BR112015023001B8 - Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd) - Google Patents

Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd)

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Publication number
BR112015023001B8
BR112015023001B8 BR112015023001A BR112015023001A BR112015023001B8 BR 112015023001 B8 BR112015023001 B8 BR 112015023001B8 BR 112015023001 A BR112015023001 A BR 112015023001A BR 112015023001 A BR112015023001 A BR 112015023001A BR 112015023001 B8 BR112015023001 B8 BR 112015023001B8
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Brazil
Prior art keywords
composition
treatment
muscular dystrophy
dmd
same
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BR112015023001A
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English (en)
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BR112015023001B1 (pt
BR112015023001A8 (pt
BR112015023001A2 (pt
Inventor
K Bestwick Richard
Elizabeth Frank Diane
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Sarepta Therapeutics Inc
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Application filed by Sarepta Therapeutics Inc filed Critical Sarepta Therapeutics Inc
Publication of BR112015023001A2 publication Critical patent/BR112015023001A2/pt
Publication of BR112015023001A8 publication Critical patent/BR112015023001A8/pt
Publication of BR112015023001B1 publication Critical patent/BR112015023001B1/pt
Publication of BR112015023001B8 publication Critical patent/BR112015023001B8/pt

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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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Abstract

COMPOSIÇÕES RESULTANTES DA RETIRADA DE EXONS PARA O TRATAMENTO DE DISTROFIA MUSCULAR. A presente invenção refere-se a moléculas antisense capazes de se ligarem a um sítio alvo selecionado no gene da distrofina humana para induzir a retirada (skipping) do exon 44.
BR112015023001A 2013-03-14 2014-03-14 Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd) BR112015023001B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784547P 2013-03-14 2013-03-14
US61/784.547 2013-03-14
PCT/US2014/029689 WO2014153220A2 (en) 2013-03-14 2014-03-14 Exon skipping compositions for treating muscular dystrophy

Publications (4)

Publication Number Publication Date
BR112015023001A2 BR112015023001A2 (pt) 2017-11-14
BR112015023001A8 BR112015023001A8 (pt) 2018-01-23
BR112015023001B1 BR112015023001B1 (pt) 2022-07-19
BR112015023001B8 true BR112015023001B8 (pt) 2022-08-09

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ID=50694004

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BR112015023001A BR112015023001B8 (pt) 2013-03-14 2014-03-14 Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd)
BR122020016865-0A BR122020016865B1 (pt) 2013-03-14 2014-03-14 Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd)

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BR122020016865-0A BR122020016865B1 (pt) 2013-03-14 2014-03-14 Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd)

Country Status (16)

Country Link
US (9) US9217148B2 (pt)
EP (3) EP3633035A1 (pt)
JP (5) JP6449231B2 (pt)
KR (6) KR102521608B1 (pt)
CN (3) CN117844807A (pt)
AU (3) AU2014236140B2 (pt)
BR (2) BR112015023001B8 (pt)
CA (1) CA2906209A1 (pt)
EA (2) EA035882B1 (pt)
ES (1) ES2762881T3 (pt)
HK (1) HK1219755A1 (pt)
IL (3) IL293975A (pt)
MX (2) MX366485B (pt)
NZ (4) NZ631245A (pt)
SA (1) SA515361125B1 (pt)
WO (1) WO2014153220A2 (pt)

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