BR9305435A - Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos - Google Patents

Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos

Info

Publication number
BR9305435A
BR9305435A BR9305435A BR9305435A BR9305435A BR 9305435 A BR9305435 A BR 9305435A BR 9305435 A BR9305435 A BR 9305435A BR 9305435 A BR9305435 A BR 9305435A BR 9305435 A BR9305435 A BR 9305435A
Authority
BR
Brazil
Prior art keywords
determining
peptides corresponding
immunologically important
important epitopes
preparing
Prior art date
Application number
BR9305435A
Other languages
English (en)
Inventor
Leys Robert De
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8211622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9305435(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of BR9305435A publication Critical patent/BR9305435A/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/18Togaviridae; Flaviviridae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/14011Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR9305435A 1992-03-06 1993-03-08 Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos BR9305435A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92400598 1992-03-06
PCT/EP1993/000517 WO1993018054A2 (en) 1992-03-06 1993-03-08 Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them

Publications (1)

Publication Number Publication Date
BR9305435A true BR9305435A (pt) 1994-12-27

Family

ID=8211622

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9305435A BR9305435A (pt) 1992-03-06 1993-03-08 Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos

Country Status (16)

Country Link
US (3) US5891640A (pt)
EP (2) EP0589004B2 (pt)
JP (2) JP3443809B2 (pt)
KR (3) KR20030096423A (pt)
AT (2) ATE364621T1 (pt)
AU (1) AU671623B2 (pt)
BR (1) BR9305435A (pt)
CA (1) CA2102301C (pt)
DE (2) DE69324751T3 (pt)
DK (2) DK0589004T4 (pt)
ES (2) ES2133392T5 (pt)
GR (1) GR3030595T3 (pt)
NZ (2) NZ249838A (pt)
PT (1) PT891982E (pt)
SG (1) SG77551A1 (pt)
WO (1) WO1993018054A2 (pt)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US7413537B2 (en) * 1989-09-01 2008-08-19 Dyax Corp. Directed evolution of disulfide-bonded micro-proteins
AU8740491A (en) * 1990-09-28 1992-04-28 Protein Engineering Corporation Proteinaceous anti-dental plaque agents
ES2138784T3 (es) * 1990-12-14 2000-01-16 Innogenetics Nv Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES2330052T3 (es) * 1991-03-01 2009-12-03 Dyax Corporation Proteina quimerica que comprende micro-proteinas que tienen dos o mas puentes disulfuro y relaizaciones de las mismas.
US5773211A (en) * 1991-07-10 1998-06-30 Abbott Laboratories Differentiation of HTLV-I and HTLV-II using synthetic peptides
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
JP2723360B2 (ja) * 1992-05-29 1998-03-09 ハワード・フローレイ・インスティテュート・オブ・エクスペリメンタル・フィジオロジー・アンド・メディスン オリゴヌクレオチド−ポリアミドコンジュゲート
IT1270941B (it) * 1993-05-12 1997-05-26 Sorin Biomedica Spa Peptidi di hcv e loro usi.
DE69433160T2 (de) 1993-05-12 2004-07-08 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Konserviertes Motiv der Hepatitis C Virus E2/NS1 Region
US5885771A (en) * 1993-10-29 1999-03-23 Srl, Inc. Antigenic peptide compound and immunoassay
DK0992580T3 (da) 1993-11-04 2005-07-11 Innogenetics Nv Epitoper på human T-celler, som er immundominante for hepatitis C-virus
AU1443695A (en) * 1993-12-20 1995-07-10 Abbott Laboratories Differentiation of htlv-i and htlv-ii using synthetic peptides
US5709995A (en) 1994-03-17 1998-01-20 The Scripps Research Institute Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses
GB9410044D0 (en) * 1994-05-19 1994-07-06 Int Murex Tech Corp Assay
US6303574B1 (en) 1994-07-22 2001-10-16 The University Of North Carolina At Chapel Hill Scr SH3 binding peptides and methods of isolating and using same
US6184205B1 (en) * 1994-07-22 2001-02-06 University Of North Carolina At Chapel Hill GRB2 SH3 binding peptides and methods of isolating and using same
CA2195648A1 (en) * 1994-07-25 1996-02-08 Christoph Seidel Metal chelate-labelled peptides
WO1996003423A1 (de) * 1994-07-25 1996-02-08 Boehringer Mannheim Gmbh Hapten-markierte peptide
JPH09503396A (ja) 1994-07-29 1997-04-08 インノジェネティクス・エヌ・ブイ 診断用及び治療用の精製c型肝炎ウイルスエンベロープ蛋白
JP3665371B2 (ja) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 C型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法
FR2731225B1 (fr) * 1995-03-03 2003-10-31 Pasteur Institut Peptides de glycoproteine transmembranaire d'enveloppe et de proteine de capside du retrovirus humain du type hiv-1 et peptides presentant avec eux une parente immunologique
EP1849869A3 (fr) * 1994-10-20 2011-05-18 Institut Pasteur Séquences nucléotidiques d'antigènes rétroviraux VIH-1 groupe (ou sous-groupe) 0
AU780017B2 (en) * 1994-10-20 2005-02-24 Institut Pasteur Nucleotide sequences of HIV-1 type (or subtype) O retrovirus antigens
DE19504302A1 (de) * 1995-02-09 1996-08-14 Boehringer Mannheim Gmbh Methode zur serologischen Typisierung mittels typspezifischer Antigene
DE19505262C2 (de) * 1995-02-16 1998-06-18 Behring Diagnostics Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
WO1996027012A1 (en) * 1995-03-02 1996-09-06 Akzo Nobel N.V. Specific hiv-1 group o antigens
US6309820B1 (en) 1995-04-07 2001-10-30 University Of North Carolina At Chapel Hill Polypeptides having a functional domain of interest and methods of identifying and using same
WO1996031625A1 (en) * 1995-04-07 1996-10-10 Cytogen Corporation Polypeptides having a functional domain of interest and methods of identifying and using same
WO1996034013A1 (fr) * 1995-04-28 1996-10-31 Srl, Inc. Compose peptidique antigenique et methode de dosage immunologique
US6110465A (en) * 1995-06-07 2000-08-29 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of hypervariable region 1 of the envelope 2 gene of isolates of hepatitis C virus and the use of reagents derived from these hypervariable sequences in diagnostic methods and vaccines
JPH0967395A (ja) * 1995-08-31 1997-03-11 S R L:Kk 抗原ペプチド化合物および免疫学的測定方法
DE19534988A1 (de) * 1995-09-21 1997-03-27 Forssmann Wolf Georg Verfahren zur Herstellung und Anwendung synthetischer, biotinylierter Peptide
JP2002171972A (ja) * 1996-10-14 2002-06-18 Chemo Sero Therapeut Res Inst 肝炎ウイルスエピトープ
US6270777B1 (en) * 1996-12-20 2001-08-07 University Technologies International Inc. Conserved metalloprotease epitopes
FR2765688B1 (fr) 1997-07-04 1999-09-10 Pasteur Institut Reactif de detection et de suivi des infections provoquees par le virus d'epstein-barr et ses applications
EP1028972B1 (en) 1997-11-06 2010-09-29 Innogenetics N.V. Multi-mer peptides derived from hepatitis c virus envelope proteins for diagnostic use and vaccination purposes
EP0947525A1 (en) 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
EP1115847A1 (en) 1998-09-25 2001-07-18 Children's Medical Center Corporation Short peptides which selectively modulate the activity of protein kinases
SE9903031D0 (sv) * 1999-08-27 1999-08-27 Eurodiagnostica Ab Peptide mixture and vaccine against a chronic viral infection
IT1310160B1 (it) * 1999-09-03 2002-02-11 Invicta S P A Zaino con schienale provvisto di lamina elastica
JP2003064096A (ja) * 2001-08-29 2003-03-05 Mitsubishi Kagaku Bio-Clinical Laboratories Inc C型肝炎ウイルス特異的細胞障害性t細胞認識エピトープ
EP1436627A2 (en) * 2001-10-05 2004-07-14 Novozymes A/S Kit for predicting binding of a specific antibody to a potential immunogen and method of screening
CN100479859C (zh) * 2002-03-20 2009-04-22 厦门大学 一种针对靶的空间变构现象筛选可抑制和/或激活所述靶生物活性的物质的方法
CA2525640C (en) * 2003-04-11 2014-10-07 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Multiple antigenic peptide assay for detection of hiv or siv type retroviruses
US7604804B2 (en) 2004-02-09 2009-10-20 University Of Maryland Biotechnology Institute Enhancing anti-HIV efficiency through multivalent inhibitors targeting oligomeric gp120
US20070073039A1 (en) * 2005-09-29 2007-03-29 Chisari Francis V Peptides that inhibit viral infections
US8865398B2 (en) * 2006-09-01 2014-10-21 Abbott Laboratories Combination hepatitis C virus antigen and antibody detection method
EP2196804A4 (en) * 2007-10-05 2010-09-15 Kaneka Corp MARKED PEPTIDE WITH IMMOBILOBULIN BINDING ACTIVITY AND / OR AN IMMUNE LOBULIN COMPLEX AND METHOD FOR DETECTING OR REVIEWING IMMUNE LOBULIN WITH THE AID OF PEPTIDE
JP5707326B2 (ja) * 2008-09-02 2015-04-30 アンティジェン・エクスプレス・インコーポレーテッドAntigen Express,Inc. ヒトパピローマウイルス/Ii−keyのハイブリッドおよびその使用方法
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
MX365465B (es) 2013-03-21 2019-06-04 Sanofi Aventis Deutschland Sintesis de productos peptidicos que contienen imida ciclica.
SG11201506804VA (en) 2013-03-21 2015-09-29 Sanofi Aventis Deutschland Synthesis of hydantoin containing peptide products
EP2989120A4 (en) 2013-04-25 2017-04-19 Carmel-Haifa University Economic Corp. Synthetic anti-inflammatory peptides and use thereof
JP6312225B2 (ja) * 2013-12-27 2018-04-18 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft タンパク質に対するペプチドバインダーの系統的探索、成熟化、および伸長
CN108474795B (zh) 2015-04-20 2021-10-29 豪夫迈·罗氏有限公司 经由系统发现、成熟和延伸过程鉴定的针对蛋白质的特异性肽结合剂

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984003506A1 (en) * 1983-03-08 1984-09-13 Commw Serum Lab Commission Antigenically active amino acid sequences
US5075211A (en) * 1986-03-26 1991-12-24 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
US4833071A (en) * 1987-01-09 1989-05-23 United Biomedical, Inc. Peptide composition as anitgen for detection of antibodies to HTLV-I, as a vaccine for ATL and methods therefor
AP56A (en) * 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
IL88963A (en) * 1988-01-27 1996-05-14 Iaf Biochem Int Circular synthetic peptides and their mixtures for the detection of VIH antibodies and for the formation of vaccines
ATE120234T1 (de) 1988-06-09 1995-04-15 Innogenetics Nv Hiv-3-retrovirus und seine verwendung.
DE3901857A1 (de) * 1989-01-23 1990-07-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von hiv 2 antikoerpern
SU1612264A1 (ru) * 1989-03-01 1990-12-07 Институт биоорганической химии им.М.М.Шемякина Способ твердофазного иммуноферментного определени антител к вирусу иммунодефицита человека и меченный биотином синтетический пептид дл его осуществлени
HUT54896A (en) * 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
EP0438332B1 (fr) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptides dérivant de la glycoprotéine d'enveloppe de virus HIV, leurs applications à la détection d'une infection due à ces virus et à la vaccination contre le SIDA
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
EP0448095A1 (en) * 1990-03-21 1991-09-25 Wolf, Hans Joachim, Prof. Dr. Subregion of the retroviral ENV protein, DNA sequences encoding it and compositions for the diagnosis, prevention or therapy of retrovirus infections
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
ES2138784T3 (es) * 1990-12-14 2000-01-16 Innogenetics Nv Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
WO1992022571A1 (en) * 1991-06-13 1992-12-23 Baxter Diagnostics Inc. Immunoassay for non-a non-b hepatitis
CA2107732C (en) 1992-10-06 2003-04-08 Lutz G. Gurtler Retrovirus from the hiv group and its use

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CA2102301A1 (en) 1993-09-07
DE69324751T3 (de) 2005-03-17
KR20030096423A (ko) 2003-12-31
AU671623B2 (en) 1996-09-05
DE69324751D1 (de) 1999-06-10
WO1993018054A3 (en) 1994-02-17
SG77551A1 (en) 2005-04-28
EP0589004A1 (en) 1994-03-30
ATE364621T1 (de) 2007-07-15
DE69334148T2 (de) 2008-02-21
NZ299048A (en) 1998-09-24
EP0589004B1 (en) 1999-05-06
DE69324751T2 (de) 2000-01-13
KR100259223B1 (en) 2000-06-15
CA2102301C (en) 2008-09-16
ES2287969T3 (es) 2007-12-16
JP2004002379A (ja) 2004-01-08
JPH06505806A (ja) 1994-06-30
DK0589004T3 (da) 1999-11-15
AU3746393A (en) 1993-10-05
DK0891982T3 (da) 2007-09-03
US6165730A (en) 2000-12-26
DK0589004T4 (da) 2004-08-16
PT891982E (pt) 2007-07-27
EP0891982A3 (en) 2000-04-12
EP0891982B1 (en) 2007-06-13
ES2133392T5 (es) 2004-12-16
GR3030595T3 (en) 1999-10-29
EP0891982A2 (en) 1999-01-20
US6210903B1 (en) 2001-04-03
DE69334148D1 (de) 2007-07-26
ATE179716T1 (de) 1999-05-15
ES2133392T3 (es) 1999-09-16
WO1993018054A2 (en) 1993-09-16
NZ249838A (en) 1996-10-28
KR100257941B1 (ko) 2000-06-01
EP0589004B2 (en) 2004-05-06
US5891640A (en) 1999-04-06
JP3443809B2 (ja) 2003-09-08

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