BR112014011186A2 - espumas de fibroína de seda injetáveis e usos das mesmas - Google Patents
espumas de fibroína de seda injetáveis e usos das mesmasInfo
- Publication number
- BR112014011186A2 BR112014011186A2 BR112014011186A BR112014011186A BR112014011186A2 BR 112014011186 A2 BR112014011186 A2 BR 112014011186A2 BR 112014011186 A BR112014011186 A BR 112014011186A BR 112014011186 A BR112014011186 A BR 112014011186A BR 112014011186 A2 BR112014011186 A2 BR 112014011186A2
- Authority
- BR
- Brazil
- Prior art keywords
- tissue
- silk fibroin
- compositions
- injectable
- injection
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Abstract
resumo espumas de fibroína de seda injetáveis e usos das mesmas os inventos aqui apresentados referem-se a composições, métodos, dispositivos de entrega e kits para reparar ou aumentar um tecido num sujeito. as composições aqui descritas podem ser injetáveis de tal modo que eles podem ser colocados em um tecido a ser tratado com um procedimento minimamente invasivo (por exemplo, por injeção). em algumas formas de realização, a composição aqui descrita compreende uma matriz de fibroína de seda compactada, que pode expandir-se após a injeção no tecido e manter o seu volume expandido original no interior do tecido para um período de tempo. as composições podem ser usadas como material de enchimento para substituir o vazio do tecido, por exemplo, para a reparação e / ou o aumento do tecido, ou como um andaime para apoiar a regeneração e / ou reconstrução de tecidos. em algumas concretizações, as composições aqui descritas podem ser utilizadas para a reparação de tecidos moles ou de aumento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161557610P | 2011-11-09 | 2011-11-09 | |
PCT/US2012/064471 WO2013071123A1 (en) | 2011-11-09 | 2012-11-09 | Injectable silk fibroin foams and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014011186A2 true BR112014011186A2 (pt) | 2017-05-09 |
Family
ID=48290613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014011186A BR112014011186A2 (pt) | 2011-11-09 | 2012-11-09 | espumas de fibroína de seda injetáveis e usos das mesmas |
Country Status (11)
Country | Link |
---|---|
US (3) | US9492504B2 (pt) |
EP (2) | EP2776079B1 (pt) |
JP (5) | JP6266525B2 (pt) |
KR (3) | KR102344643B1 (pt) |
CN (1) | CN104203292B (pt) |
AU (2) | AU2012335122B2 (pt) |
BR (1) | BR112014011186A2 (pt) |
CA (1) | CA2890372A1 (pt) |
ES (1) | ES2791769T3 (pt) |
MX (1) | MX2014005704A (pt) |
WO (1) | WO2013071123A1 (pt) |
Families Citing this family (22)
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WO2013071107A1 (en) * | 2011-11-09 | 2013-05-16 | Trustees Of Tufts College | Injectable silk fibroin particles and uses thereof |
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KR102385695B1 (ko) * | 2021-04-15 | 2022-04-12 | 남기준 | 세미-아이피엔 구조를 이루는 연조직 수복 및 확대를 위한 신규한 히알루론-복합 아미노 하이드로 겔 조성물 및 이의 용도 |
KR102509832B1 (ko) * | 2022-02-23 | 2023-03-14 | 주식회사 지씨에스 | 상이한 구조를 이루는 다분산 펩타이드 기반의 최소 침습 임플란트가 가능한 하이드로겔 조성물 및 그의 용도 |
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KR101176793B1 (ko) * | 2010-05-03 | 2012-09-07 | 대한민국(농촌진흥청장) | 실크 피브로인 가수분해물과 pmma를 함유하는 생체적합성 골 시멘트 조성물 |
KR102344643B1 (ko) | 2011-11-09 | 2021-12-30 | 트러스티즈 오브 터프츠 칼리지 | 주사가능한 실크 피브로인 발포체 및 그의 용도 |
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2012
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- 2012-11-09 WO PCT/US2012/064471 patent/WO2013071123A1/en active Application Filing
- 2012-11-09 BR BR112014011186A patent/BR112014011186A2/pt not_active Application Discontinuation
- 2012-11-09 JP JP2014541331A patent/JP6266525B2/ja active Active
- 2012-11-09 CA CA2890372A patent/CA2890372A1/en not_active Abandoned
- 2012-11-09 US US14/357,420 patent/US9492504B2/en active Active
- 2012-11-09 KR KR1020217042367A patent/KR20220002711A/ko not_active Application Discontinuation
- 2012-11-09 KR KR1020147015571A patent/KR102176406B1/ko active IP Right Grant
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- 2012-11-09 CN CN201280066539.6A patent/CN104203292B/zh active Active
- 2012-11-09 MX MX2014005704A patent/MX2014005704A/es unknown
- 2012-11-09 EP EP12846855.0A patent/EP2776079B1/en active Active
- 2012-11-09 AU AU2012335122A patent/AU2012335122B2/en active Active
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2016
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2019
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2021
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CA2890372A1 (en) | 2013-05-16 |
JP2023105131A (ja) | 2023-07-28 |
JP2015501670A (ja) | 2015-01-19 |
US11701450B2 (en) | 2023-07-18 |
AU2012335122A1 (en) | 2014-06-26 |
CN104203292B (zh) | 2019-05-31 |
JP2018086270A (ja) | 2018-06-07 |
US20170007738A1 (en) | 2017-01-12 |
EP2776079A4 (en) | 2015-05-27 |
AU2012335122B2 (en) | 2016-09-22 |
EP2776079B1 (en) | 2020-04-01 |
MX2014005704A (es) | 2015-02-17 |
KR102344643B1 (ko) | 2021-12-30 |
US20240123117A1 (en) | 2024-04-18 |
CN104203292A (zh) | 2014-12-10 |
EP3750567A1 (en) | 2020-12-16 |
JP2019195729A (ja) | 2019-11-14 |
US9492504B2 (en) | 2016-11-15 |
JP6266525B2 (ja) | 2018-01-24 |
EP2776079A1 (en) | 2014-09-17 |
KR20200128597A (ko) | 2020-11-13 |
KR20220002711A (ko) | 2022-01-06 |
US20140314817A1 (en) | 2014-10-23 |
AU2016269487A1 (en) | 2017-01-05 |
WO2013071123A1 (en) | 2013-05-16 |
JP2021164731A (ja) | 2021-10-14 |
JP6913134B2 (ja) | 2021-08-04 |
ES2791769T3 (es) | 2020-11-05 |
KR20140091585A (ko) | 2014-07-21 |
KR102176406B1 (ko) | 2020-11-09 |
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