BR112014008225A2 - sistemas de purificação de vetores virais - Google Patents
sistemas de purificação de vetores viraisInfo
- Publication number
- BR112014008225A2 BR112014008225A2 BR112014008225A BR112014008225A BR112014008225A2 BR 112014008225 A2 BR112014008225 A2 BR 112014008225A2 BR 112014008225 A BR112014008225 A BR 112014008225A BR 112014008225 A BR112014008225 A BR 112014008225A BR 112014008225 A2 BR112014008225 A2 BR 112014008225A2
- Authority
- BR
- Brazil
- Prior art keywords
- viral vector
- purification systems
- purification
- viral
- vector purification
- Prior art date
Links
- 238000000746 purification Methods 0.000 title abstract 4
- 239000013603 viral vector Substances 0.000 title abstract 3
- 239000002458 cell surface marker Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 241000712907 Retroviridae Species 0.000 abstract 1
- 108010003533 Viral Envelope Proteins Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 210000004779 membrane envelope Anatomy 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13051—Methods of production or purification of viral material
- C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
- C12N2740/15052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
- C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11183937 | 2011-10-05 | ||
| PCT/EP2012/069713 WO2013050523A1 (en) | 2011-10-05 | 2012-10-05 | Viral vectors purification system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014008225A2 true BR112014008225A2 (pt) | 2017-04-11 |
Family
ID=47071247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014008225A BR112014008225A2 (pt) | 2011-10-05 | 2012-10-05 | sistemas de purificação de vetores virais |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140248695A1 (https=) |
| EP (1) | EP2764094A1 (https=) |
| JP (1) | JP2014528729A (https=) |
| KR (1) | KR20140068259A (https=) |
| CN (1) | CN103842501B (https=) |
| AU (1) | AU2012320480A1 (https=) |
| BR (1) | BR112014008225A2 (https=) |
| CA (1) | CA2848939A1 (https=) |
| IL (1) | IL231876A0 (https=) |
| IN (1) | IN2014CN03368A (https=) |
| RU (1) | RU2607044C2 (https=) |
| WO (1) | WO2013050523A1 (https=) |
| ZA (1) | ZA201401481B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2480677T3 (en) | 2010-09-02 | 2015-06-15 | Molmed Spa | Semi-stable production of lentiviral vectors |
| GB201310664D0 (en) | 2013-06-14 | 2013-07-31 | Mars Inc | Feline taste receptors |
| BR112018070256A2 (pt) | 2016-03-31 | 2019-01-29 | Spark Therapeutics, Inc. | processo de fabricação de raav totalmente escalável à base de colunas |
| JP2025143019A (ja) * | 2024-03-18 | 2025-10-01 | アイポア株式会社 | ウイルスベクターの検査方法及び機械学習システム |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5654183A (en) * | 1992-07-27 | 1997-08-05 | California Institute Of Technology | Genetically engineered mammalian neural crest stem cells |
| IT1261847B (it) | 1993-09-01 | 1996-06-03 | San Romanello Centro Fond | Metodo per marcare cellule eucariote. |
| EP0781343B1 (de) * | 1994-09-08 | 2003-07-02 | Vision 7 GmbH | Retrovirale vektorhybride und deren verwendung zum gentransfer |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| EP1284287A4 (en) * | 2000-05-10 | 2004-10-13 | Mitsubishi Pharma Corp | METHOD FOR PRODUCING A VIRUS VECTOR |
| IL154987A0 (en) * | 2000-09-22 | 2003-10-31 | Virxsys | Conditionally replicating viral vectors and their use |
| GB0224442D0 (en) * | 2002-10-21 | 2002-11-27 | Molmed Spa | A delivery system |
| GB0413702D0 (en) | 2004-06-18 | 2004-07-21 | Molmed Spa | Thymidine kinase |
| JP3968383B2 (ja) * | 2004-09-01 | 2007-08-29 | 株式会社日本メディカル総研 | 血液細胞の新規分類法ならびにそれを利用したテイラーメード治療および予防 |
| EP1739180A1 (en) * | 2005-06-27 | 2007-01-03 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | T cell line-based packaging cell line for the production of retroviruses by enriching of CD3 expressing cells |
| JP4921083B2 (ja) * | 2005-09-13 | 2012-04-18 | タカラバイオ株式会社 | レトロウィルス産生用無血清培地 |
| WO2011060218A1 (en) * | 2009-11-13 | 2011-05-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modulated programmed death ligand-1 |
| GB0920775D0 (en) * | 2009-11-26 | 2010-01-13 | King S College | Cells |
| DK2480677T3 (en) | 2010-09-02 | 2015-06-15 | Molmed Spa | Semi-stable production of lentiviral vectors |
| WO2012028680A1 (en) | 2010-09-02 | 2012-03-08 | Molmed Spa | Semi-stable production of lentiviral vectors |
-
2012
- 2012-10-05 AU AU2012320480A patent/AU2012320480A1/en not_active Abandoned
- 2012-10-05 CN CN201280049032.XA patent/CN103842501B/zh not_active Expired - Fee Related
- 2012-10-05 EP EP12775654.2A patent/EP2764094A1/en not_active Withdrawn
- 2012-10-05 RU RU2014117466A patent/RU2607044C2/ru not_active IP Right Cessation
- 2012-10-05 JP JP2014533916A patent/JP2014528729A/ja not_active Ceased
- 2012-10-05 BR BR112014008225A patent/BR112014008225A2/pt not_active IP Right Cessation
- 2012-10-05 WO PCT/EP2012/069713 patent/WO2013050523A1/en not_active Ceased
- 2012-10-05 KR KR1020147011842A patent/KR20140068259A/ko not_active Ceased
- 2012-10-05 US US14/349,531 patent/US20140248695A1/en not_active Abandoned
- 2012-10-05 IN IN3368CHN2014 patent/IN2014CN03368A/en unknown
- 2012-10-05 CA CA2848939A patent/CA2848939A1/en not_active Abandoned
-
2014
- 2014-02-26 ZA ZA2014/01481A patent/ZA201401481B/en unknown
- 2014-04-02 IL IL231876A patent/IL231876A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20140248695A1 (en) | 2014-09-04 |
| CN103842501B (zh) | 2017-12-08 |
| IL231876A0 (en) | 2014-05-28 |
| AU2012320480A1 (en) | 2014-04-24 |
| WO2013050523A1 (en) | 2013-04-11 |
| JP2014528729A (ja) | 2014-10-30 |
| RU2014117466A (ru) | 2015-11-10 |
| KR20140068259A (ko) | 2014-06-05 |
| ZA201401481B (en) | 2015-04-29 |
| IN2014CN03368A (https=) | 2015-07-03 |
| EP2764094A1 (en) | 2014-08-13 |
| RU2607044C2 (ru) | 2017-01-10 |
| NZ623092A (en) | 2016-07-29 |
| CA2848939A1 (en) | 2013-04-11 |
| CN103842501A (zh) | 2014-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015022292A2 (pt) | processo de fabricação escalonável para produzir vetores lentivirais recombinantes em um sistema de cultura celular em suspensão sem soro | |
| BR112015023489A2 (pt) | uso de rnas-guia truncads (tru - grnas) para aumentar a especificidade de edição de genoma com rna guiado | |
| BR112014019901A8 (pt) | Proteínas de fator viii recombinante | |
| BR112017018885A2 (pt) | método de cultura celular para células-tronco mesenquimais | |
| MX343604B (es) | Disminuir nivel de lactato e incrementar producción de polipéptidos por regulación a la baja de la expresión de lactato dehidrogenasa y piruvato dehidrogenasa quinasa. | |
| GT201400097A (es) | Agentes de iarn, composiciones y métodos de uso de los mismos para tratar enfermedades asociadas con transtiretina (ttr) | |
| AR096270A1 (es) | Composiciones detergentes | |
| DOP2013000240A (es) | Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga | |
| UY34227A (es) | Acido nucleico recombinante que codifica el gen de la toxina axmi270, vectores, células, plantas y sus métodos de empleo | |
| BR112012011740A2 (pt) | polipeptídeo, composição compreendendo o referido polipeptídeo, complexo de proteína, seqüência de nucleotídeo, vetor de expressão célula, e métodos para a preparação do complexo de proteína, para a preparação de um fviii, e para intensificar uma propriedade farmacocinética no plasma de um fviii | |
| MX2019003427A (es) | Composiciones para cultivo celular y metodos para la produccion de polipeptidos. | |
| BR112018077358A2 (pt) | tagatose-6-fosfato fosfatase termoestável inovadora e um método para produzir tagatose com o uso da mesma | |
| MX2016012188A (es) | Anticuerpos antagonistas dirigidos contra el peptido relacionado con el gen de calcitonina y metodos que usan los mismos. | |
| AR075932A1 (es) | Proteasa coagulante de leche de tipo mejorado derivada del microorganismo rhizomucor sp | |
| BR112014014116A2 (pt) | método de floculação | |
| MX2022001017A (es) | Composiciones y metodos para inhibir la expresion del gen de sintasa de acido 5'-aminolevulinico 1 (alas1). | |
| MX2017008410A (es) | Reduccion selectiva de residuos cisteina en anticuerpos il-17. | |
| BR112017020308A2 (pt) | udp-glicosiltransferases | |
| PH12018500155A1 (en) | Recombinant orf virus vector | |
| PE20150603A1 (es) | Metodo para producir iduronato-2-sulfatasa recombinante | |
| BR112014008225A2 (pt) | sistemas de purificação de vetores virais | |
| BR112017013576A2 (pt) | produção melhorada de lipídios de núcleo em leveduras oleaginosas | |
| BR112016015218A2 (pt) | microrganismo com capacidade melhorada de produção de l-treonina e método para produzir l-treonina com o uso desse | |
| MX2015016765A (es) | Celulas aviares para la produccion mejorada de virus. | |
| BR112013027031A2 (pt) | transformação melhorada de monocotiledôneas recalcitrantes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2534 DE 30-07-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |