DK2771460T3 - ISOPRENE SYNTHASE VARIETIES WITH IMPROVED SOLUBILITY FOR THE PREPARATION OF ISOPRENE - Google Patents
ISOPRENE SYNTHASE VARIETIES WITH IMPROVED SOLUBILITY FOR THE PREPARATION OF ISOPRENE Download PDFInfo
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- DK2771460T3 DK2771460T3 DK12787268.7T DK12787268T DK2771460T3 DK 2771460 T3 DK2771460 T3 DK 2771460T3 DK 12787268 T DK12787268 T DK 12787268T DK 2771460 T3 DK2771460 T3 DK 2771460T3
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- polypeptide
- isoprene
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03007—Pentalenene synthase (4.2.3.7)
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L7/00—Compositions of natural rubber
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- Genetics & Genomics (AREA)
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- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552453P | 2011-10-27 | 2011-10-27 | |
| PCT/US2012/062308 WO2013063528A2 (en) | 2011-10-27 | 2012-10-26 | Isoprene synthase variants with improved solubility for production of isoprene |
Publications (1)
| Publication Number | Publication Date |
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| DK2771460T3 true DK2771460T3 (en) | 2017-06-06 |
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Family Applications (1)
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| DK12787268.7T DK2771460T3 (en) | 2011-10-27 | 2012-10-26 | ISOPRENE SYNTHASE VARIETIES WITH IMPROVED SOLUBILITY FOR THE PREPARATION OF ISOPRENE |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8735134B2 (enExample) |
| EP (1) | EP2771460B1 (enExample) |
| JP (1) | JP6101275B2 (enExample) |
| BR (1) | BR112014010053A8 (enExample) |
| CA (1) | CA2853125A1 (enExample) |
| DK (1) | DK2771460T3 (enExample) |
| HK (1) | HK1201554A1 (enExample) |
| WO (1) | WO2013063528A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2737082A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
| WO2013063528A2 (en) | 2011-10-27 | 2013-05-02 | Danisco Us Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
| EP2794851A2 (en) * | 2011-12-23 | 2014-10-29 | Danisco US Inc. | Enhanced production of isoprene using marine bacterial cells |
| CN111621453A (zh) * | 2012-10-23 | 2020-09-04 | 积水化学工业株式会社 | 重组细胞以及异戊二烯的生产方法 |
| MY172689A (en) | 2013-11-22 | 2019-12-10 | Ajinomoto Kk | Modified isoprene synthase |
| CN105985971B (zh) * | 2015-02-10 | 2021-01-22 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
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| GB8407828D0 (en) | 1984-03-27 | 1984-05-02 | Ontario Research Foundation | In situ preparation |
| US4570029A (en) | 1985-03-04 | 1986-02-11 | Uop Inc. | Process for separating isoprene |
| US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
| US5849970A (en) | 1995-06-23 | 1998-12-15 | The Regents Of The University Of Colorado | Materials and methods for the bacterial production of isoprene |
| DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
| US6176176B1 (en) | 1998-04-30 | 2001-01-23 | Board Of Trustees Operating Michigan State University | Apparatus for treating cellulosic materials |
| US20030033626A1 (en) | 2000-07-31 | 2003-02-13 | Hahn Frederick M. | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| AU2003287028B2 (en) | 2002-10-04 | 2008-09-04 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| US7947478B2 (en) | 2006-06-29 | 2011-05-24 | The Regents Of The University Of California | Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria |
| JP4986547B2 (ja) | 2006-09-04 | 2012-07-25 | 株式会社Ａｄｅｋａ | 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法 |
| US20090076743A1 (en) | 2007-08-01 | 2009-03-19 | Drexel University | Novel method for zero point detection |
| BRPI0823506A8 (pt) | 2007-12-13 | 2018-05-15 | Danisco Us Inc Genencor Div | composições e métodos para a produção de isoprene |
| JP2011518564A (ja) * | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
| SG167485A1 (en) | 2008-06-30 | 2011-01-28 | Danisco Us Inc | Polymers of isoprene from renewable resources |
| EP2310490B1 (en) | 2008-07-02 | 2019-01-02 | Danisco US Inc. | Methods for producing isoprene |
| CA2737082A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
| CA2737223A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| MY156562A (en) | 2008-09-15 | 2016-02-26 | Danisco Us Inc | Increased isoprene production using the archaeal lower mevalonate pathway |
| BRPI0918936A2 (pt) | 2008-09-15 | 2019-09-24 | Danisco Us Inc | conversão de derivados de prenila em isopreno |
| WO2010031079A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Systems using cell culture for production of isoprene |
| CN102333866B (zh) | 2008-12-30 | 2015-04-29 | 丹尼斯科美国公司 | 生产异戊二烯和共同产物的方法 |
| EP2421966A2 (en) | 2009-04-23 | 2012-02-29 | Danisco US Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| TW201412988A (zh) | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| TW201120213A (en) | 2009-06-17 | 2011-06-16 | Danisco Us Inc | Polymerization of isoprene from renewable resources |
| CN102884028B (zh) | 2009-12-18 | 2015-08-19 | 丹尼斯科美国公司 | 从可再生资源中纯化异戊二烯 |
| CA2785530A1 (en) | 2009-12-22 | 2011-06-23 | Danisco Us Inc. | Membrane bioreactor for increased production of isoprene gas |
| AU2010336342B2 (en) | 2009-12-23 | 2015-02-26 | Danisco Us Inc. | Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (PGL) |
| JP2014502148A (ja) * | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | イソプレン生産の向上を目的としたイソプレン合成酵素変異体 |
| WO2013063528A2 (en) | 2011-10-27 | 2013-05-02 | Danisco Us Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
-
2012
- 2012-10-26 WO PCT/US2012/062308 patent/WO2013063528A2/en not_active Ceased
- 2012-10-26 HK HK15101956.3A patent/HK1201554A1/xx unknown
- 2012-10-26 US US13/662,328 patent/US8735134B2/en not_active Expired - Fee Related
- 2012-10-26 BR BR112014010053A patent/BR112014010053A8/pt not_active Application Discontinuation
- 2012-10-26 JP JP2014539095A patent/JP6101275B2/ja not_active Expired - Fee Related
- 2012-10-26 EP EP12787268.7A patent/EP2771460B1/en not_active Not-in-force
- 2012-10-26 DK DK12787268.7T patent/DK2771460T3/en active
- 2012-10-26 CA CA2853125A patent/CA2853125A1/en not_active Abandoned
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2014
- 2014-04-11 US US14/251,311 patent/US9273299B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014010053A2 (pt) | 2017-06-13 |
| JP6101275B2 (ja) | 2017-03-22 |
| WO2013063528A2 (en) | 2013-05-02 |
| US20140315275A1 (en) | 2014-10-23 |
| JP2015503904A (ja) | 2015-02-05 |
| EP2771460B1 (en) | 2017-04-26 |
| WO2013063528A3 (en) | 2013-06-20 |
| US9273299B2 (en) | 2016-03-01 |
| CA2853125A1 (en) | 2013-05-02 |
| HK1201554A1 (en) | 2015-09-04 |
| US8735134B2 (en) | 2014-05-27 |
| EP2771460A2 (en) | 2014-09-03 |
| BR112014010053A8 (pt) | 2017-06-20 |
| US20130295632A1 (en) | 2013-11-07 |
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