BR9710355A - Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal. - Google Patents

Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.

Info

Publication number
BR9710355A
BR9710355A BR9710355-1A BR9710355A BR9710355A BR 9710355 A BR9710355 A BR 9710355A BR 9710355 A BR9710355 A BR 9710355A BR 9710355 A BR9710355 A BR 9710355A
Authority
BR
Brazil
Prior art keywords
virus
mammal
compositions
hepatitis
hiv
Prior art date
Application number
BR9710355-1A
Other languages
English (en)
Inventor
Hsiu-Hsien Tsai
Shie Ming Hwang
Original Assignee
Hsiu Hsien Tsai E Shi Ming Hwa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hsiu Hsien Tsai E Shi Ming Hwa filed Critical Hsiu Hsien Tsai E Shi Ming Hwa
Priority claimed from PCT/US1997/012293 external-priority patent/WO1998001144A2/en
Publication of BR9710355A publication Critical patent/BR9710355A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSIçãO úTIL PARA O TRATAMENTO DE INFECçõES VIRAIS EM UM MAMìFERO, PROCESSO PARA TRATAR UMA INFECçãO VIRAL EM UM MAMìFERO, E, PRODUTO MEDICINAL". Esta invenção refere-se às composições derivadas de medicamentos herbáceos chineses, às plantas medicinais e ao seu uso para o tratamento de animais infectados com vírus da hepatite B (HBV), vírus da hepatite C (HCV) e vírus da imunodeficiência humana (HIV). Mais especificamente, as composições da presente invenção são derivadas de vários medicamentos herbáceos chineses que apresentam uma longa história de consumo humano. As composições da invenção são obtidas através de técnicas específicas e têm demonstrado eficácia notável no tratamento de portadores de HBV humano e pacientes com hepatite C. Composições de acordo com a invenção também têm exibido atividades antivirais in vitro contra vírus da leucemia de murídeos (MuLV) e HIV. HIV é o vírus conhecido por causar a síndrome da imunodeficiência adquirida (AIDS) em humanos e AIDS apresenta problemas especiais à comunidade médica que são solucionados pela presente invenção.
BR9710355-1A 1996-07-09 1997-07-09 Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal. BR9710355A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1610096P 1996-07-09 1996-07-09
US2146796P 1996-07-10 1996-07-10
PCT/US1997/012293 WO1998001144A2 (en) 1996-07-09 1997-07-09 Antiviral agents from plant extracts and use for treatment of viral infections

Publications (1)

Publication Number Publication Date
BR9710355A true BR9710355A (pt) 2000-01-11

Family

ID=26688168

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710355-1A BR9710355A (pt) 1996-07-09 1997-07-09 Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.

Country Status (11)

Country Link
US (3) US5837257A (pt)
EP (1) EP0914139B1 (pt)
JP (1) JP2001516337A (pt)
KR (1) KR100511514B1 (pt)
AT (1) ATE387208T1 (pt)
AU (1) AU742854B2 (pt)
BR (1) BR9710355A (pt)
CA (1) CA2271622C (pt)
DE (1) DE69738535T2 (pt)
ES (1) ES2303342T3 (pt)
NZ (1) NZ333707A (pt)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100346609B1 (ko) * 1994-12-28 2002-11-18 주식회사 엘지씨아이 금은화로부터세코노가노사이드를추출하는방법
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections
KR100239879B1 (ko) * 1997-11-05 2000-02-01 김상조 간암 예방 및 치료용 생약제
US6524625B2 (en) * 1998-06-30 2003-02-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyuto Physiologically active extract obtained from indigo plant polygonum tinctorium
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
AU3548900A (en) * 1999-04-14 2000-11-14 Max Zeller & Sohne Ag Medicament for inhibiting NF-kappaB
JP2003504347A (ja) * 1999-07-13 2003-02-04 フン アーン、デウク 生薬剤を用いた女性用生理ナプキン塗布用組成物
CA2380924C (en) 1999-08-13 2008-02-19 University Of Maryland Biotechnology Institute Compositions for treating viral infections, and methods therefor
US6103242A (en) * 1999-10-21 2000-08-15 Buckley; William Method of controlling blood sugar levels using Coccoloba uvifera
CN1173965C (zh) * 2000-03-30 2004-11-03 科学与工业研究会 从植物黄花蒿中分离化合物东莨菪亭的方法
AU2001261744A1 (en) * 2000-05-19 2001-12-03 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
US7045159B1 (en) 2000-09-19 2006-05-16 Rutgers, The State University Of New Jersey Antiviral substances from plant cuticular and epiciticular material
US6696094B2 (en) * 2000-10-18 2004-02-24 Tzu-Sheng Wu Herbal pharmaceutical composition for treatment of HIV/AIDS patients
US6455078B1 (en) * 2000-10-18 2002-09-24 Tzu-Sheng Wu Medicinal herbal composition for treating liver diseases and HIV
CN1309399C (zh) * 2000-10-25 2007-04-11 国家中药制药工程技术研究中心 复方双黄连制剂及制备方法
WO2002044717A1 (en) * 2000-12-01 2002-06-06 Cornell Research Foundation Animal model for flaviviridae infection
JP4880816B2 (ja) * 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
US6455070B1 (en) 2001-02-15 2002-09-24 East Park Research, Inc. Composition for treating symptoms of influenza
CN1220498C (zh) * 2001-04-02 2005-09-28 李洪芬 一种治疗哮喘的药剂
US20030054047A1 (en) * 2001-06-15 2003-03-20 Sanjiu Medical & Pharmaceutical Co., Ltd. Pharmaceutical composition for the treatment of viral infection
WO2003020260A1 (en) * 2001-08-31 2003-03-13 Metaproteomics, Llc Arginine compositions for coordinate modification of multiple cardiovascular risk factors
WO2003026589A2 (en) * 2001-09-28 2003-04-03 Idenix (Cayman) Limited Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
WO2003030635A1 (en) * 2001-10-11 2003-04-17 Natural Remedies Private Limited A herbal hepatoprotective and weight gain promoter and a process thereof
US6541045B1 (en) * 2002-01-04 2003-04-01 Nutraceutical Corporation Herbal composition and method for combating inflammation
PT1523489E (pt) 2002-06-28 2014-06-24 Centre Nat Rech Scient Profármacos de nucleósido modificado em 2' e 3' para tratamento de infecções por flaviridae
AU2003244587B2 (en) * 2002-07-12 2009-06-25 Academia Sinica Use of Anoectochilus Formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
US7033617B2 (en) * 2002-07-12 2006-04-25 Academia Sinica Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
BR0313164A (pt) * 2002-08-01 2007-07-17 Pharmasset Inc compostos com o sistema biciclo[4.2.1] nonano para o tratamento de infecções por flaviviridae
US20040151787A1 (en) * 2002-11-21 2004-08-05 Pero Ronald W. Water soluble compositions derived from plant material and preparation thereof
US20040126351A1 (en) * 2002-12-26 2004-07-01 Avon Products, Inc. Topical composition having natural skin anti-irritant ingredient and method of use
WO2004064759A2 (en) * 2003-01-21 2004-08-05 Chiron Corporation Use of tryptanthrin compounds for immune potentiation
TWI269656B (en) * 2003-03-05 2007-01-01 Original Image Co Ltd Therapeutical composition for hepatitis C
KR101000953B1 (ko) * 2003-05-16 2010-12-13 안경민 비수리 추출물 및 그 용도
US20040234546A1 (en) * 2003-05-19 2004-11-25 Amazon Biotech Inc. Treatments using an herbal composition
US7160561B2 (en) 2003-05-19 2007-01-09 Amazon Biotech Inc. Herbal composition and method of treating HIV infection
PL3521297T3 (pl) 2003-05-30 2022-04-04 Gilead Pharmasset Llc Zmodyfikowane fluorowane analogi nukleozydów
TWI315200B (en) * 2003-06-13 2009-10-01 Ind Tech Res Inst An herbal extract having anti-enterovirus activity and preparation of same
US7648717B2 (en) * 2003-06-13 2010-01-19 Industrial Technology Research Institute Herbal extract having anti-virus activity and preparation of same
WO2005009418A2 (en) * 2003-07-25 2005-02-03 Idenix (Cayman) Limited Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis c
FR2859107B1 (fr) * 2003-08-26 2008-04-18 Oyoubi Pierre Pyebi Utilisation des extraits d'une graminee, d'une rutacee et d'une pieridophyte dans une composition pharmaceutique a activite antivirale, antibacterienne, antifongique et aussi destinee a stimuler les defenses immunitaires
GB0500020D0 (en) 2005-01-04 2005-02-09 Novartis Ag Organic compounds
CN1330359C (zh) * 2004-04-09 2007-08-08 北京琦杰源医药科技发展有限公司 一种治疗艾滋病的中药制剂及其加工方法
SE0400996D0 (sv) * 2004-04-16 2004-04-16 Alltech Ireland Inc Use of plants, plant extracts and nature-identical components from plants to affect the rumen fermentation and to improve the energy and protein retention of ruminants
CN101023094B (zh) 2004-07-21 2011-05-18 法莫赛特股份有限公司 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
US20060154904A1 (en) * 2004-09-10 2006-07-13 Cornell Research Foundation, Inc. Betulinol derivatives as anti-HIV agents
WO2006031725A2 (en) 2004-09-14 2006-03-23 Pharmasset, Inc. Preparation of 2'­fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
US20060110479A1 (en) * 2004-11-24 2006-05-25 Mitra Shankar K Natural composition for curing hepatitis-B, methods for making the same and pharmaceutical formulations thereof
US7615240B2 (en) * 2005-01-07 2009-11-10 Auburn University Method and composition for the control of gastrointestinal parasites in animals
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
US7556830B2 (en) * 2005-08-22 2009-07-07 International Patents Holdings, Ltd. Medicinal herbal composition for treating infection
DE202005015707U1 (de) * 2005-10-06 2006-04-20 Sheng Foong Pharmaceutical Co. Ltd., Su-Ao Chen Kräuterzusammensetzung zur Behandlung von Krebs
TWI370739B (en) * 2005-12-30 2012-08-21 Ind Tech Res Inst Herbal compositions of inhibiting free radicals
US8980336B2 (en) * 2005-12-30 2015-03-17 Industrial Technology Research Institute Method for inhibiting free radicals
MX2008013119A (es) 2006-04-11 2008-10-21 Novartis Ag Inhibidores de hcv/vih y sus usos.
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US20080057111A1 (en) * 2006-08-29 2008-03-06 Lixian Jiang Herbal composition for flu prevention and treatment
WO2008088806A1 (en) * 2007-01-16 2008-07-24 Johns Hopkins University Combinational paradigm combating hiv, hiv/hsv, or hiv/hpv infections in humans using small molecular weight compounds from plants
CA2696053A1 (en) 2007-02-28 2008-09-04 Conatus Pharmaceuticals, Inc. Methods for the treatment of liver diseases
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US20090053335A1 (en) * 2007-04-13 2009-02-26 Chih-Hui Lin Herbal compositions for the inhibition of human immunodeficiency virus (hiv)
US20080254148A1 (en) * 2007-04-13 2008-10-16 Gerent Biotech Co. Herbal compositions for the inhibition of human immunodeficiency virus
US8067401B2 (en) * 2007-09-06 2011-11-29 International Patent Holdings Llc Compounds and compositions for treating infection
CA2698747A1 (en) * 2007-09-07 2009-03-12 Bionovo, Inc. Estrogenic extracts of scuttelaria barbata d. don of the labiatae family and uses thereof
TW200946541A (en) * 2008-03-27 2009-11-16 Idenix Pharmaceuticals Inc Solid forms of an anti-HIV phosphoindole compound
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010014134A1 (en) 2008-07-02 2010-02-04 Idenix Pharamaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
EP2376514A2 (en) 2008-12-23 2011-10-19 Pharmasset, Inc. Nucleoside analogs
CL2009002206A1 (es) 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
NZ593648A (en) 2008-12-23 2013-09-27 Gilead Pharmasset Llc Nucleoside phosphoramidates
JP5690286B2 (ja) 2009-03-04 2015-03-25 イデニク プハルマセウティカルス,インコーポレイテッド ホスホチオフェン及びホスホチアゾールhcvポリメラーゼ阻害剤
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
TWI583692B (zh) 2009-05-20 2017-05-21 基利法瑪席特有限責任公司 核苷磷醯胺
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
JP2013501068A (ja) 2009-08-05 2013-01-10 アイディニックス ファーマシューティカルズ インコーポレイテッド 大環状セリンプロテアーゼ阻害剤
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
JP5651834B2 (ja) * 2009-12-14 2015-01-14 豊勝 堀川 赤血球凝集阻害剤、および赤血球の凝集阻害方法
AR079528A1 (es) 2009-12-18 2012-02-01 Idenix Pharmaceuticals Inc Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
ES2660229T3 (es) * 2009-12-30 2018-03-21 Bagi Research Limited Materiales y métodos para la prevención y el tratamiento de infecciones virales
PL3290428T3 (pl) 2010-03-31 2022-02-07 Gilead Pharmasset Llc Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
KR101715981B1 (ko) 2010-03-31 2017-03-13 길리애드 파마셋 엘엘씨 뉴클레오사이드 포스포르아미데이트
MX2012011222A (es) 2010-04-01 2013-01-18 Centre Nat Rech Scient Compuestos y composiciones farmaceuticas para el tratamiento de infecciones virales.
BR112013008510A2 (pt) 2010-10-08 2016-07-05 Novartis Ag vitamina e formulações de inibidores de sulfamida ns3
US8841275B2 (en) 2010-11-30 2014-09-23 Gilead Pharmasset Llc 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
KR20120080674A (ko) * 2011-01-08 2012-07-18 주식회사한국전통의학연구소 대계근 추출물을 포함하는 백혈병 치료용 조성물 및 건강 기능성 식품
US8618125B2 (en) 2011-01-14 2013-12-31 Heptiva LLC Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance
AR085352A1 (es) 2011-02-10 2013-09-25 Idenix Pharmaceuticals Inc Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
JP2014514295A (ja) 2011-03-31 2014-06-19 アイディニックス ファーマシューティカルズ インコーポレイテッド ウイルス感染の治療のための化合物および薬学的組成物
WO2012143017A1 (en) 2011-04-17 2012-10-26 El-Sawy Mohamed Fakhr El-Din The use of orobancheace extract for the treatment of hepatitis c virus and nonalcoholic fatty liver disease
EP2755983B1 (en) 2011-09-12 2017-03-15 Idenix Pharmaceuticals LLC. Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
CN103906759A (zh) 2011-09-12 2014-07-02 埃迪尼克斯医药公司 用于治疗病毒感染的化合物和药物组合物
TW201331221A (zh) 2011-10-14 2013-08-01 Idenix Pharmaceuticals Inc 嘌呤核苷酸化合物類之經取代的3’,5’-環磷酸酯及用於治療病毒感染之醫藥組成物
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
AU2012345732B2 (en) 2011-11-30 2016-07-14 Emory University Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
US8809354B2 (en) 2011-12-31 2014-08-19 Sheikh Riazuddin 3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
US20130217644A1 (en) 2012-02-13 2013-08-22 Idenix Pharmaceuticals, Inc. Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate]
TWI498118B (zh) * 2012-04-27 2015-09-01 Ind Tech Res Inst 促進傷口癒合及血管新生的醫藥組合物與接骨木屬(蒴藋屬)(Sambucus)植物及菘藍屬(Isatis)植物之萃取物用於製備促進傷口癒合及血管新生之藥物的用途
US9109001B2 (en) 2012-05-22 2015-08-18 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphoramidate prodrugs for HCV infection
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
EA031301B1 (ru) 2012-05-22 2018-12-28 Иденикс Фармасьютикалз Ллс D-аминокислотные химические соединения для лечения заболеваний печени
MX353422B (es) 2012-10-08 2018-01-12 Idenix Pharmaceuticals Llc Análogos de 2'-cloronucleósido para infección por vhc.
WO2014063019A1 (en) 2012-10-19 2014-04-24 Idenix Pharmaceuticals, Inc. Dinucleotide compounds for hcv infection
EP2909222B1 (en) 2012-10-22 2021-05-26 Idenix Pharmaceuticals LLC 2',4'-bridged nucleosides for hcv infection
WO2014078436A1 (en) 2012-11-14 2014-05-22 Idenix Pharmaceuticals, Inc. D-alanine ester of sp-nucleoside analog
US20140140951A1 (en) 2012-11-14 2014-05-22 Idenix Pharmaceuticals, Inc. D-Alanine Ester of Rp-Nucleoside Analog
EP2935304A1 (en) 2012-12-19 2015-10-28 IDENIX Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
US9309275B2 (en) 2013-03-04 2016-04-12 Idenix Pharmaceuticals Llc 3′-deoxy nucleosides for the treatment of HCV
US9339541B2 (en) 2013-03-04 2016-05-17 Merck Sharp & Dohme Corp. Thiophosphate nucleosides for the treatment of HCV
US9187515B2 (en) 2013-04-01 2015-11-17 Idenix Pharmaceuticals Llc 2′,4′-fluoro nucleosides for the treatment of HCV
WO2014197578A1 (en) 2013-06-05 2014-12-11 Idenix Pharmaceuticals, Inc. 1',4'-thio nucleosides for the treatment of hcv
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
ES2900570T3 (es) 2013-08-27 2022-03-17 Gilead Pharmasset Llc Formulación de combinación de dos compuestos antivirales
WO2015042375A1 (en) 2013-09-20 2015-03-26 Idenix Pharmaceuticals, Inc. Hepatitis c virus inhibitors
WO2015061683A1 (en) 2013-10-25 2015-04-30 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
US20160271162A1 (en) 2013-11-01 2016-09-22 Idenix Pharmacueticals, Llc D-alanine phosphoramide pronucleotides of 2'-methyl 2'-fluro guanosine nucleoside compounds for the treatment of hcv
US20170198005A1 (en) 2013-11-27 2017-07-13 Idenix Pharmaceuticals Llc 2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
BR112016013745B1 (pt) 2013-12-16 2022-06-21 3M Innovative Properties Company Método para o controle de umidade, sistema de controle de umidade para manipular o ambiente gasoso no interior de uma câmara e esterilizador para esterilizar objetos com gás biocida
WO2015095419A1 (en) 2013-12-18 2015-06-25 Idenix Pharmaceuticals, Inc. 4'-or nucleosides for the treatment of hcv
US20170135990A1 (en) 2014-03-05 2017-05-18 Idenix Pharmaceuticals Llc Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
US20170066779A1 (en) 2014-03-05 2017-03-09 Idenix Pharmaceuticals Llc Solid forms of a flaviviridae virus inhibitor compound and salts thereof
US10202411B2 (en) 2014-04-16 2019-02-12 Idenix Pharmaceuticals Llc 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
US9789153B2 (en) 2014-07-02 2017-10-17 Hsiu-Hsien Tsai Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs
CN109917034A (zh) * 2019-03-19 2019-06-21 遵义医科大学 一种白及悬浮培养细胞中2,7-二羟基-4-甲氧基-9,10-二氢菲的定量检测方法
CN110179951A (zh) * 2019-06-28 2019-08-30 宗吉红 一种调治病毒性肝炎的中药组合物及其制备方法
KR102321162B1 (ko) * 2019-11-25 2021-11-02 강원대학교 산학협력단 황백 추출물을 유효성분으로 포함하는 산화아연 저감 사료용 보조제 조성물
KR102607247B1 (ko) * 2021-03-25 2023-11-29 한국식품연구원 도깨비고비 추출물을 유효성분으로 포함하는 항암 조성물
US20210361733A1 (en) * 2021-08-06 2021-11-25 Atta-ur- Rahman Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination
KR102389589B1 (ko) * 2021-09-29 2022-04-22 진지영 야관문 추출물을 포함하는 사료용 항진균성 조성물 및 그의 제조 방법
PL245314B1 (pl) * 2022-07-15 2024-06-24 Inst Chemii Fizycznej Polskiej Akademii Nauk Zastosowanie soli sodowej kwasu 5,5’-indygodisulfonowego do hamowania infekcji bakteriofagowych w procesach biotechnologicznych
CN117562962B (zh) * 2024-01-15 2024-03-12 四川育强本草生物技术有限公司 美洲大蠊或其提取物的用途及一种治疗猫口炎的中兽药组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808629A (en) * 1985-05-28 1989-02-28 Yaguang Liu Safe antileukemia drug, SAL
JPS6299318A (ja) * 1985-10-25 1987-05-08 Nonogawa Shoji:Kk 養毛剤
US4886666A (en) * 1987-01-27 1989-12-12 Yaguang Liu Pharmaceutical composition for inhibiting viruses and increasing immune function (PII)
US4985248A (en) * 1987-06-18 1991-01-15 Yaguang Liu Pharmaceutical composition containing a safe extracts of fruits and vegetables for the treating and preventing of diabetes
JP2974370B2 (ja) * 1990-05-11 1999-11-10 社団法人北里研究所 シアリダーゼ阻害剤
JPH0426650A (ja) * 1990-05-17 1992-01-29 Kuraray Co Ltd オレアノール酸の製造法
US5178865A (en) * 1990-06-19 1993-01-12 Cedars-Sinai Medical Center Chinese herbal extracts in the treatment of hiv related disease in vitro
US5366725A (en) * 1990-06-27 1994-11-22 Shinya Okubo Method for the treatment of cancer
CN1077379A (zh) * 1992-04-16 1993-10-20 张笑平 乙肝表面抗原转阴冲剂及其制备方法
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
CN1049338C (zh) * 1993-03-20 2000-02-16 赵三立 治疗乙型肝炎的药液
JP3183754B2 (ja) * 1993-07-20 2001-07-09 ポーラ化成工業株式会社 動脈硬化抑制剤及びこれを含有する組成物
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections

Also Published As

Publication number Publication date
US5989556A (en) 1999-11-23
WO1998001144A1 (en) 1998-01-15
DE69738535D1 (de) 2008-04-10
AU3664297A (en) 1998-02-02
JP2001516337A (ja) 2001-09-25
US6214350B1 (en) 2001-04-10
ATE387208T1 (de) 2008-03-15
DE69738535T2 (de) 2009-02-19
CA2271622A1 (en) 1998-01-15
ES2303342T3 (es) 2008-08-01
KR100511514B1 (ko) 2005-08-31
EP0914139A2 (en) 1999-05-12
CA2271622C (en) 2002-12-17
US5837257A (en) 1998-11-17
AU742854B2 (en) 2002-01-17
KR20000023648A (ko) 2000-04-25
EP0914139B1 (en) 2008-02-27
NZ333707A (en) 2000-09-29

Similar Documents

Publication Publication Date Title
BR9710355A (pt) Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.
WO2003063771A3 (en) N4-acylcytosine nucleosides for treatment of viral iinfections
ATE264914T1 (de) Antivirale proteine, dafür kodierende dna, und deren verwendung
FI904445A0 (fi) Antivirala foereningar.
HUP0202502A2 (hu) Virális fertőzőképességet blokkoló peptidek és eljárások ezek alkalmazására
ATE412667T1 (de) Langwirkende fusionspeptidinhibitoren gegen hiv- infektion
ES2187530T3 (es) Peptidos para reducir respuestas de linfocito t ctitotoxicos al virus de la hepatitis b.
SG170825A1 (en) Phosponate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production
PT92949A (pt) Processo para a preparacao de composicoes farmaceuticas contendo derivados da cisteina para o tratamento de doencas associadas com infeccoes provocadas por virus da imunodeficiencia humano
BR9913333A (pt) Inibição e tratamento do vìrus da hepatite b e flavivìrus com helioxatina e seus análogos
GEP20084377B (en) Agent for inhibiting membrane virus reproduction, method for the production thereof, pharmaceutical composition and method for inhibiting viral infections
ATE152717T1 (de) Gegen viren wirksame naphtochinon-verbindungen, zusammensetzungen und deren verwendungen
MX9301922A (es) Composiciones para el tratamiento de infeccion y enfermedad ocasionadas por el virus de hepatitis b (hbv).
MX9700414A (es) Agentes antivirales de difluoroestatona.
MY157594A (en) Compositions of matter useful in the treatment of viral infections derived from plant extracts
WO1998001144A2 (en) Antiviral agents from plant extracts and use for treatment of viral infections
AP9600896A0 (en) Anti-HIV triple combination.
RU93058325A (ru) Применение производных 1,3-оксатиолана для получения лекарственных препаратов для лечения или профилактики вирусной инфекции гепатита в, применение производных 1,3 - оксатиолана для лечения инфекций гепатита в, способ лечения гепатита в
CA2401295A1 (en) Process for preparing an anti viral medicinal product from plant extracts
UA42693C2 (uk) Лікарський засіб для лікування інфекції лентивірусом, препарат для лікування людини, яка інфікована лентивірусом
FI943295A (fi) Piliostigma thonningii -uutteet, niiden käyttö ja niitä sisältävät formuloinnit
ES2128322T3 (es) Peptidos que bloquean las infecciones debidas al virus de la inmunodeficiencia humana y procedimientos de utilizacion de estos peptidos.
WO2002009677A3 (en) Method to treat infectious diseases and/or to enhance antimicrobial efficacy of drugs
BR0207931A (pt) Anticorpos naturais ativos contra vìrus hiv
TW217986B (en) Compositions for the treatment of infection and disease caused by HBV

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 25 E 32 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.

B15K Others concerning applications: alteration of classification

Ipc: A61K 36/00 (2006.01), A61K 36/28 (2006.0