EA199900998A1 - Полутвердый фармацевтический препарат, содержащий декскетопрофентрометамол - Google Patents

Полутвердый фармацевтический препарат, содержащий декскетопрофентрометамол

Info

Publication number
EA199900998A1
EA199900998A1 EA199900998A EA199900998A EA199900998A1 EA 199900998 A1 EA199900998 A1 EA 199900998A1 EA 199900998 A EA199900998 A EA 199900998A EA 199900998 A EA199900998 A EA 199900998A EA 199900998 A1 EA199900998 A1 EA 199900998A1
Authority
EA
Eurasian Patent Office
Prior art keywords
semi
dexketoprofentrometamol
hand
preparation containing
present
Prior art date
Application number
EA199900998A
Other languages
English (en)
Other versions
EA002026B1 (ru
Inventor
Давид Маулеон Касельяс
Альберт Паломер Бенет
Луиса Гарсиа Перес
Original Assignee
Лабораториос Менарини С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лабораториос Менарини С.А. filed Critical Лабораториос Менарини С.А.
Publication of EA199900998A1 publication Critical patent/EA199900998A1/ru
Publication of EA002026B1 publication Critical patent/EA002026B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Настоящее изобретение относится к способу получения полутвердого фармацевтического препарата (геля или крема), содержащего декскетопрофентрометамол и различные амины в качестве нейтрализующих агентов, для местного лечения воспалительных процессов у людей. Фармацевтические препараты, являющиеся объектом настоящего изобретения, демонстрируют преимущества, являющиеся следствием их высокой стабильности при хранении без заметных изменений во внешнем виде продукта с течением времени, а также следствием их пониженной аллергенной и фотоаллергенной активности.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900998A 1997-06-04 1998-06-04 Полутвердый фармацевтический препарат, содержащий декскетопрофентрометамол EA002026B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701213A ES2124196B1 (es) 1997-06-04 1997-06-04 Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
PCT/EP1998/003333 WO1998055113A1 (en) 1997-06-04 1998-06-04 Semisolid pharmaceutical formulation containing dexketoprofen trometamol

Publications (2)

Publication Number Publication Date
EA199900998A1 true EA199900998A1 (ru) 2000-06-26
EA002026B1 EA002026B1 (ru) 2001-12-24

Family

ID=8299560

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900998A EA002026B1 (ru) 1997-06-04 1998-06-04 Полутвердый фармацевтический препарат, содержащий декскетопрофентрометамол

Country Status (29)

Country Link
EP (1) EP0996437B1 (ru)
JP (1) JP2002502407A (ru)
KR (1) KR100543558B1 (ru)
CN (1) CN1195510C (ru)
AT (1) ATE201137T1 (ru)
AU (1) AU728442B2 (ru)
BG (1) BG64299B1 (ru)
BR (1) BR9810072B1 (ru)
CA (1) CA2293589C (ru)
CU (1) CU22866A3 (ru)
CZ (1) CZ290118B6 (ru)
DE (1) DE69800804T2 (ru)
DK (1) DK0996437T3 (ru)
EA (1) EA002026B1 (ru)
EC (1) ECSP014108A (ru)
EE (1) EE03905B1 (ru)
ES (2) ES2124196B1 (ru)
GR (1) GR3036319T3 (ru)
HK (1) HK1027753A1 (ru)
HN (1) HN2001000137A (ru)
HU (1) HU226686B1 (ru)
ID (1) ID26240A (ru)
NZ (1) NZ501487A (ru)
PL (1) PL190779B1 (ru)
PT (1) PT996437E (ru)
SK (1) SK284317B6 (ru)
TR (1) TR199903018T2 (ru)
UA (1) UA57075C2 (ru)
WO (1) WO1998055113A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935159A1 (de) * 1999-07-27 2001-02-22 Schuster Wolfgang Mittel zur Muskelentspannung
FR2797766B1 (fr) * 1999-08-27 2003-04-04 Menarini France Nouvelles formes topiques a consistance pateuse sous forme d'un gel distribue en doses
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
EP2764875A1 (en) * 2013-02-06 2014-08-13 Galenicum Health S.L. Process for preparing a stable pharmaceutical composition comprising dexketoprofen trometamol
FR3024360A1 (fr) * 2014-07-30 2016-02-05 Pf Medicament Emulsions aux stearates
RU2667465C2 (ru) * 2015-10-28 2018-09-19 Закрытое Акционерное Общество "Фармфирма "Сотекс" Фармацевтическая композиция для наружного применения, содержащая соль декскетопрофена, и способ ее получения
CN109303762A (zh) * 2017-07-28 2019-02-05 韩美药品株式会社 含有酮洛芬的半固体制剂及其制备方法
KR101935830B1 (ko) * 2018-02-13 2019-01-07 주식회사 오스테오시스 외부역박동시스템과 그 제어방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
IT1124398B (it) * 1979-12-05 1986-05-07 Menarini Sas Utilizzazione della forma farmaceutica gel contenente acido 23 benzoilfenil propionico impiegabile in terapia per uso topico
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
US5091182A (en) * 1990-07-23 1992-02-25 Syntex (U.S.A.) Inc. Dispensing units for ketorolac topical gel formlations
ES2058024B1 (es) * 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.

Also Published As

Publication number Publication date
PL337156A1 (en) 2000-07-31
HK1027753A1 (en) 2001-01-23
TR199903018T2 (xx) 2000-05-22
DE69800804D1 (de) 2001-06-21
HU226686B1 (en) 2009-06-29
AU8624498A (en) 1998-12-21
CA2293589A1 (en) 1998-12-10
KR100543558B1 (ko) 2006-01-20
CA2293589C (en) 2008-01-22
BR9810072B1 (pt) 2010-07-13
BG64299B1 (bg) 2004-09-30
ECSP014108A (es) 2002-02-25
SK284317B6 (sk) 2005-01-03
DK0996437T3 (da) 2001-08-06
WO1998055113A1 (en) 1998-12-10
SK164999A3 (en) 2000-09-12
ES2124196A1 (es) 1999-01-16
CN1259048A (zh) 2000-07-05
EP0996437A1 (en) 2000-05-03
PL190779B1 (pl) 2006-01-31
BR9810072A (pt) 2000-09-19
HUP0002734A2 (hu) 2001-01-29
NZ501487A (en) 2001-06-29
KR20010013320A (ko) 2001-02-26
ATE201137T1 (de) 2001-06-15
ES2124196B1 (es) 1999-12-01
JP2002502407A (ja) 2002-01-22
PT996437E (pt) 2001-09-28
EA002026B1 (ru) 2001-12-24
HN2001000137A (es) 2001-10-29
CZ290118B6 (cs) 2002-06-12
UA57075C2 (ru) 2003-06-16
CU22866A3 (es) 2003-08-13
ES2156446T3 (es) 2001-06-16
BG103926A (en) 2000-09-29
ID26240A (id) 2000-12-07
GR3036319T3 (en) 2001-11-30
AU728442B2 (en) 2001-01-11
EE03905B1 (et) 2002-12-16
CZ431399A3 (cs) 2000-05-17
DE69800804T2 (de) 2001-09-13
EE9900556A (et) 2000-06-15
EP0996437B1 (en) 2001-05-16
HUP0002734A3 (en) 2003-05-28
CN1195510C (zh) 2005-04-06

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Designated state(s): AM AZ BY KZ KG MD TJ TM RU