BR112015023886A2 - polipeptídeo, ácido nucleico, composição farmacêutica, e, método - Google Patents

polipeptídeo, ácido nucleico, composição farmacêutica, e, método

Info

Publication number
BR112015023886A2
BR112015023886A2 BR112015023886A BR112015023886A BR112015023886A2 BR 112015023886 A2 BR112015023886 A2 BR 112015023886A2 BR 112015023886 A BR112015023886 A BR 112015023886A BR 112015023886 A BR112015023886 A BR 112015023886A BR 112015023886 A2 BR112015023886 A2 BR 112015023886A2
Authority
BR
Brazil
Prior art keywords
polypeptide
nucleic acid
pharmaceutical composition
vaccine
describes
Prior art date
Application number
BR112015023886A
Other languages
English (en)
Other versions
BR112015023886B1 (pt
Inventor
Olsen Anja
Follmann Frank
Rosenkrands Ida
Lawætz Andersen Peter
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of BR112015023886A2 publication Critical patent/BR112015023886A2/pt
Publication of BR112015023886B1 publication Critical patent/BR112015023886B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/118—Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

resumo polipeptídeo, ácido nucleico, composição farmacêutica, e, método a presente invenção descreve uma vacina eficiente contra chlamydia trachomatis (ct). a vacina se baseia em moléculas de fusão recombinante que são capazes de gerar uma resposta de anticorpo neutralizante altamente titulada que é para proteção contra várias serovariedades de ct. a nossa invenção descreve também a combinação de fragmentos promovendo o anticorpo com antigénios de ct. que são alvos para as células t com o objetivo de prover uma vacina que ativa ambos os ramos do sistema imune. 1/1
BR112015023886-6A 2013-03-18 2014-03-17 Polipeptídeo e composição farmacêutica BR112015023886B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201300155 2013-03-18
DKPA201300155 2013-03-18
DKPA201300684 2013-12-11
DKPA201300684 2013-12-11
PCT/DK2014/000015 WO2014146663A1 (en) 2013-03-18 2014-03-17 Vaccines against chlamydia sp.

Publications (2)

Publication Number Publication Date
BR112015023886A2 true BR112015023886A2 (pt) 2017-10-24
BR112015023886B1 BR112015023886B1 (pt) 2023-05-16

Family

ID=50639248

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023886-6A BR112015023886B1 (pt) 2013-03-18 2014-03-17 Polipeptídeo e composição farmacêutica

Country Status (19)

Country Link
US (3) US20140275478A1 (pt)
EP (1) EP2976355B1 (pt)
JP (3) JP2016514713A (pt)
CN (2) CN105377879B (pt)
AU (1) AU2014234765B2 (pt)
BR (1) BR112015023886B1 (pt)
CA (1) CA2907199C (pt)
CY (1) CY1122905T1 (pt)
DK (1) DK2976355T3 (pt)
ES (1) ES2781579T3 (pt)
HR (1) HRP20200511T1 (pt)
HU (1) HUE048573T2 (pt)
LT (1) LT2976355T (pt)
PL (1) PL2976355T3 (pt)
PT (1) PT2976355T (pt)
RS (1) RS60135B1 (pt)
RU (1) RU2723046C2 (pt)
SI (1) SI2976355T1 (pt)
WO (1) WO2014146663A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2900757T3 (es) 2015-02-10 2022-03-18 Ohio State Innovation Foundation Plataformas de células B activadas por clamidia y procedimientos de las mismas
CN104800841B (zh) * 2015-03-02 2019-04-02 中国农业科学院兰州兽医研究所 牦牛流产衣原体灭活疫苗及其制备方法
CA2980227A1 (en) 2015-03-24 2016-09-29 Universiteit Gent A method for the detection of chlamydia suis
AU2016349937B2 (en) * 2015-11-04 2021-09-30 University Of The Sunshine Coast Chlamydia antigens and uses thereof
CA3004924A1 (en) 2015-11-10 2017-05-18 Ohio State Innovation Foundation Methods and compositions related to accelerated humoral affinity
NL2019320B1 (en) * 2017-03-02 2018-09-21 Biosparq B V Diagnostic method and system for diagnosis
CN110603053A (zh) * 2017-03-23 2019-12-20 俄亥俄州国家创新基金会 重组衣原体活化的b细胞平台及其使用方法
RU2721123C1 (ru) * 2019-09-26 2020-05-18 федеральное государственное бюджетное учреждение «Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения Российской Федерации Штамм рекомбинантной псевдоаденовирусной частицы, экспрессирующий химерный ген MBL-CT666 Chlamydia trachomatis, способ его получения, иммуногенная композиция для защиты от урогенитального хламидиоза человека
US20240131138A1 (en) * 2020-12-23 2024-04-25 Institut National De La Santé Et De La Recherche Médicale (Inserm) Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells
CN116854812B (zh) * 2022-03-23 2024-09-24 东莞市朋志生物科技有限公司 抗沙眼衣原体的抗体、检测沙眼衣原体的试剂和试剂盒
US20240299524A1 (en) * 2023-03-02 2024-09-12 Sanofi Compositions for use in treatment of chlamydia

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599231A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4599230A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4608251A (en) 1984-11-09 1986-08-26 Pitman-Moore, Inc. LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
US4601903A (en) 1985-05-01 1986-07-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
US5869608A (en) * 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
US5837268A (en) * 1991-10-16 1998-11-17 University Of Saskatchewan GnRH-leukotoxin chimeras
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
KR950702635A (ko) * 1992-07-31 1995-07-29 크리스틴 헬렌 수덴 감쇠 박테리아에서 재조합 융합 단백질의 발현(Expression of recombinant fusion proteins in attenuated bacteria)
AU669000B2 (en) 1992-09-18 1996-05-23 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Synthetic peptide vaccine for chlamydia trachomatis
GB9516293D0 (en) * 1995-08-09 1995-10-11 Immunova Ltee Novel peptides and their use as vaccines
JP2002512622A (ja) * 1997-05-06 2002-04-23 バンダービルト ユニバーシティー クラミジアにより引き起こされる感染の診断および管理のための抗クラミジア剤の組成物
JP2004522432A (ja) * 2000-12-22 2004-07-29 シノヴィス・リミテッド Ｔｏｌｌ関連レセプター（ｔｒｒ）シグナル伝達の調節方法
US7105171B2 (en) 2002-03-07 2006-09-12 The Regents Of The University Of California Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
MXPA05013260A (es) * 2003-06-26 2006-03-09 Chiron Corp Composiciones inmunogenicas para chlamydia trachomatis.
CA2585011C (en) * 2004-10-25 2014-02-18 Statens Serum Institut Chlamydia trachomatis antigens for vaccine and diagnostic use
CA2609038A1 (en) * 2005-05-18 2006-11-23 Trinity Biosystems, Inc. Methods and compositions for immunizing against chlamydia infection
TW201012929A (en) * 2008-09-29 2010-04-01 Univ Nat Pingtung Sci & Tech A hybridoma cell line producing monoclonal antibodies against chalmydophila aborts
EP2413959A4 (en) * 2009-01-29 2013-06-19 British Columbia Cancer Agency CHLAMYDIA-ANTIGENE COMPREHENSIVE COMPOSITIONS
ES2788728T3 (es) * 2010-05-28 2020-10-22 Spixia Biotechnology Ab Antígeno de la MOMP quimérica, método y uso
PL2729158T3 (pl) * 2011-06-17 2018-07-31 Universiteit Gent Szczepionki przeciwko Chlamydia

Also Published As

Publication number Publication date
CA2907199C (en) 2023-10-17
AU2014234765B2 (en) 2018-01-25
RU2015141214A (ru) 2017-04-26
WO2014146663A1 (en) 2014-09-25
JP7510142B2 (ja) 2024-07-03
JP7506930B2 (ja) 2024-06-27
CA2907199A1 (en) 2014-09-25
JP2021193123A (ja) 2021-12-23
US20140275478A1 (en) 2014-09-18
CN113185587A (zh) 2021-07-30
PT2976355T (pt) 2020-04-02
DK2976355T3 (en) 2020-03-30
CN105377879A (zh) 2016-03-02
SI2976355T1 (sl) 2020-07-31
EP2976355A1 (en) 2016-01-27
CN105377879B (zh) 2021-05-04
CY1122905T1 (el) 2021-10-29
JP2019163253A (ja) 2019-09-26
RU2723046C2 (ru) 2020-06-08
US20210205433A1 (en) 2021-07-08
HUE048573T2 (hu) 2020-08-28
AU2014234765A1 (en) 2015-10-08
HRP20200511T1 (hr) 2020-06-26
ES2781579T3 (es) 2020-09-03
EP2976355B1 (en) 2020-01-01
PL2976355T3 (pl) 2020-07-13
LT2976355T (lt) 2020-04-10
RS60135B1 (sr) 2020-05-29
US10925954B2 (en) 2021-02-23
BR112015023886B1 (pt) 2023-05-16
JP2016514713A (ja) 2016-05-23
US20190099478A1 (en) 2019-04-04

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/03/2014, OBSERVADAS AS CONDICOES LEGAIS