BR112018010683A2 - ?composição, método para produzir uma composição, método que compreende administrar por via enteral uma substância e método para produzir um produto? - Google Patents
?composição, método para produzir uma composição, método que compreende administrar por via enteral uma substância e método para produzir um produto?Info
- Publication number
- BR112018010683A2 BR112018010683A2 BR112018010683A BR112018010683A BR112018010683A2 BR 112018010683 A2 BR112018010683 A2 BR 112018010683A2 BR 112018010683 A BR112018010683 A BR 112018010683A BR 112018010683 A BR112018010683 A BR 112018010683A BR 112018010683 A2 BR112018010683 A2 BR 112018010683A2
- Authority
- BR
- Brazil
- Prior art keywords
- producing
- composition
- substance
- product
- enterally administering
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 2
- 239000000126 substance Substances 0.000 title 1
- 229920001503 Glucan Polymers 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4725—Proteoglycans, e.g. aggreccan
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01005—Dextransucrase (2.4.1.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
Abstract
são divulgadas no presente pedido proteínas capazes de formar glucanos que têm ligações/ramificações alfa-1,2, reações e métodos para produzir este glucano, composições que compreendem este glucano, e várias aplicações dos mesmos.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2015095687 | 2015-11-26 | ||
CNPCT/CN2015/095687 | 2015-11-26 | ||
CN2016085547 | 2016-06-13 | ||
CNPCT/CN2016/085547 | 2016-06-13 | ||
PCT/US2016/063233 WO2017091533A1 (en) | 2015-11-26 | 2016-11-22 | Polypeptides capable of producing glucans having alpha-1,2 branches and use of the same |
Publications (4)
Publication Number | Publication Date |
---|---|
BR112018010683A2 true BR112018010683A2 (pt) | 2018-11-13 |
BR112018010683A8 BR112018010683A8 (pt) | 2019-02-26 |
BR112018010683B1 BR112018010683B1 (pt) | 2022-08-02 |
BR112018010683B8 BR112018010683B8 (pt) | 2022-08-23 |
Family
ID=57610383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018010683A BR112018010683B8 (pt) | 2015-11-26 | 2016-11-22 | Método para produzir uma composição de glucano |
Country Status (9)
Country | Link |
---|---|
US (2) | US10822383B2 (pt) |
EP (1) | EP3379945A1 (pt) |
JP (1) | JP7064435B2 (pt) |
CN (1) | CN108289494B (pt) |
AU (1) | AU2016359483B2 (pt) |
BR (1) | BR112018010683B8 (pt) |
CA (1) | CA3002666A1 (pt) |
MX (1) | MX2018006273A (pt) |
WO (1) | WO2017091533A1 (pt) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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KR102408803B1 (ko) | 2016-06-13 | 2022-06-13 | 뉴트리션 앤드 바이오사이언시스 유에스에이 4, 인크. | 세제 조성물 |
EP3469005B1 (en) | 2016-06-13 | 2020-06-03 | DuPont Industrial Biosciences USA, LLC | Detergent compositions |
KR102617012B1 (ko) | 2016-12-16 | 2023-12-26 | 뉴트리션 앤드 바이오사이언시스 유에스에이 4, 인크. | 친양쪽성 다당류 유도체 및 이를 포함하는 조성물 |
CN111936570A (zh) | 2017-12-14 | 2020-11-13 | 杜邦工业生物科学美国有限责任公司 | α-1,3-葡聚糖接枝共聚物 |
AU2019225994A1 (en) | 2018-02-23 | 2020-08-13 | Danisco Us Inc | Synthesis of glucan comprising alpha-1,3 glycosidic linkages with phosphorylase enzymes |
AU2019230061A1 (en) | 2018-03-09 | 2020-09-24 | Nutrition & Biosciences USA 4, Inc. | Engineered glucosyltransferases |
WO2019246171A1 (en) | 2018-06-20 | 2019-12-26 | The Procter & Gamble Company | A product comprising polysaccharide derivatives |
CN113286827A (zh) | 2018-06-20 | 2021-08-20 | 营养与生物科学美国第四公司 | 多糖衍生物和包含其的组合物 |
US20220267745A1 (en) | 2019-07-09 | 2022-08-25 | Nutrition & Biosciences USA 4, Inc. | Engineered alpha-1,3 branching enzymes |
AU2021263904A1 (en) * | 2020-04-29 | 2022-12-01 | Integrity Bio-Chemicals, Llc | Fatty acid reaction products of dextrins or dextran formulated with a surfactant |
CN116134054A (zh) | 2020-06-04 | 2023-05-16 | 营养与生物科学美国4公司 | 右旋糖酐-α-葡聚糖接枝共聚物及其衍生物 |
EP3922703A1 (en) | 2020-06-10 | 2021-12-15 | The Procter & Gamble Company | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
WO2021252558A1 (en) | 2020-06-10 | 2021-12-16 | The Procter & Gamble Company | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
EP4165090A1 (en) | 2020-06-10 | 2023-04-19 | Nutrition & Biosciences USA 4, Inc. | Poly alpha-1,6-glucan derivatives and compositions comprising same |
WO2021252575A1 (en) | 2020-06-10 | 2021-12-16 | Nutrition & Biosciences USA 4, Inc. | Poly alpha-1,6-glucan esters and compositions comprising same |
MX2022014567A (es) | 2020-06-10 | 2022-12-15 | Procter & Gamble | Composiciones para el cuidado de la ropa o cuidado de la vajilla que comprenden esteres de poli alfa-1,6-glucano. |
EP4165156A1 (en) | 2020-06-10 | 2023-04-19 | The Procter & Gamble Company | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
EP3922704A1 (en) | 2020-06-10 | 2021-12-15 | The Procter & Gamble Company | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
JP2023508432A (ja) | 2020-06-18 | 2023-03-02 | ザ プロクター アンド ギャンブル カンパニー | ポリビニルアルコールフィルムと、カチオン性ポリα-1,6-グルカンエーテル化合物とを含む水溶性単位用量物品 |
EP3926029A1 (en) | 2020-06-18 | 2021-12-22 | The Procter & Gamble Company | Treatment compositions comprising cationic poly alpha-1,6-glucan ethers |
CN116194489A (zh) | 2020-06-18 | 2023-05-30 | 营养与生物科学美国4公司 | 阳离子聚α-1,6-葡聚糖醚和包含其的组合物 |
EP4176072A1 (fr) * | 2020-07-02 | 2023-05-10 | Institut National des Sciences Appliquées de Toulouse | Procédé de preparation de polyglucosides d'alkyle et polyglucosides d'alkyle obtenus selon le procédé |
CN112553271A (zh) * | 2020-12-15 | 2021-03-26 | 江南大学 | 一种含α-1,2糖苷键低热量糊精的制备方法 |
US20240117275A1 (en) | 2021-01-29 | 2024-04-11 | Danisco Us Inc. | Compositions for cleaning and methods related thereto |
EP4294848A1 (en) | 2021-02-19 | 2023-12-27 | Nutrition & Biosciences USA 4, Inc. | Oxidized polysaccharide derivatives |
EP4334363A1 (en) | 2021-05-04 | 2024-03-13 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising insoluble alpha-glucan |
EP4334364A1 (en) | 2021-05-04 | 2024-03-13 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising oxidized insoluble alpha-glucan |
WO2023287684A1 (en) | 2021-07-13 | 2023-01-19 | Nutrition & Biosciences USA 4, Inc. | Cationic glucan ester derivatives |
EP4119647A1 (en) | 2021-07-16 | 2023-01-18 | The Procter & Gamble Company | Liquid hand dishwashing detergent composition |
WO2023055902A1 (en) | 2021-09-30 | 2023-04-06 | Dupont Nutrition Biosciences Aps | Method for reducing sugar in food stuff |
WO2023081341A1 (en) | 2021-11-05 | 2023-05-11 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising one cationic alpha- 1,6-glucan derivative and one alpha- 1,3-glucan |
WO2023114942A1 (en) | 2021-12-16 | 2023-06-22 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising cationic alpha-glucan ethers in aqueous polar organic solvents |
WO2023137258A1 (en) | 2022-01-12 | 2023-07-20 | Nutrition & Biosciences USA 4, Inc. | Coating compositions comprising rubber and insoluble alpha-glucan |
CN114230684A (zh) * | 2022-01-14 | 2022-03-25 | 长春永晨生物技术有限公司 | α-1,2葡聚糖的纯化方法、α-1,2葡聚糖及其应用 |
WO2023183280A1 (en) | 2022-03-21 | 2023-09-28 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising insoluble alpha-glucan |
WO2024015769A1 (en) | 2022-07-11 | 2024-01-18 | Nutrition & Biosciences USA 4, Inc. | Amphiphilic glucan ester derivatives |
WO2024081773A1 (en) | 2022-10-14 | 2024-04-18 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising water, cationic alpha-1,6-glucan ether and organic solvent |
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-
2016
- 2016-11-22 MX MX2018006273A patent/MX2018006273A/es unknown
- 2016-11-22 CN CN201680069006.1A patent/CN108289494B/zh active Active
- 2016-11-22 US US15/767,689 patent/US10822383B2/en active Active
- 2016-11-22 CA CA3002666A patent/CA3002666A1/en not_active Abandoned
- 2016-11-22 EP EP16816788.0A patent/EP3379945A1/en active Pending
- 2016-11-22 WO PCT/US2016/063233 patent/WO2017091533A1/en active Application Filing
- 2016-11-22 BR BR112018010683A patent/BR112018010683B8/pt active IP Right Grant
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- 2016-11-22 JP JP2018527120A patent/JP7064435B2/ja active Active
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JP2019505171A (ja) | 2019-02-28 |
BR112018010683A8 (pt) | 2019-02-26 |
AU2016359483B2 (en) | 2020-10-29 |
CN108289494B (zh) | 2022-06-14 |
US20180282385A1 (en) | 2018-10-04 |
US20210206819A1 (en) | 2021-07-08 |
US10822383B2 (en) | 2020-11-03 |
CN108289494A (zh) | 2018-07-17 |
CA3002666A1 (en) | 2017-06-01 |
EP3379945A1 (en) | 2018-10-03 |
BR112018010683B8 (pt) | 2022-08-23 |
MX2018006273A (es) | 2018-08-16 |
BR112018010683B1 (pt) | 2022-08-02 |
JP7064435B2 (ja) | 2022-05-10 |
WO2017091533A1 (en) | 2017-06-01 |
AU2016359483A1 (en) | 2018-05-10 |
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