BR9803318A - Composto indol e indazol, um processo para a sua preparação e composição farmacêutica contendo os mesmos. - Google Patents

Composto indol e indazol, um processo para a sua preparação e composição farmacêutica contendo os mesmos.

Info

Publication number
BR9803318A
BR9803318A BR9803318-2A BR9803318A BR9803318A BR 9803318 A BR9803318 A BR 9803318A BR 9803318 A BR9803318 A BR 9803318A BR 9803318 A BR9803318 A BR 9803318A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical composition
composition containing
indole
indazole compound
Prior art date
Application number
BR9803318-2A
Other languages
English (en)
Inventor
Gilbert Lavielle
Olivier Muller
Christine Vayssettes-Courchay
Jean-Jacques Descombes
Tony Verbeuren
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of BR9803318A publication Critical patent/BR9803318A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção:<B>"COMPOSTO INDOL E INDAZOL, UM PROCESSO PARA SUA PREPARAçãO E COMPOSIçãO FARMACêUTICA CONTENDO OS MESMOS"<D>. Composto de fórmula (I): onde: - n é 0 ou 1, - A representa uma ligação <sym>ou um grupo alquileno ou alquenileno, - X representa um átomo de nitrogênio ou um grupo C-R2, - R~ 1~ representa um átomo de hidrogênio ou um grupo alquila, - G~ 1~ representa qualquer um dos grupos definidos na descrição. Medicamentos.
BR9803318-2A 1997-09-03 1998-09-01 Composto indol e indazol, um processo para a sua preparação e composição farmacêutica contendo os mesmos. BR9803318A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710939A FR2767827A1 (fr) 1997-09-03 1997-09-03 Nouveaux derives de l'indole et de l'indazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR9803318A true BR9803318A (pt) 2000-02-08

Family

ID=9510710

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9803318-2A BR9803318A (pt) 1997-09-03 1998-09-01 Composto indol e indazol, um processo para a sua preparação e composição farmacêutica contendo os mesmos.

Country Status (20)

Country Link
US (2) US6020336A (pt)
EP (1) EP0902027B1 (pt)
JP (1) JPH11130773A (pt)
CN (2) CN1510034A (pt)
AT (1) ATE203531T1 (pt)
AU (1) AU736602B2 (pt)
BR (1) BR9803318A (pt)
CA (1) CA2246485C (pt)
DE (1) DE69801196T2 (pt)
DK (1) DK0902027T5 (pt)
ES (1) ES2162404T3 (pt)
FR (1) FR2767827A1 (pt)
GR (1) GR3036678T3 (pt)
HK (1) HK1019738A1 (pt)
HU (1) HUP9801977A1 (pt)
NO (1) NO316271B1 (pt)
NZ (1) NZ331683A (pt)
PL (1) PL328323A1 (pt)
PT (1) PT902027E (pt)
ZA (1) ZA988072B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU779073B2 (en) * 1998-12-23 2005-01-06 Nps Allelix Corp. Indole and indolizidine derivatives for the treatment of migraine
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
HN2001000008A (es) 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
EP1274706A1 (en) 2000-04-18 2003-01-15 Agouron Pharmaceuticals, Inc. Pyrazoles for inhibiting protein kinases
DK1309591T3 (da) 2000-08-14 2007-03-26 Ortho Mcneil Pharm Inc Substituerede pyrazoler
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
US20070105841A1 (en) * 2000-08-14 2007-05-10 Breitenbucher J G Method for treating allergies using substituted pyrazoles
FR2829134B1 (fr) 2001-08-28 2006-11-24 Atofina Procede de preparation de (meth) acrylates d'alkylimidazolidone
US20030073672A1 (en) * 2001-09-05 2003-04-17 Breitenbucher J. Guy Method for treating allergies using substituted pyrazoles
WO2012086735A1 (ja) * 2010-12-22 2012-06-28 大正製薬株式会社 縮合複素環化合物
CN102617548A (zh) * 2011-01-31 2012-08-01 北京赛林泰医药技术有限公司 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
EP3116504A4 (en) * 2014-03-10 2017-08-09 Innov17 LLC Retinoic acid receptor-related orphan receptor modulators and uses thereof
US20150252051A1 (en) * 2014-03-10 2015-09-10 Innov17 Llc Retinoic acid receptor-related orphan receptor modulators and uses thereof
US11459308B2 (en) 2016-12-05 2022-10-04 Microbiotix, Inc. Broad spectrum inhibitors of filoviruses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
TW203049B (pt) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
WO1993020065A1 (en) * 1992-03-27 1993-10-14 Kyoto Pharmaceutical Industries, Ltd. Novel imidazole derivative, pharmaceutical use thereof, and intermediate therefor
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
GB9402016D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
GB2289465A (en) * 1994-05-19 1995-11-22 Merck Sharp & Dohme Five-membered heteroaromatic 5-HT receptor agonists
JPH10501212A (ja) * 1994-05-19 1998-02-03 メルク シヤープ エンド ドーム リミテツド ５−ｈｔ▲下１ｄ▼−アルファ作働薬としてのインドール−３−イルアルキルのピペラジン、ピペリジンおよびテトラヒドロピリジン誘導体
WO1996004274A1 (en) * 1994-08-02 1996-02-15 Merck Sharp & Dohme Limited Azetidine, pyrrolidine and piperidine derivatives
ZA965837B (en) * 1995-07-11 1997-01-31 Merck & Co Inc A triazolylmethyl-indole ethylamine bisulfate salt
AU707750B2 (en) * 1995-08-07 1999-07-22 Merck Sharp & Dohme Limited Substituted 1-indolylpropyl-4-phenethylpiperazine derivatives

Also Published As

Publication number Publication date
US6020336A (en) 2000-02-01
ATE203531T1 (de) 2001-08-15
EP0902027A1 (fr) 1999-03-17
DK0902027T5 (da) 2001-12-03
EP0902027B1 (fr) 2001-07-25
ES2162404T3 (es) 2001-12-16
DK0902027T3 (da) 2001-10-15
PT902027E (pt) 2001-11-30
CA2246485A1 (fr) 1999-03-03
DE69801196D1 (de) 2001-08-30
CN1218052A (zh) 1999-06-02
NO984033L (no) 1999-03-04
AU736602B2 (en) 2001-08-02
GR3036678T3 (en) 2001-12-31
HU9801977D0 (en) 1998-10-28
NO316271B1 (no) 2004-01-05
CA2246485C (fr) 2004-04-20
NZ331683A (en) 2000-01-28
HK1019738A1 (en) 2000-02-25
CN1087741C (zh) 2002-07-17
CN1510034A (zh) 2004-07-07
HUP9801977A1 (hu) 2000-11-28
JPH11130773A (ja) 1999-05-18
US6046205A (en) 2000-04-04
ZA988072B (en) 1999-03-09
NO984033D0 (no) 1998-09-02
PL328323A1 (en) 1999-03-15
DE69801196T2 (de) 2002-03-14
FR2767827A1 (fr) 1999-02-26
AU8306898A (en) 1999-03-18

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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