BR9810072A - Formulação farmacêutica semi-sólida contendo dexcetoprofen trometamol - Google Patents

Formulação farmacêutica semi-sólida contendo dexcetoprofen trometamol

Info

Publication number
BR9810072A
BR9810072A BR9810072-6A BR9810072A BR9810072A BR 9810072 A BR9810072 A BR 9810072A BR 9810072 A BR9810072 A BR 9810072A BR 9810072 A BR9810072 A BR 9810072A
Authority
BR
Brazil
Prior art keywords
dexcetoprofen
trometamol
semi
pharmaceutical formulation
solid pharmaceutical
Prior art date
Application number
BR9810072-6A
Other languages
English (en)
Other versions
BR9810072B1 (pt
Inventor
David Mauleon Casellas
Albert Palomer Benet
Luisa Garcia Perez
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of BR9810072A publication Critical patent/BR9810072A/pt
Publication of BR9810072B1 publication Critical patent/BR9810072B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"FORMULAçãO FARMACêUTICA SEMI-SóLIDA CONTENDO DEXCETOPROFEN TROMETAMOL''<D>. A presente invenção refere-se a um processo para o preparo de uma formulação farmacêutica semi-sólida (gel ou creme) contendo dexcetoprofen trometamol e diferentes aminas como agentes de neutralização, para o tratamento tópico de processos inflamatórios em seres humanos. As formulações farmacêuticas que são o objetivo da presente invenção mostram vantagens oriundas de sua elevada estabilidade ao armazenamento sem alterações acentuadas na aparência do produto com o tempo, bem como de suas baixas atividades alergênicas e foto-alergênicas.
BRPI9810072-6A 1997-06-04 1998-06-04 formulação farmacêutica semi-sólida contendo dexcetoprofen trometamol e processo de preparação da mesma. BR9810072B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701213A ES2124196B1 (es) 1997-06-04 1997-06-04 Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
PCT/EP1998/003333 WO1998055113A1 (en) 1997-06-04 1998-06-04 Semisolid pharmaceutical formulation containing dexketoprofen trometamol

Publications (2)

Publication Number Publication Date
BR9810072A true BR9810072A (pt) 2000-09-19
BR9810072B1 BR9810072B1 (pt) 2010-07-13

Family

ID=8299560

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9810072-6A BR9810072B1 (pt) 1997-06-04 1998-06-04 formulação farmacêutica semi-sólida contendo dexcetoprofen trometamol e processo de preparação da mesma.

Country Status (29)

Country Link
EP (1) EP0996437B1 (pt)
JP (1) JP2002502407A (pt)
KR (1) KR100543558B1 (pt)
CN (1) CN1195510C (pt)
AT (1) ATE201137T1 (pt)
AU (1) AU728442B2 (pt)
BG (1) BG64299B1 (pt)
BR (1) BR9810072B1 (pt)
CA (1) CA2293589C (pt)
CU (1) CU22866A3 (pt)
CZ (1) CZ290118B6 (pt)
DE (1) DE69800804T2 (pt)
DK (1) DK0996437T3 (pt)
EA (1) EA002026B1 (pt)
EC (1) ECSP014108A (pt)
EE (1) EE03905B1 (pt)
ES (2) ES2124196B1 (pt)
GR (1) GR3036319T3 (pt)
HK (1) HK1027753A1 (pt)
HN (1) HN2001000137A (pt)
HU (1) HU226686B1 (pt)
ID (1) ID26240A (pt)
NZ (1) NZ501487A (pt)
PL (1) PL190779B1 (pt)
PT (1) PT996437E (pt)
SK (1) SK284317B6 (pt)
TR (1) TR199903018T2 (pt)
UA (1) UA57075C2 (pt)
WO (1) WO1998055113A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935159A1 (de) * 1999-07-27 2001-02-22 Schuster Wolfgang Mittel zur Muskelentspannung
FR2797766B1 (fr) * 1999-08-27 2003-04-04 Menarini France Nouvelles formes topiques a consistance pateuse sous forme d'un gel distribue en doses
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
EP2764875A1 (en) * 2013-02-06 2014-08-13 Galenicum Health S.L. Process for preparing a stable pharmaceutical composition comprising dexketoprofen trometamol
FR3024360A1 (fr) * 2014-07-30 2016-02-05 Pf Medicament Emulsions aux stearates
RU2667465C2 (ru) * 2015-10-28 2018-09-19 Закрытое Акционерное Общество "Фармфирма "Сотекс" Фармацевтическая композиция для наружного применения, содержащая соль декскетопрофена, и способ ее получения
CN109303762A (zh) * 2017-07-28 2019-02-05 韩美药品株式会社 含有酮洛芬的半固体制剂及其制备方法
KR101935830B1 (ko) * 2018-02-13 2019-01-07 주식회사 오스테오시스 외부역박동시스템과 그 제어방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
IT1124398B (it) * 1979-12-05 1986-05-07 Menarini Sas Utilizzazione della forma farmaceutica gel contenente acido 23 benzoilfenil propionico impiegabile in terapia per uso topico
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
US5091182A (en) * 1990-07-23 1992-02-25 Syntex (U.S.A.) Inc. Dispensing units for ketorolac topical gel formlations
ES2058024B1 (es) * 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.

Also Published As

Publication number Publication date
HN2001000137A (es) 2001-10-29
UA57075C2 (uk) 2003-06-16
ES2124196B1 (es) 1999-12-01
CZ431399A3 (cs) 2000-05-17
CN1259048A (zh) 2000-07-05
EP0996437A1 (en) 2000-05-03
CA2293589C (en) 2008-01-22
HK1027753A1 (en) 2001-01-23
DK0996437T3 (da) 2001-08-06
ATE201137T1 (de) 2001-06-15
HUP0002734A2 (hu) 2001-01-29
AU8624498A (en) 1998-12-21
ECSP014108A (es) 2002-02-25
CZ290118B6 (cs) 2002-06-12
AU728442B2 (en) 2001-01-11
EE9900556A (et) 2000-06-15
SK164999A3 (en) 2000-09-12
ID26240A (id) 2000-12-07
DE69800804D1 (de) 2001-06-21
KR100543558B1 (ko) 2006-01-20
JP2002502407A (ja) 2002-01-22
TR199903018T2 (xx) 2000-05-22
HU226686B1 (en) 2009-06-29
CA2293589A1 (en) 1998-12-10
BG64299B1 (bg) 2004-09-30
KR20010013320A (ko) 2001-02-26
EA199900998A1 (ru) 2000-06-26
ES2124196A1 (es) 1999-01-16
CU22866A3 (es) 2003-08-13
PL337156A1 (en) 2000-07-31
PT996437E (pt) 2001-09-28
DE69800804T2 (de) 2001-09-13
ES2156446T3 (es) 2001-06-16
EP0996437B1 (en) 2001-05-16
BR9810072B1 (pt) 2010-07-13
SK284317B6 (sk) 2005-01-03
EE03905B1 (et) 2002-12-16
BG103926A (en) 2000-09-29
PL190779B1 (pl) 2006-01-31
NZ501487A (en) 2001-06-29
WO1998055113A1 (en) 1998-12-10
HUP0002734A3 (en) 2003-05-28
CN1195510C (zh) 2005-04-06
EA002026B1 (ru) 2001-12-24
GR3036319T3 (en) 2001-11-30

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/07/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 13.07.2020