0004363A2 (hu) 2001-04-28

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: ZENTARIS AG (DE)

B25A Requested transfer of rights approved

Owner name: BLITZ F02-570 GMBH (DE)

Free format text: TRANSFERIDO DE: ZENTARIS AG

B25D Requested change of name of applicant approved

Owner name: ZENTARIS GMBH (DE)

Free format text: ALTERADO DE: BLITZ F02-570 GMBH

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISITO DE NOVIDADE ( ART. 8O COMBINADO COM 11 DA LPI )

B12B Appeal against refusal [chapter 12.2 patent gazette]