BR9808109A - Inibidor terapêutico de células vasculares da musculatura lisa - Google Patents

Inibidor terapêutico de células vasculares da musculatura lisa

Info

Publication number
BR9808109A
BR9808109A BR9808109-8A BR9808109A BR9808109A BR 9808109 A BR9808109 A BR 9808109A BR 9808109 A BR9808109 A BR 9808109A BR 9808109 A BR9808109 A BR 9808109A
Authority
BR
Brazil
Prior art keywords
therapeutic
inhibitor
smooth muscle
vascular
vascular cell
Prior art date
Application number
BR9808109-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Lawrence L Kunz
Richard A Klein
John M Reno
Original Assignee
Neorx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27125289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9808109(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/829,991 external-priority patent/US6306421B1/en
Priority claimed from US08/829,685 external-priority patent/US5981568A/en
Application filed by Neorx Corp filed Critical Neorx Corp
Publication of BR9808109A publication Critical patent/BR9808109A/pt

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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/63—Crystals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR9808109-8A 1997-03-31 1998-03-31 Inibidor terapêutico de células vasculares da musculatura lisa BR9808109A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/829,991 US6306421B1 (en) 1992-09-25 1997-03-31 Therapeutic inhibitor of vascular smooth muscle cells
US08/829,685 US5981568A (en) 1993-01-28 1997-03-31 Therapeutic inhibitor of vascular smooth muscle cells
PCT/US1998/006322 WO1998043618A2 (en) 1997-03-31 1998-03-31 Use of cytoskeletal inhibitors for the prevention of restenosis

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JP (1) JP2001521503A (https=)
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BR (1) BR9808109A (https=)
CA (1) CA2285389C (https=)
DE (1) DE69826847T3 (https=)
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WO1998043618A9 (en) 1999-04-22
WO1998043618A3 (en) 1998-11-05
ATE278397T1 (de) 2004-10-15
DE69826847D1 (de) 2004-11-11
JP2001521503A (ja) 2001-11-06
EP2292225A1 (en) 2011-03-09
EP2292225B1 (en) 2012-05-09
EP0975340B2 (en) 2009-10-28
EP1512398A1 (en) 2005-03-09
EP2292225B9 (en) 2012-06-27
ES2226120T3 (es) 2005-03-16
ES2388248T3 (es) 2012-10-11
WO1998043618A2 (en) 1998-10-08
DE69826847T3 (de) 2010-05-12
EP0975340B1 (en) 2004-10-06
DE69826847T2 (de) 2006-04-13
CA2285389C (en) 2008-12-30
EP0975340A2 (en) 2000-02-02
CA2285389A1 (en) 1998-10-08

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