BR112015012711A2 - método de produção de uma vacina de mycoplasma - Google Patents

método de produção de uma vacina de mycoplasma

Info

Publication number
BR112015012711A2
BR112015012711A2 BR112015012711A BR112015012711A BR112015012711A2 BR 112015012711 A2 BR112015012711 A2 BR 112015012711A2 BR 112015012711 A BR112015012711 A BR 112015012711A BR 112015012711 A BR112015012711 A BR 112015012711A BR 112015012711 A2 BR112015012711 A2 BR 112015012711A2
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BR
Brazil
Prior art keywords
mycoplasma
individual
immunogenic composition
production
relates
Prior art date
Application number
BR112015012711A
Other languages
English (en)
Other versions
BR112015012711B1 (pt
Inventor
V Iyer Arun
Neubauer Axel
Thomas Martinson Brian
Margaret Muehlenthaler Christine
M Murphy Jordan Dianna
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49917778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015012711(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of BR112015012711A2 publication Critical patent/BR112015012711A2/pt
Publication of BR112015012711B1 publication Critical patent/BR112015012711B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/70Non-animal cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Developmental Biology & Embryology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

resumo patente de invenção: "método de produção de uma vacina de mycoplasma". a presente invenção refere-se a um método para a preparação de uma composição imunogênica para o tratamento e/ou a profilaxia de infecções por mycoplasma em um indivíduo, o qual compreende o cultivo de bactérias de mycoplasma em um sistema de células eucarióticas com soro reduzido ou livre de soro de suíno; a obtenção de um antígeno das bactérias de mycoplasma; e a adição de um carreador farmaceuticamente aceitável. além disso, a presente invenção refere-se à composição imunogênica que pode ser obtida pelo dito método e a um método para a imunização de um indivíduo que compreende a administração da dita composição imunogênica a um indivíduo.
BR112015012711-8A 2012-12-28 2013-12-20 Método para preparar uma composição imunogênica para o tratamento e/ou a profilaxia de infecções por mycoplasma BR112015012711B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261746997P 2012-12-28 2012-12-28
US61/746,997 2012-12-28
PCT/US2013/076807 WO2014105672A1 (en) 2012-12-28 2013-12-20 Method of making a mycoplasma vaccine

Publications (2)

Publication Number Publication Date
BR112015012711A2 true BR112015012711A2 (pt) 2017-07-11
BR112015012711B1 BR112015012711B1 (pt) 2022-08-16

Family

ID=49917778

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015012711-8A BR112015012711B1 (pt) 2012-12-28 2013-12-20 Método para preparar uma composição imunogênica para o tratamento e/ou a profilaxia de infecções por mycoplasma

Country Status (23)

Country Link
US (2) US9273281B2 (pt)
EP (1) EP2938747B1 (pt)
JP (2) JP6122146B2 (pt)
KR (1) KR102153275B1 (pt)
CN (2) CN104968365B (pt)
AR (1) AR094648A1 (pt)
AU (1) AU2013370983B2 (pt)
BR (1) BR112015012711B1 (pt)
CA (1) CA2896298C (pt)
CL (1) CL2015001562A1 (pt)
DK (1) DK2938747T3 (pt)
EA (1) EA032772B1 (pt)
ES (1) ES2738100T3 (pt)
HU (1) HUE045015T2 (pt)
MX (1) MX361273B (pt)
MY (1) MY173223A (pt)
PH (1) PH12015501333A1 (pt)
PL (1) PL2938747T3 (pt)
PT (1) PT2938747T (pt)
SG (2) SG11201505089YA (pt)
TW (2) TWI660736B (pt)
UA (1) UA121193C2 (pt)
WO (1) WO2014105672A1 (pt)

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US8546149B2 (en) 2010-08-27 2013-10-01 Intervet Inc. Potency test for vaccine formulations
WO2014105671A1 (en) * 2012-12-28 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition comprising mycoplasma antigens
WO2014105672A1 (en) * 2012-12-28 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Method of making a mycoplasma vaccine
CN105441368B (zh) * 2016-01-19 2019-01-01 福清市默克兽医院 一株牛支原体及其应用
US10222383B2 (en) 2016-01-29 2019-03-05 Advanced Animal Diagnostics, Inc. Methods and compositions for detecting mycoplasma exposure
RU2724549C1 (ru) * 2016-08-09 2020-06-23 Эгрикалчурал Текнолоджи Рисерч Инститьют Композиция для профилактики и лечения инфекции mycoplasma hyorhinis и способ получения указанной композиции
WO2018144909A1 (en) * 2017-02-03 2018-08-09 The Administrators Of The Tulane Educational Fund Ophthalmic compositions for therapeutic and prophylactic uses
JP6828745B2 (ja) 2017-05-24 2021-02-10 三菱ケミカル株式会社 シートモールディングコンパウンド、繊維強化複合材料および繊維強化複合材料の製造方法
JP2022536410A (ja) 2019-06-10 2022-08-16 エランコ・ユーエス・インコーポレイテッド Mycoplasma培地製剤
CN113201050B (zh) * 2020-08-06 2022-07-22 青岛诺安百特生物技术有限公司 一种金黄色葡萄球菌噬菌体穿孔素及其制备方法和应用

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Also Published As

Publication number Publication date
ES2738100T3 (es) 2020-01-20
SG11201505089YA (en) 2015-07-30
CL2015001562A1 (es) 2016-06-24
CN108379571A (zh) 2018-08-10
BR112015012711B1 (pt) 2022-08-16
PT2938747T (pt) 2019-08-01
JP2017145253A (ja) 2017-08-24
CN104968365A (zh) 2015-10-07
KR20150100920A (ko) 2015-09-02
EP2938747B1 (en) 2019-05-01
AU2013370983B2 (en) 2019-09-26
US20160136254A1 (en) 2016-05-19
JP2016508983A (ja) 2016-03-24
PL2938747T3 (pl) 2019-11-29
JP6122146B2 (ja) 2017-04-26
HUE045015T2 (hu) 2019-11-28
EA032772B1 (ru) 2019-07-31
AU2013370983A1 (en) 2015-05-21
KR102153275B1 (ko) 2020-09-09
UA121193C2 (uk) 2020-04-27
MY173223A (en) 2020-01-07
EP2938747A1 (en) 2015-11-04
US20140186394A1 (en) 2014-07-03
TW201832777A (zh) 2018-09-16
MX2015007730A (es) 2015-09-07
EA201500701A1 (ru) 2015-12-30
CA2896298C (en) 2024-01-16
PH12015501333A1 (en) 2015-09-02
CN104968365B (zh) 2018-04-03
JP6449364B2 (ja) 2019-01-09
US9273281B2 (en) 2016-03-01
AR094648A1 (es) 2015-08-19
MX361273B (es) 2018-12-03
SG10201708028VA (en) 2017-10-30
TW201438732A (zh) 2014-10-16
WO2014105672A1 (en) 2014-07-03
TWI660736B (zh) 2019-06-01
TWI618542B (zh) 2018-03-21
CA2896298A1 (en) 2014-07-03
DK2938747T3 (da) 2019-08-05
US10512680B2 (en) 2019-12-24

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