BR112016015944A8 - processo para produzir comprimido, que usa radiofrequência e partículas revestidas dissipadoras de energia - Google Patents

processo para produzir comprimido, que usa radiofrequência e partículas revestidas dissipadoras de energia Download PDF

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Publication number
BR112016015944A8
BR112016015944A8 BR112016015944A BR112016015944A BR112016015944A8 BR 112016015944 A8 BR112016015944 A8 BR 112016015944A8 BR 112016015944 A BR112016015944 A BR 112016015944A BR 112016015944 A BR112016015944 A BR 112016015944A BR 112016015944 A8 BR112016015944 A8 BR 112016015944A8
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BR
Brazil
Prior art keywords
energy
coated particles
dissipating energy
powder mixture
produce tablet
Prior art date
Application number
BR112016015944A
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English (en)
Other versions
BR112016015944A2 (pt
Inventor
David B Cochran
Vipul Dave
Gregory Koll
Gerard P Mcnally
Christopher E Szymczak
Stephen Ulrich
Original Assignee
Johnson & Johnson Consumer Inc
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Publication date
Application filed by Johnson & Johnson Consumer Inc filed Critical Johnson & Johnson Consumer Inc
Publication of BR112016015944A2 publication Critical patent/BR112016015944A2/pt
Publication of BR112016015944A8 publication Critical patent/BR112016015944A8/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

em um aspecto, a presente invenção apresenta um processo para produzir um comprimido que compreende ao menos um agente farmaceuticamente ativo, sendo que o dito método compreende a etapa de aplicar energia de radiofrequência a um mistura em pó para sinterizar a dita mistura em pó no dito comprimido, sendo que a dita mistura em pó compreende partículas revestidas dissipadoras de energia e o dito ao menos um agente farmaceuticamente ativo, sendo que as ditas partículas revestidas dissipadoras de energia compreendem um substrato que é ao menos parcialmente coberto com um revestimento dissipador de energia que compreende ao menos um ativador, sendo que o dito substrato tem um valor q maior que 100 e o dito ativador tem um valor q menor que 75.
BR112016015944A 2014-01-10 2015-01-08 processo para produzir comprimido, que usa radiofrequência e partículas revestidas dissipadoras de energia BR112016015944A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461925713P 2014-01-10 2014-01-10
PCT/US2015/010647 WO2015105992A1 (en) 2014-01-10 2015-01-08 Process for making tablet using radiofrequency and lossy coated particles

Publications (2)

Publication Number Publication Date
BR112016015944A2 BR112016015944A2 (pt) 2017-08-08
BR112016015944A8 true BR112016015944A8 (pt) 2020-06-09

Family

ID=52432954

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016015944A BR112016015944A8 (pt) 2014-01-10 2015-01-08 processo para produzir comprimido, que usa radiofrequência e partículas revestidas dissipadoras de energia

Country Status (13)

Country Link
US (2) US9789066B2 (pt)
EP (1) EP3091966B1 (pt)
JP (1) JP6505721B2 (pt)
KR (1) KR20160107254A (pt)
CN (1) CN106068120B (pt)
AU (2) AU2015204763A1 (pt)
BR (1) BR112016015944A8 (pt)
CA (1) CA2936216C (pt)
ES (1) ES2750323T3 (pt)
IL (1) IL246648B (pt)
MX (1) MX368159B (pt)
RU (1) RU2712267C2 (pt)
WO (1) WO2015105992A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015108992A1 (en) 2014-01-15 2015-07-23 Blueprint Medicines Corporation Heterobicyclic compounds and their use as fgfr4 receptor inhibitors
EP3123843B1 (en) 2014-03-25 2021-06-09 Stratasys Ltd. Method for fabricating cross-layer pattern
CN107614265A (zh) * 2015-03-25 2018-01-19 斯特拉塔西斯公司 导电油墨原位烧结的方法和系统
WO2018021264A1 (ja) * 2016-07-28 2018-02-01 沢井製薬株式会社 口腔内崩壊性を有する被検物の食感評価方法及び食感評価装置
US20180147153A1 (en) * 2016-11-28 2018-05-31 Johnson & Johnson Consumer Inc. Process for making a coated dosage form
US10493026B2 (en) * 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
WO2024039897A2 (en) * 2022-08-19 2024-02-22 Mirati Therapeutics, Inc. Adagrasib solid pharmaceutical compositions

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US20150196493A1 (en) 2015-07-16
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US9789066B2 (en) 2017-10-17
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JP6505721B2 (ja) 2019-04-24
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CN106068120A (zh) 2016-11-02
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