BR112019019706A2 - conjugado de anticorpo, anticorpo, composição farmacêutica, métodos para reduzir ou inibir angiogênese e para tratar um distúrbio ocular - Google Patents
conjugado de anticorpo, anticorpo, composição farmacêutica, métodos para reduzir ou inibir angiogênese e para tratar um distúrbio ocular Download PDFInfo
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Classifications
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762475163P | 2017-03-22 | 2017-03-22 | |
| PCT/US2018/023812 WO2018175752A1 (en) | 2017-03-22 | 2018-03-22 | Optimized antibody compositions for treatment of ocular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019019706A2 true BR112019019706A2 (pt) | 2020-04-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019019706A BR112019019706A2 (pt) | 2017-03-22 | 2018-03-22 | conjugado de anticorpo, anticorpo, composição farmacêutica, métodos para reduzir ou inibir angiogênese e para tratar um distúrbio ocular |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US11111291B2 (OSRAM) |
| EP (1) | EP3600442A1 (OSRAM) |
| JP (2) | JP7227151B2 (OSRAM) |
| KR (1) | KR20190138636A (OSRAM) |
| CN (1) | CN110612124B (OSRAM) |
| AR (1) | AR111249A1 (OSRAM) |
| AU (1) | AU2018237359B2 (OSRAM) |
| BR (1) | BR112019019706A2 (OSRAM) |
| CA (1) | CA3056248A1 (OSRAM) |
| CL (1) | CL2019002658A1 (OSRAM) |
| CO (1) | CO2019011582A2 (OSRAM) |
| CR (1) | CR20190481A (OSRAM) |
| IL (1) | IL269378A (OSRAM) |
| MA (1) | MA49279A (OSRAM) |
| MX (1) | MX2019011141A (OSRAM) |
| MY (1) | MY201701A (OSRAM) |
| PE (1) | PE20191758A1 (OSRAM) |
| PH (1) | PH12019502149A1 (OSRAM) |
| SG (1) | SG11201908650PA (OSRAM) |
| TW (1) | TWI839327B (OSRAM) |
| UA (1) | UA129242C2 (OSRAM) |
| WO (1) | WO2018175752A1 (OSRAM) |
Families Citing this family (26)
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| CL2019002658A1 (es) | 2019-12-27 |
| MY201701A (en) | 2024-03-13 |
| AU2018237359A1 (en) | 2019-10-10 |
| US20200002411A1 (en) | 2020-01-02 |
| US11891437B2 (en) | 2024-02-06 |
| MA49279A (fr) | 2020-02-05 |
| WO2018175752A1 (en) | 2018-09-27 |
| US11111291B2 (en) | 2021-09-07 |
| JP2020514376A (ja) | 2020-05-21 |
| US20210363231A1 (en) | 2021-11-25 |
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| AU2018237359B2 (en) | 2024-06-27 |
| CO2019011582A2 (es) | 2019-10-31 |
| RU2019132064A (ru) | 2021-04-22 |
| AR111249A1 (es) | 2019-06-19 |
| UA129242C2 (uk) | 2025-02-26 |
| CA3056248A1 (en) | 2018-09-27 |
| JP2023065424A (ja) | 2023-05-12 |
| CN110612124B (zh) | 2024-04-16 |
| IL269378A (en) | 2019-11-28 |
| MX2019011141A (es) | 2019-11-05 |
| PH12019502149A1 (en) | 2020-06-29 |
| RU2019132064A3 (OSRAM) | 2021-07-26 |
| KR20190138636A (ko) | 2019-12-13 |
| SG11201908650PA (en) | 2019-10-30 |
| TW201838649A (zh) | 2018-11-01 |
| JP7227151B2 (ja) | 2023-02-21 |
| EP3600442A1 (en) | 2020-02-05 |
| TWI839327B (zh) | 2024-04-21 |
| CN110612124A (zh) | 2019-12-24 |
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