BR112018008783A8 - terapia-alvo de câncer - Google Patents
terapia-alvo de câncerInfo
- Publication number
- BR112018008783A8 BR112018008783A8 BR112018008783A BR112018008783A BR112018008783A8 BR 112018008783 A8 BR112018008783 A8 BR 112018008783A8 BR 112018008783 A BR112018008783 A BR 112018008783A BR 112018008783 A BR112018008783 A BR 112018008783A BR 112018008783 A8 BR112018008783 A8 BR 112018008783A8
- Authority
- BR
- Brazil
- Prior art keywords
- cancer target
- target therapy
- antigen
- subject
- nucleic acid
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title 1
- 238000002626 targeted therapy Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000002601 intratumoral effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
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Abstract
algumas formas de realização da presente invenção são dirigidas para métodos que incluem a entrega a um sujeito de uma ácido nucleico que codifica um antigénio, em que o ácido nucleico é entregue através de um veículo de tumor-selectiva ou por injecção intratumoral, e administrar ao indivíduo uma célula imune que expressam um receptor que se liga ao antigénio.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562249013P | 2015-10-30 | 2015-10-30 | |
US62/249,013 | 2015-10-30 | ||
PCT/US2016/059452 WO2017075440A1 (en) | 2015-10-30 | 2016-10-28 | Targeted cancer therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018008783A2 BR112018008783A2 (pt) | 2018-10-30 |
BR112018008783A8 true BR112018008783A8 (pt) | 2019-02-26 |
Family
ID=58631180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018008783A BR112018008783A8 (pt) | 2015-10-30 | 2016-10-28 | terapia-alvo de câncer |
Country Status (11)
Country | Link |
---|---|
US (2) | US11207339B2 (pt) |
EP (1) | EP3368656A4 (pt) |
JP (1) | JP2018532801A (pt) |
KR (1) | KR20180095511A (pt) |
CN (1) | CN108473950A (pt) |
AU (1) | AU2016343722A1 (pt) |
BR (1) | BR112018008783A8 (pt) |
CA (1) | CA3003728A1 (pt) |
IL (1) | IL259017A (pt) |
MX (1) | MX2018005468A (pt) |
WO (1) | WO2017075440A1 (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010120266A1 (en) | 2009-04-13 | 2010-10-21 | Inserm, Institut National De La Sante Et De La Recherche Medicale | Hpv particles and uses thereof |
WO2013119877A1 (en) | 2012-02-07 | 2013-08-15 | Aura Biosciences, Inc. | Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells |
HUE043463T2 (hu) | 2013-09-18 | 2019-08-28 | Aura Biosciences Inc | Vírusszerû részecske konjugátumok tumorok kezelésére |
JP2018532801A (ja) | 2015-10-30 | 2018-11-08 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 標的化がん療法 |
CN107245500B (zh) * | 2017-05-27 | 2019-05-17 | 上海优卡迪生物医药科技有限公司 | 一种基于octs技术的淋系白血病car-t治疗载体及其构建方法和应用 |
JP2020524710A (ja) | 2017-06-23 | 2020-08-20 | パソヴァックス エルエルシー | 免疫応答の抗原特異的リダイレクターとしてのキメラウイルス様粒子およびその使用 |
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EP3368656A1 (en) | 2018-09-05 |
CN108473950A (zh) | 2018-08-31 |
JP2018532801A (ja) | 2018-11-08 |
BR112018008783A2 (pt) | 2018-10-30 |
IL259017A (en) | 2018-06-28 |
KR20180095511A (ko) | 2018-08-27 |
US20220313720A1 (en) | 2022-10-06 |
AU2016343722A1 (en) | 2018-05-24 |
MX2018005468A (es) | 2018-11-09 |
CA3003728A1 (en) | 2017-05-04 |
US20180311269A1 (en) | 2018-11-01 |
US11207339B2 (en) | 2021-12-28 |
WO2017075440A1 (en) | 2017-05-04 |
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