HK1019738A1 - New indole and indazole compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New indole and indazole compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HK1019738A1
HK1019738A1 HK99104871A HK99104871A HK1019738A1 HK 1019738 A1 HK1019738 A1 HK 1019738A1 HK 99104871 A HK99104871 A HK 99104871A HK 99104871 A HK99104871 A HK 99104871A HK 1019738 A1 HK1019738 A1 HK 1019738A1
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
indazole
compositions containing
disorders
Prior art date
Application number
HK99104871A
Other languages
English (en)
Inventor
Gilbert Lavielle
Olivier Muller
Christine Vayssettes-Courchay
Jean-Jacques Descombes
Tony Verbeuren
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1019738A1 publication Critical patent/HK1019738A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK99104871A 1997-09-03 1999-10-28 New indole and indazole compounds, a process for their preparation and pharmaceutical compositions containing them HK1019738A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710939A FR2767827A1 (fr) 1997-09-03 1997-09-03 Nouveaux derives de l'indole et de l'indazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
HK1019738A1 true HK1019738A1 (en) 2000-02-25

Family

ID=9510710

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99104871A HK1019738A1 (en) 1997-09-03 1999-10-28 New indole and indazole compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (2) US6020336A (xx)
EP (1) EP0902027B1 (xx)
JP (1) JPH11130773A (xx)
CN (2) CN1087741C (xx)
AT (1) ATE203531T1 (xx)
AU (1) AU736602B2 (xx)
BR (1) BR9803318A (xx)
CA (1) CA2246485C (xx)
DE (1) DE69801196T2 (xx)
DK (1) DK0902027T5 (xx)
ES (1) ES2162404T3 (xx)
FR (1) FR2767827A1 (xx)
GR (1) GR3036678T3 (xx)
HK (1) HK1019738A1 (xx)
HU (1) HUP9801977A1 (xx)
NO (1) NO316271B1 (xx)
NZ (1) NZ331683A (xx)
PL (1) PL328323A1 (xx)
PT (1) PT902027E (xx)
ZA (1) ZA988072B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU779073B2 (en) * 1998-12-23 2005-01-06 Nps Allelix Corp. Indole and indolizidine derivatives for the treatment of migraine
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
HN2001000008A (es) 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
MXPA02010222A (es) 2000-04-18 2003-05-23 Agouron Pharma Pirazoles para inhibir proteina cinasa.
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
US20070105841A1 (en) * 2000-08-14 2007-05-10 Breitenbucher J G Method for treating allergies using substituted pyrazoles
AU8125501A (en) 2000-08-14 2002-02-25 Ortho Mcneil Pharm Inc Substituted pyrazoles
FR2829134B1 (fr) 2001-08-28 2006-11-24 Atofina Procede de preparation de (meth) acrylates d'alkylimidazolidone
US20030073672A1 (en) * 2001-09-05 2003-04-17 Breitenbucher J. Guy Method for treating allergies using substituted pyrazoles
WO2012086735A1 (ja) * 2010-12-22 2012-06-28 大正製薬株式会社 縮合複素環化合物
CN102617548A (zh) * 2011-01-31 2012-08-01 北京赛林泰医药技术有限公司 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
WO2014102588A2 (en) * 2012-12-27 2014-07-03 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US20150252051A1 (en) * 2014-03-10 2015-09-10 Innov17 Llc Retinoic acid receptor-related orphan receptor modulators and uses thereof
US20150252022A1 (en) * 2014-03-10 2015-09-10 Innov17 Llc Retinoic acid receptor-related orphan receptor modulators and uses thereof
WO2018106667A1 (en) * 2016-12-05 2018-06-14 Microbiotix, Inc. Broad-spectrum inhibitors of filoviruses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
TW203049B (xx) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
EP0597112A4 (en) * 1992-03-27 1994-06-22 Kyoto Pharma Ind Novel imidazole derivative, pharmaceutical use thereof, and intermediate therefor.
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
GB9402016D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
GB2289465A (en) * 1994-05-19 1995-11-22 Merck Sharp & Dohme Five-membered heteroaromatic 5-HT receptor agonists
AU694226B2 (en) * 1994-05-19 1998-07-16 Merck Sharp & Dohme Limited Piperazine, piperidine and tetrahydropyridine derivatives ofindol-3-ylalkyl as 5-HT1D-alpha agonists
EP0804434A1 (en) * 1994-08-02 1997-11-05 MERCK SHARP & DOHME LTD. Azetidine, pyrrolidine and piperidine derivatives
ZA965837B (en) * 1995-07-11 1997-01-31 Merck & Co Inc A triazolylmethyl-indole ethylamine bisulfate salt
WO1997006159A1 (en) * 1995-08-07 1997-02-20 Merck Sharp & Dohme Limited Substituted 1-indolylpropyl-4-phenethylpiperazine derivatives

Also Published As

Publication number Publication date
ATE203531T1 (de) 2001-08-15
GR3036678T3 (en) 2001-12-31
EP0902027B1 (fr) 2001-07-25
NZ331683A (en) 2000-01-28
FR2767827A1 (fr) 1999-02-26
ZA988072B (en) 1999-03-09
CN1218052A (zh) 1999-06-02
HU9801977D0 (en) 1998-10-28
US6046205A (en) 2000-04-04
DE69801196T2 (de) 2002-03-14
US6020336A (en) 2000-02-01
EP0902027A1 (fr) 1999-03-17
HUP9801977A1 (hu) 2000-11-28
DK0902027T5 (da) 2001-12-03
NO984033D0 (no) 1998-09-02
CN1087741C (zh) 2002-07-17
CA2246485C (fr) 2004-04-20
NO316271B1 (no) 2004-01-05
CA2246485A1 (fr) 1999-03-03
BR9803318A (pt) 2000-02-08
ES2162404T3 (es) 2001-12-16
PL328323A1 (en) 1999-03-15
JPH11130773A (ja) 1999-05-18
PT902027E (pt) 2001-11-30
DK0902027T3 (da) 2001-10-15
NO984033L (no) 1999-03-04
AU8306898A (en) 1999-03-18
DE69801196D1 (de) 2001-08-30
AU736602B2 (en) 2001-08-02
CN1510034A (zh) 2004-07-07

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060902