BR112014010053A8 - variantes de isopreno sintase com solubilidade aprimorada para produção de isopreno - Google Patents
variantes de isopreno sintase com solubilidade aprimorada para produção de isoprenoInfo
- Publication number
- BR112014010053A8 BR112014010053A8 BR112014010053A BR112014010053A BR112014010053A8 BR 112014010053 A8 BR112014010053 A8 BR 112014010053A8 BR 112014010053 A BR112014010053 A BR 112014010053A BR 112014010053 A BR112014010053 A BR 112014010053A BR 112014010053 A8 BR112014010053 A8 BR 112014010053A8
- Authority
- BR
- Brazil
- Prior art keywords
- isoprene
- production
- present
- enhanced solubility
- isoprene synthase
- Prior art date
Links
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 title abstract 8
- 108010075483 isoprene synthase Proteins 0.000 title abstract 6
- 230000000694 effects Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03007—Pentalenene synthase (4.2.3.7)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L7/00—Compositions of natural rubber
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552453P | 2011-10-27 | 2011-10-27 | |
| PCT/US2012/062308 WO2013063528A2 (en) | 2011-10-27 | 2012-10-26 | Isoprene synthase variants with improved solubility for production of isoprene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014010053A2 BR112014010053A2 (pt) | 2017-06-13 |
| BR112014010053A8 true BR112014010053A8 (pt) | 2017-06-20 |
Family
ID=47178953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014010053A BR112014010053A8 (pt) | 2011-10-27 | 2012-10-26 | variantes de isopreno sintase com solubilidade aprimorada para produção de isopreno |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8735134B2 (enExample) |
| EP (1) | EP2771460B1 (enExample) |
| JP (1) | JP6101275B2 (enExample) |
| BR (1) | BR112014010053A8 (enExample) |
| CA (1) | CA2853125A1 (enExample) |
| DK (1) | DK2771460T3 (enExample) |
| HK (1) | HK1201554A1 (enExample) |
| WO (1) | WO2013063528A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2737082A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
| EP2771460B1 (en) | 2011-10-27 | 2017-04-26 | Danisco US Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
| EP2794851A2 (en) * | 2011-12-23 | 2014-10-29 | Danisco US Inc. | Enhanced production of isoprene using marine bacterial cells |
| EP2913392B1 (en) * | 2012-10-23 | 2023-06-07 | Sekisui Chemical Co., Ltd. | Recombinant cell and production method for isoprene |
| MY172689A (en) | 2013-11-22 | 2019-12-10 | Ajinomoto Kk | Modified isoprene synthase |
| CN105985971B (zh) * | 2015-02-10 | 2021-01-22 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8407828D0 (en) | 1984-03-27 | 1984-05-02 | Ontario Research Foundation | In situ preparation |
| US4570029A (en) | 1985-03-04 | 1986-02-11 | Uop Inc. | Process for separating isoprene |
| US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
| US5849970A (en) | 1995-06-23 | 1998-12-15 | The Regents Of The University Of Colorado | Materials and methods for the bacterial production of isoprene |
| DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
| US6176176B1 (en) | 1998-04-30 | 2001-01-23 | Board Of Trustees Operating Michigan State University | Apparatus for treating cellulosic materials |
| US20030033626A1 (en) | 2000-07-31 | 2003-02-13 | Hahn Frederick M. | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| JP4592418B2 (ja) | 2002-10-04 | 2010-12-01 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 高収率での１，３−プロパンジオールの生物生産のための方法 |
| US7947478B2 (en) | 2006-06-29 | 2011-05-24 | The Regents Of The University Of California | Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria |
| JP4986547B2 (ja) | 2006-09-04 | 2012-07-25 | 株式会社Ａｄｅｋａ | 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法 |
| US20090076743A1 (en) | 2007-08-01 | 2009-03-19 | Drexel University | Novel method for zero point detection |
| SG162265A1 (en) | 2007-12-13 | 2010-07-29 | Danisco Us Inc | Compositions and methods for producing isoprene |
| AU2009240505B2 (en) | 2008-04-23 | 2013-09-05 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
| US8420759B2 (en) | 2008-06-30 | 2013-04-16 | The Goodyear Tire & Rubber Company | Polymers of isoprene from renewable resources |
| AU2009266938B2 (en) | 2008-07-02 | 2013-10-17 | Danisco Us Inc. | Compositions and methods for producing isoprene free of C5 hydrocarbons under decoupling conditions and/or safe operating ranges |
| CA2737082A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
| SG169614A1 (en) | 2008-09-15 | 2011-04-29 | Goodyear Tire & Rubber | Conversion of prenyl derivatives to isoprene |
| CA2737158A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using the archaeal lower mevalonate pathway |
| MY156588A (en) | 2008-09-15 | 2016-03-15 | Danisco Us Inc | Systems using cell culture for production of isoprene |
| CA2737223A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| BRPI0923828A2 (pt) | 2008-12-30 | 2019-09-24 | Danisco Us Inc. | método de produção de isopreno e um co-produto. |
| CA2759700A1 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| TW201120213A (en) | 2009-06-17 | 2011-06-16 | Danisco Us Inc | Polymerization of isoprene from renewable resources |
| TWI427149B (zh) | 2009-06-17 | 2014-02-21 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| BR112012014736B1 (pt) | 2009-12-18 | 2018-09-18 | Danisco Us Inc | método para purificação de isopreno a partir de um efluente gasoso do fermentador e composição |
| BR112012015117A2 (pt) | 2009-12-22 | 2019-09-24 | Danisco Us Inc | "biorreator de membrana para produção aumentada de gás isopreno" |
| BR112012017345A2 (pt) | 2009-12-23 | 2015-11-03 | Danisco Us Inc | "composições e métodos de pgl para a produção aumentada de isopreno e outros produtos com 6-fosfogliconolactonase (pgl)" |
| US9273298B2 (en) * | 2010-10-27 | 2016-03-01 | Danisco Us Inc. | Isoprene synthase variants for improved production of isoprene |
| EP2771460B1 (en) | 2011-10-27 | 2017-04-26 | Danisco US Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
-
2012
- 2012-10-26 EP EP12787268.7A patent/EP2771460B1/en not_active Not-in-force
- 2012-10-26 CA CA2853125A patent/CA2853125A1/en not_active Abandoned
- 2012-10-26 JP JP2014539095A patent/JP6101275B2/ja not_active Expired - Fee Related
- 2012-10-26 HK HK15101956.3A patent/HK1201554A1/xx unknown
- 2012-10-26 BR BR112014010053A patent/BR112014010053A8/pt not_active Application Discontinuation
- 2012-10-26 US US13/662,328 patent/US8735134B2/en not_active Expired - Fee Related
- 2012-10-26 DK DK12787268.7T patent/DK2771460T3/en active
- 2012-10-26 WO PCT/US2012/062308 patent/WO2013063528A2/en not_active Ceased
-
2014
- 2014-04-11 US US14/251,311 patent/US9273299B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013063528A2 (en) | 2013-05-02 |
| DK2771460T3 (en) | 2017-06-06 |
| EP2771460B1 (en) | 2017-04-26 |
| JP6101275B2 (ja) | 2017-03-22 |
| CA2853125A1 (en) | 2013-05-02 |
| JP2015503904A (ja) | 2015-02-05 |
| US20140315275A1 (en) | 2014-10-23 |
| US8735134B2 (en) | 2014-05-27 |
| BR112014010053A2 (pt) | 2017-06-13 |
| WO2013063528A3 (en) | 2013-06-20 |
| US20130295632A1 (en) | 2013-11-07 |
| HK1201554A1 (en) | 2015-09-04 |
| US9273299B2 (en) | 2016-03-01 |
| EP2771460A2 (en) | 2014-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |