BR112017001860A2 - peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal - Google Patents

peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal

Info

Publication number
BR112017001860A2
BR112017001860A2 BR112017001860-8A BR112017001860A BR112017001860A2 BR 112017001860 A2 BR112017001860 A2 BR 112017001860A2 BR 112017001860 A BR112017001860 A BR 112017001860A BR 112017001860 A2 BR112017001860 A2 BR 112017001860A2
Authority
BR
Brazil
Prior art keywords
methods
pharmaceutical composition
monoclonal antibody
synthetic peptide
dosage regimen
Prior art date
Application number
BR112017001860-8A
Other languages
English (en)
Portuguese (pt)
Inventor
M. Anantharamaiah Gattadahalli
Goldberg Dennis
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of BR112017001860A2 publication Critical patent/BR112017001860A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112017001860-8A 2014-07-31 2015-07-20 peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal BR112017001860A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462031585P 2014-07-31 2014-07-31
US62/031585 2014-07-31
PCT/US2015/041162 WO2016018665A1 (en) 2014-07-31 2015-07-20 Apoe mimetic peptides and higher potency to clear plasma cholesterol

Publications (1)

Publication Number Publication Date
BR112017001860A2 true BR112017001860A2 (pt) 2018-02-27

Family

ID=55218188

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017001860-8A BR112017001860A2 (pt) 2014-07-31 2015-07-20 peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal

Country Status (10)

Country Link
US (2) USRE50320E1 (enExample)
EP (1) EP3189069B1 (enExample)
JP (2) JP7081923B2 (enExample)
CN (1) CN107074923B (enExample)
AU (1) AU2015298263B2 (enExample)
BR (1) BR112017001860A2 (enExample)
CA (1) CA2954475C (enExample)
IL (1) IL250302B (enExample)
MX (1) MX383117B (enExample)
WO (1) WO2016018665A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE50320E1 (en) 2014-07-31 2025-03-04 Uab Research Foundation APOE mimetic peptides and higher potency to clear plasma cholesterol

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015022624A2 (pt) * 2013-03-14 2017-10-31 Uab Research Foundation regime de dose, e, método para tratamento de aterosclerose
DK3362063T3 (da) 2015-10-14 2023-04-03 Massachusetts Eye & Ear Infirmary Højdosisstatiner til aldersrelateret makuladegeneration
WO2017120568A1 (en) * 2016-01-08 2017-07-13 Lipimetix Development, Inc. Apoe mimetic peptide compositions
CN110545836A (zh) * 2017-01-24 2019-12-06 马克雷根有限公司 用载脂蛋白模拟物治疗与年龄有关的黄斑变性和其他眼部疾病
WO2018190896A1 (en) 2017-04-13 2018-10-18 Lipimetix Development, Inc. Apoe mimetic peptide compositions
TW202010752A (zh) 2018-04-11 2020-03-16 美商立畢密蒂斯發展公司 擬脂蛋白元(apoe)之肽組合物
WO2020096020A1 (ja) 2018-11-08 2020-05-14 国立大学法人埼玉大学 リポソーム結合ペプチド、リポソーム結合ペプチドの作製用コンストラクト及びリポソーム
CN111617232B (zh) * 2020-06-04 2023-04-18 安域生物科技(杭州)有限公司 一类ApoE受体蛋白短肽阻断剂在阿尔茨海默病的应用
CN114940711B (zh) * 2021-10-25 2023-05-12 中山大学 载脂蛋白a-i模拟肽及其应用
WO2023215838A1 (en) * 2022-05-05 2023-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Short apolipoprotein e mimetic peptides and methods of use
WO2024238337A1 (en) * 2023-05-17 2024-11-21 The Medical College Of Wisconsin Dual-domain peptide for depleting hmgb1 from the circulation via liver hspg system
WO2025147594A1 (en) * 2024-01-04 2025-07-10 University Of Florida Research Foundation, Incorporated Peptides and method of use in preparing nanodiscs

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