BR112014031407B1 - Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente - Google Patents

Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente Download PDF

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BR112014031407B1
BR112014031407B1 BR112014031407-1A BR112014031407A BR112014031407B1 BR 112014031407 B1 BR112014031407 B1 BR 112014031407B1 BR 112014031407 A BR112014031407 A BR 112014031407A BR 112014031407 B1 BR112014031407 B1 BR 112014031407B1
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Brazil
Prior art keywords
intensity
polarization
anisotropy
fluid sample
fluorescence light
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BR112014031407-1A
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English (en)
Portuguese (pt)
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BR112014031407A2 (pt
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Andreas Maierhofer
Alfred Gagel
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Fresenius Medical Care Deutschland Gmbh
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Publication of BR112014031407A2 publication Critical patent/BR112014031407A2/pt
Publication of BR112014031407B1 publication Critical patent/BR112014031407B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6866Extracorporeal blood circuits, e.g. dialysis circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1603Regulation parameters
    • A61M1/1605Physical characteristics of the dialysate fluid
    • A61M1/1609Physical characteristics of the dialysate fluid after use, i.e. downstream of dialyser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1619Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403Regulation parameters
    • A61M1/3406Physical characteristics of the filtrate, e.g. urea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Power Engineering (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
BR112014031407-1A 2012-06-15 2013-06-14 Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente BR112014031407B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261660016P 2012-06-15 2012-06-15
US61/660,016 2012-06-15
EP12172251.6A EP2674103A1 (en) 2012-06-15 2012-06-15 Method and device for monitoring an extracorporeal blood treatment of a patient
EP12172251.6 2012-06-15
PCT/EP2013/062366 WO2013186357A1 (en) 2012-06-15 2013-06-14 Method and device for monitoring an extracorporeal blood treatment of a patient

Publications (2)

Publication Number Publication Date
BR112014031407A2 BR112014031407A2 (pt) 2017-06-27
BR112014031407B1 true BR112014031407B1 (pt) 2021-12-28

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BR112014031407-1A BR112014031407B1 (pt) 2012-06-15 2013-06-14 Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente

Country Status (11)

Country Link
US (1) US10010289B2 (enExample)
EP (2) EP2674103A1 (enExample)
JP (1) JP6242883B2 (enExample)
KR (1) KR102058260B1 (enExample)
CN (1) CN104363820B (enExample)
AU (1) AU2013276453B2 (enExample)
BR (1) BR112014031407B1 (enExample)
CA (1) CA2876542C (enExample)
EA (1) EA028556B1 (enExample)
IN (1) IN2015DN00165A (enExample)
WO (1) WO2013186357A1 (enExample)

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JP6303555B2 (ja) * 2014-02-04 2018-04-04 株式会社ジェイ・エム・エス アルブミン濃度測定装置及びアルブミン濃度測定方法
EP3539586B1 (en) 2014-10-10 2022-08-24 NxStage Medical Inc. Flow balancing methods
JP6595204B2 (ja) * 2015-04-24 2019-10-23 株式会社島津製作所 光学分析装置
WO2017165887A1 (en) * 2016-03-25 2017-09-28 The General Hospital Corporation Polarization-based fluorescent nucleic acid detection
EP4052737A1 (en) 2016-07-18 2022-09-07 NxStage Medical Inc. Flow balancing devices, methods, and systems
US11865243B2 (en) 2016-08-30 2024-01-09 Nxstage Medical, Inc. Parameter monitoring in medical treatment systems
US11826545B2 (en) 2016-09-08 2023-11-28 Fresenius Medical Care Holdings, Inc. Optical blood detection system
EP3641850B1 (en) 2017-06-24 2024-10-09 NxStage Medical Inc. Peritoneal dialysis fluid preparation systems
DE102017114735B4 (de) * 2017-06-30 2019-07-04 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Desinfektion
EP3692347B1 (en) * 2017-10-06 2024-03-27 Bio-Rad Laboratories, Inc. Protein quantitation devices and method
JP6997582B2 (ja) * 2017-10-17 2022-01-17 日機装株式会社 血液浄化装置
JP2021516089A (ja) 2018-02-28 2021-07-01 ネクステージ メディカル インコーポレイテッド 流体調製および処置装置、方法、およびシステム
WO2020056808A1 (zh) * 2018-09-21 2020-03-26 北京大学深圳医院 血液中吲哚氰绿的检测装置及系统
CA3138773A1 (en) 2019-05-23 2020-11-26 Nxstage Medical, Inc. Flow synchronization devices, methods and systems
CN113994193B (zh) * 2019-06-26 2025-04-04 旭化成医疗株式会社 浓度计算装置和血液处理系统
CN110691153B (zh) * 2019-08-27 2020-09-22 珠海格力电器股份有限公司 一种显示模组及终端
US12228564B2 (en) 2020-01-10 2025-02-18 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
JP7680430B2 (ja) * 2020-03-31 2025-05-20 旭化成メディカル株式会社 血液浄化システム、制御方法、制御プログラム、学習装置及び学習方法
US12036344B2 (en) * 2020-11-13 2024-07-16 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
DE102021113519A1 (de) * 2021-05-26 2022-12-01 B.Braun Avitum Ag Optischer Sensor zur Bestimmung einer Dialysedosis
JP7754735B2 (ja) * 2022-02-01 2025-10-15 日機装株式会社 透析排液用成分測定装置及び方法
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Publication number Publication date
CN104363820B (zh) 2019-07-05
EP2674103A1 (en) 2013-12-18
JP2015521492A (ja) 2015-07-30
CA2876542A1 (en) 2013-12-19
CA2876542C (en) 2020-08-18
IN2015DN00165A (enExample) 2015-06-12
WO2013186357A1 (en) 2013-12-19
BR112014031407A2 (pt) 2017-06-27
EP2861127A1 (en) 2015-04-22
CN104363820A (zh) 2015-02-18
KR20150024405A (ko) 2015-03-06
AU2013276453A1 (en) 2015-01-22
EA028556B1 (ru) 2017-11-30
AU2013276453B2 (en) 2017-08-17
EA201492106A1 (ru) 2015-05-29
JP6242883B2 (ja) 2017-12-06
KR102058260B1 (ko) 2019-12-20
US10010289B2 (en) 2018-07-03
EP2861127B1 (en) 2020-09-09
US20140046150A1 (en) 2014-02-13

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
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