BR9808466A - Método para distribuição oral de proteìnas - Google Patents
Método para distribuição oral de proteìnasInfo
- Publication number
- BR9808466A BR9808466A BR9808466-6A BR9808466A BR9808466A BR 9808466 A BR9808466 A BR 9808466A BR 9808466 A BR9808466 A BR 9808466A BR 9808466 A BR9808466 A BR 9808466A
- Authority
- BR
- Brazil
- Prior art keywords
- protein distribution
- composition
- oral protein
- oral
- hydrogel matrix
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4228097P | 1997-04-02 | 1997-04-02 | |
US6136797P | 1997-10-08 | 1997-10-08 | |
PCT/US1998/006563 WO1998043615A1 (en) | 1997-04-02 | 1998-04-02 | Method for oral delivery of proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9808466A true BR9808466A (pt) | 2001-08-07 |
Family
ID=26719055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9808466-6A BR9808466A (pt) | 1997-04-02 | 1998-04-02 | Método para distribuição oral de proteìnas |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0975328A1 (sh) |
JP (1) | JP2002512607A (sh) |
KR (1) | KR20010005952A (sh) |
CN (1) | CN1259045A (sh) |
AU (1) | AU727053B2 (sh) |
BR (1) | BR9808466A (sh) |
CA (1) | CA2285457A1 (sh) |
IL (1) | IL132176A0 (sh) |
NO (1) | NO994757L (sh) |
NZ (1) | NZ500075A (sh) |
PL (1) | PL335974A1 (sh) |
TR (1) | TR199903240T2 (sh) |
WO (1) | WO1998043615A1 (sh) |
YU (1) | YU49699A (sh) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
DE10040592A1 (de) * | 2000-08-15 | 2002-03-07 | Aventis Res & Tech Gmbh & Co | Formulierung zur verbesserten Aufnahme von Wirkstoffen und deren Verwendung |
US6878384B2 (en) | 2001-03-13 | 2005-04-12 | Microvention, Inc. | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
EP1494732B1 (en) | 2002-03-20 | 2008-01-30 | MannKind Corporation | Inhalation apparatus |
KR101273120B1 (ko) | 2004-08-20 | 2013-06-13 | 맨카인드 코포레이션 | 다이케토피페라진 합성의 촉매 작용 |
KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
US8110212B2 (en) | 2005-04-07 | 2012-02-07 | Drexel University | Bioactive thermogelling polymer systems and methods of their use |
EP1916995B2 (en) | 2005-07-29 | 2022-06-29 | Stichting Groningen Centre for Drug Research | Ph-controlled pulsatile delivery system, methods for preparation and use thereof |
WO2007016600A2 (en) * | 2005-08-01 | 2007-02-08 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
IN2014DN09128A (sh) | 2005-09-14 | 2015-07-10 | Mannkind Corp | |
BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
EP2389960B1 (en) | 2006-06-15 | 2018-02-28 | MicroVention, Inc. | Environmentally responsive hydrogel |
US8470035B2 (en) | 2007-12-21 | 2013-06-25 | Microvention, Inc. | Hydrogel filaments for biomedical uses |
CN109568740B (zh) | 2008-06-13 | 2022-05-27 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
ES2904623T3 (es) | 2008-06-20 | 2022-04-05 | Mannkind Corp | Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
US10639396B2 (en) | 2015-06-11 | 2020-05-05 | Microvention, Inc. | Polymers |
KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
HUP0900482A2 (en) | 2009-08-03 | 2011-03-28 | Cera Med Kft | Pharmaceutical formulation for oral administration |
KR20120090052A (ko) | 2009-09-24 | 2012-08-16 | 마이크로벤션, 인코포레이티드 | 생물 의학적 사용을 위한 주사가능한 히드로겔 필라멘트 |
JP5722333B2 (ja) | 2009-10-26 | 2015-05-20 | マイクロベンション インコーポレイテッド | 膨張性ポリマーで構成される塞栓形成デバイス |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
KR20130117755A (ko) | 2010-06-21 | 2013-10-28 | 맨카인드 코포레이션 | 건조 분말 약물 운반 시스템 및 방법 |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
US9456823B2 (en) | 2011-04-18 | 2016-10-04 | Terumo Corporation | Embolic devices |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
US9011884B2 (en) | 2012-04-18 | 2015-04-21 | Microvention, Inc. | Embolic devices |
AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
ES2754388T3 (es) | 2013-03-15 | 2020-04-17 | Mannkind Corp | Composiciones y métodos de dicetopiperazina microcristalina |
BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
WO2015021044A1 (en) * | 2013-08-05 | 2015-02-12 | University Of Rochester | Compositions and methods for stimuli-responsive release of a therapeutic agent |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10124090B2 (en) | 2014-04-03 | 2018-11-13 | Terumo Corporation | Embolic devices |
WO2015167751A1 (en) | 2014-04-29 | 2015-11-05 | Microvention, Inc. | Polymers |
CN110433326A (zh) | 2014-04-29 | 2019-11-12 | 微仙美国有限公司 | 包含活性剂的聚合物 |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
US10265405B2 (en) | 2014-11-18 | 2019-04-23 | Board Of Regents, The University Of Texas System | Polymers for delivery of factor VIII and/or factor IX |
WO2024130101A1 (en) * | 2022-12-16 | 2024-06-20 | Wake Forest University Health Sciences | Hydrogel compositions and methods of making and using the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2976576A (en) * | 1956-04-24 | 1961-03-28 | Wichterle Otto | Process for producing shaped articles from three-dimensional hydrophilic high polymers |
US3220960A (en) * | 1960-12-21 | 1965-11-30 | Wichterle Otto | Cross-linked hydrophilic polymers and articles made therefrom |
DE1617393C2 (de) * | 1966-01-06 | 1982-11-11 | Československá akademie věd, Praha | Verfahren zur Herstellung von biologisch aktive Stoffe enthaltenden hydrophilen vernetzten Copolymeren |
US3607848A (en) * | 1967-08-07 | 1971-09-21 | Ceskoslovenska Akademie Ved | Method for preparing insoluble,cross-linked organic hydrogels comprising copolymers of glycol monoesters with diesters |
US3885078A (en) * | 1968-03-06 | 1975-05-20 | Ceskoslovenska Akademie Ved | Hydrogel laminates and method of manufacturing thereof |
US4071508A (en) * | 1975-02-11 | 1978-01-31 | Plastomedical Sciences, Inc. | Anionic hydrogels based on hydroxyalkyl acrylates and methacrylates |
FR2601026B1 (fr) * | 1986-04-15 | 1988-09-16 | Rhone Poulenc Chimie | Matiere seche hydratable en un gel aqueux contenant des particules de polymeres dispersees, procede pour sa preparation et son application en biologie |
-
1998
- 1998-04-02 WO PCT/US1998/006563 patent/WO1998043615A1/en not_active Application Discontinuation
- 1998-04-02 KR KR1019997009029A patent/KR20010005952A/ko not_active Application Discontinuation
- 1998-04-02 TR TR1999/03240T patent/TR199903240T2/xx unknown
- 1998-04-02 PL PL98335974A patent/PL335974A1/xx unknown
- 1998-04-02 EP EP98914454A patent/EP0975328A1/en not_active Withdrawn
- 1998-04-02 CA CA002285457A patent/CA2285457A1/en not_active Abandoned
- 1998-04-02 CN CN98805351A patent/CN1259045A/zh active Pending
- 1998-04-02 NZ NZ500075A patent/NZ500075A/xx unknown
- 1998-04-02 IL IL13217698A patent/IL132176A0/xx unknown
- 1998-04-02 AU AU68809/98A patent/AU727053B2/en not_active Ceased
- 1998-04-02 JP JP54201598A patent/JP2002512607A/ja active Pending
- 1998-04-02 YU YU49699A patent/YU49699A/sh unknown
- 1998-04-02 BR BR9808466-6A patent/BR9808466A/pt not_active IP Right Cessation
-
1999
- 1999-09-30 NO NO994757A patent/NO994757L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO994757D0 (no) | 1999-09-30 |
NO994757L (no) | 1999-11-29 |
AU727053B2 (en) | 2000-11-30 |
CN1259045A (zh) | 2000-07-05 |
CA2285457A1 (en) | 1998-10-08 |
YU49699A (sh) | 2002-12-10 |
JP2002512607A (ja) | 2002-04-23 |
NZ500075A (en) | 2001-03-30 |
IL132176A0 (en) | 2001-03-19 |
AU6880998A (en) | 1998-10-22 |
TR199903240T2 (xx) | 2000-05-22 |
PL335974A1 (en) | 2000-06-05 |
KR20010005952A (ko) | 2001-01-15 |
WO1998043615A1 (en) | 1998-10-08 |
EP0975328A1 (en) | 2000-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A, 8A E 9A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1889 DE 20/03/2007. |