BR122019017036B8 - compostos de arilamidas substituídas por tetrazol, usos dos referidos compostos e composição farmacêutica - Google Patents

compostos de arilamidas substituídas por tetrazol, usos dos referidos compostos e composição farmacêutica

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Publication number
BR122019017036B8
BR122019017036B8 BR122019017036A BR122019017036A BR122019017036B8 BR 122019017036 B8 BR122019017036 B8 BR 122019017036B8 BR 122019017036 A BR122019017036 A BR 122019017036A BR 122019017036 A BR122019017036 A BR 122019017036A BR 122019017036 B8 BR122019017036 B8 BR 122019017036B8
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BR
Brazil
Prior art keywords
compounds
tetrazole
pharmaceutical composition
optionally substituted
substituted arylamide
Prior art date
Application number
BR122019017036A
Other languages
English (en)
Portuguese (pt)
Other versions
BR122019017036B1 (pt
Inventor
Chen Li
Feng Lichun
Patrick Dillon Michael
Yang Minmin
Charles Hawley Ronald
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR122019017036B1 publication Critical patent/BR122019017036B1/pt
Publication of BR122019017036B8 publication Critical patent/BR122019017036B8/pt

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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BR122019017036A 2006-06-29 2007-06-18 compostos de arilamidas substituídas por tetrazol, usos dos referidos compostos e composição farmacêutica BR122019017036B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81729806P 2006-06-29 2006-06-29
PCT/EP2007/055997 WO2008000645A1 (en) 2006-06-29 2007-06-18 Tetrazole-substituted arylamides
BRPI0714315A BRPI0714315B8 (pt) 2006-06-29 2007-06-18 arilamidas substituídas com tetrazol, seu uso e composição farmacêutica que as compreende

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JP5021734B2 (ja) 2012-09-12
AR061667A1 (es) 2008-09-10
CN103159692B (zh) 2015-03-18
AU2007263809B2 (en) 2013-07-18
US20120214789A1 (en) 2012-08-23
TWI334414B (en) 2010-12-11
US9593128B2 (en) 2017-03-14
BR122019017036B1 (pt) 2020-06-09
IL195786A (en) 2015-02-26
US7595405B2 (en) 2009-09-29
EP2038264A1 (en) 2009-03-25
BRPI0714315A2 (pt) 2013-05-28
US10201525B2 (en) 2019-02-12
CN103159692A (zh) 2013-06-19
BRPI0714315B1 (pt) 2020-03-24
KR101103143B1 (ko) 2012-01-04
CL2007001887A1 (es) 2008-02-08
US8846945B2 (en) 2014-09-30
MX2008016423A (es) 2009-01-22
EP2592070A3 (en) 2013-05-22
CA2654915A1 (en) 2008-01-03
ES2596706T3 (es) 2017-01-11
US20080004442A1 (en) 2008-01-03
WO2008000645A1 (en) 2008-01-03
JP2012197303A (ja) 2012-10-18
JP5456846B2 (ja) 2014-04-02
US20090326220A1 (en) 2009-12-31
KR20090014221A (ko) 2009-02-06
US20170143672A1 (en) 2017-05-25
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CA2654915C (en) 2015-07-28
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CN101479250B (zh) 2013-05-22
CN101479250A (zh) 2009-07-08
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IL236492A0 (en) 2015-02-26
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