BR9811483A - Derivados do ácido amino-etil-fenóxi-acético e fármacos para a remissão da dor e promover a remoção de cálculos na litìase urinária - Google Patents

Derivados do ácido amino-etil-fenóxi-acético e fármacos para a remissão da dor e promover a remoção de cálculos na litìase urinária

Info

Publication number
BR9811483A
BR9811483A BR9811483-2A BR9811483A BR9811483A BR 9811483 A BR9811483 A BR 9811483A BR 9811483 A BR9811483 A BR 9811483A BR 9811483 A BR9811483 A BR 9811483A
Authority
BR
Brazil
Prior art keywords
remission
phenoxy
pain
ethyl
amino
Prior art date
Application number
BR9811483-2A
Other languages
English (en)
Other versions
BR9811483B1 (pt
Inventor
Tetsuro Tamai
Nobuyuki Tanaka
Hideyuki Muranaka
Harunobu Mukaiyama
Akihito Hibrabayashi
Masaaki Sato
Masuo Akahane
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Publication of BR9811483A publication Critical patent/BR9811483A/pt
Publication of BR9811483B1 publication Critical patent/BR9811483B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"DERIVADOS DO áCIDO AMINO-ETIL-FENóXI-ACéTICO E FáRMACOS PARA A REMISSãO DA DOR E PROMOVER A REMOçãO DE CáLCULOS NA LITìASE URINáRIA" Descreve-se derivados do ácido amino-etil-fenóxi-acético inovadores, representados pela fórmula genérica (I) e seus sais de uso farmacêutico, que têm efeitos de estimular os receptores adrenérgicos ß~ 2~ e ß~ 3~, e são úteis na remissão da dor e promoção da remoção de cálculos na litíase urinária; onde R¹ representa hidrogênio, alquila inferior ou aralquila; R² representa hidrogênio ou halogênio; e os átomos de carbono com as marcas (R) e (S) são aqueles que têm as configurações (R) e (S), respectivamente.
BRPI9811483-2A 1997-07-25 1998-07-15 derivados do Ácido amino-etil-fenàxi-acÉtico e fÁrmacos para a remissço da dor e promover a remoÇço de cÁlculos na litÍase urinÁria. BR9811483B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23323997 1997-07-25
PCT/JP1998/003163 WO1999005090A1 (fr) 1997-07-25 1998-07-15 Derives d'acide aminoethylphenoxyacetique et medicaments qui reduisent la douleur et favorisent la suppression des calculs dans la lithiase urinaire

Publications (2)

Publication Number Publication Date
BR9811483A true BR9811483A (pt) 2000-09-19
BR9811483B1 BR9811483B1 (pt) 2009-01-13

Family

ID=16951956

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9811483-2A BR9811483B1 (pt) 1997-07-25 1998-07-15 derivados do Ácido amino-etil-fenàxi-acÉtico e fÁrmacos para a remissço da dor e promover a remoÇço de cÁlculos na litÍase urinÁria.

Country Status (29)

Country Link
US (1) US6399660B1 (pt)
EP (1) EP1002791B1 (pt)
JP (1) JP4002391B2 (pt)
KR (1) KR100545473B1 (pt)
CN (1) CN1137877C (pt)
AR (1) AR013241A1 (pt)
AT (1) ATE280146T1 (pt)
AU (1) AU754579B2 (pt)
BR (1) BR9811483B1 (pt)
CA (1) CA2298493C (pt)
CO (1) CO4970779A1 (pt)
CZ (1) CZ300389B6 (pt)
DE (1) DE69827137T2 (pt)
ES (1) ES2231996T3 (pt)
HK (1) HK1028016A1 (pt)
HU (1) HUP0004055A3 (pt)
ID (1) ID24062A (pt)
IL (1) IL133863A0 (pt)
MY (1) MY126743A (pt)
NO (1) NO315422B1 (pt)
NZ (1) NZ502366A (pt)
PE (1) PE99899A1 (pt)
PL (1) PL191864B1 (pt)
PT (1) PT1002791E (pt)
RU (1) RU2196130C2 (pt)
SA (1) SA98190661B1 (pt)
TW (1) TW418184B (pt)
WO (1) WO1999005090A1 (pt)
ZA (1) ZA986580B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4212771B2 (ja) 1998-04-14 2009-01-21 キッセイ薬品工業株式会社 ２−メチルプロピオン酸誘導体および当該誘導体を含有する医薬組成物
MY126489A (en) * 1998-07-08 2006-10-31 Kissei Pharmaceutical Phenoxyacetic acid derivatives and medicinal compositions containing the same
DE60024053T2 (de) * 1999-01-21 2006-07-20 Kissei Pharmaceutical Co., Ltd., Matsumoto Kristall-polymorphismus von derivaten der aminoethylphenoxyessigsäure
CA2479254A1 (en) * 2002-03-22 2003-10-02 Kissei Pharmaceutical Co., Ltd. Preventive or therapeutic agent for renal disease
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
DE10333569A1 (de) * 2003-07-23 2005-02-17 Z & J Technologies Gmbh Einrichtung zur Verteilung von Schüttgut in wenigstens zwei oberhalb der Gicht eines Hochofens angeordnete Bunker
JP4843313B2 (ja) * 2004-02-12 2011-12-21 キッセイ薬品工業株式会社 食道の運動障害を伴う疾患の予防または治療用医薬組成物
WO2007004639A1 (ja) * 2005-07-06 2007-01-11 Daiichi Fine Chemical Co., Ltd. 光学活性エリスロ-β-アミノアルコールの製法
AU2006285963A1 (en) * 2005-08-29 2007-03-08 Kissei Pharmaceutical Co., Ltd. Preventive or therapeutic agent for disease caused by decrease in lacrimal fluid
EP1769792A1 (de) * 2005-09-30 2007-04-04 Boehringer Ingelheim Pharma GmbH & Co.KG Verwendung eines beta-3-Adrenozeptor-Agonisten zur Behandlung von Nieren- und Blasenbeschwerden
ES2302447B1 (es) * 2006-10-20 2009-06-12 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
ES2195021T3 (es) * 1995-11-30 2003-12-01 Kissei Pharmaceutical Medicamento para aliviar el dolor y favorecer la eliminacion de calculos en la urolitiasis.
AU4320297A (en) * 1996-09-26 1998-04-17 Kissei Pharmaceutical Co. Ltd. 2-amino-1-(4-hydroxy-2-methylphenyl)propanol derivatives

Also Published As

Publication number Publication date
ATE280146T1 (de) 2004-11-15
EP1002791A1 (en) 2000-05-24
EP1002791B1 (en) 2004-10-20
HUP0004055A2 (hu) 2001-04-28
SA98190661B1 (ar) 2006-09-09
RU2196130C2 (ru) 2003-01-10
KR20010022124A (ko) 2001-03-15
HUP0004055A3 (en) 2001-10-29
AU754579B2 (en) 2002-11-21
CZ2000272A3 (cs) 2000-05-17
PL191864B1 (pl) 2006-07-31
DE69827137T2 (de) 2006-03-09
HK1028016A1 (en) 2001-02-02
ID24062A (id) 2000-07-06
PE99899A1 (es) 1999-11-11
EP1002791A4 (en) 2001-09-12
CN1137877C (zh) 2004-02-11
MY126743A (en) 2006-10-31
AU8241998A (en) 1999-02-16
NO20000371L (no) 2000-01-25
PT1002791E (pt) 2005-01-31
US6399660B1 (en) 2002-06-04
TW418184B (en) 2001-01-11
CO4970779A1 (es) 2000-11-07
BR9811483B1 (pt) 2009-01-13
AR013241A1 (es) 2000-12-13
PL338234A1 (en) 2000-10-09
ZA986580B (en) 1999-02-04
IL133863A0 (en) 2001-04-30
KR100545473B1 (ko) 2006-01-24
ES2231996T3 (es) 2005-05-16
CA2298493C (en) 2008-03-18
DE69827137D1 (de) 2004-11-25
WO1999005090A1 (fr) 1999-02-04
CN1265091A (zh) 2000-08-30
NO20000371D0 (no) 2000-01-25
CA2298493A1 (en) 1999-02-04
JP4002391B2 (ja) 2007-10-31
NZ502366A (en) 2004-12-24
CZ300389B6 (cs) 2009-05-06
NO315422B1 (no) 2003-09-01

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/01/2009, OBSERVADAS AS CONDICOES LEGAIS.

B24B Patent annual fee: requirement for complementing annual fee

Free format text: COMPLEMENTAR A RETRIBUICAO DA(S) 15A. ANUIDADE(S), DE ACORDO COM TABELA VIGENTE, REFERENTE A(S) GUIA(S) DE RECOLHIMENTO 92120559216-3.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24D Patent annual fee: restoration after fee payment
B21H Decision of lapse of a patent or of a certificate of addition of invention cancelled [chapter 21.8 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)