KR20140068259A - 바이러스 벡터 정제 시스템 - Google Patents

바이러스 벡터 정제 시스템 Download PDF

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Publication number
KR20140068259A
KR20140068259A KR1020147011842A KR20147011842A KR20140068259A KR 20140068259 A KR20140068259 A KR 20140068259A KR 1020147011842 A KR1020147011842 A KR 1020147011842A KR 20147011842 A KR20147011842 A KR 20147011842A KR 20140068259 A KR20140068259 A KR 20140068259A
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KR
South Korea
Prior art keywords
cell surface
viral
ligand
purification
surface marker
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Ceased
Application number
KR1020147011842A
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English (en)
Korean (ko)
Inventor
키아라 보볼렌타
안나 스토르나이유올라
Original Assignee
몰메드 에스피에이
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Application filed by 몰메드 에스피에이 filed Critical 몰메드 에스피에이
Publication of KR20140068259A publication Critical patent/KR20140068259A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13051—Methods of production or purification of viral material
    • C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15051—Methods of production or purification of viral material
    • C12N2740/15052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020147011842A 2011-10-05 2012-10-05 바이러스 벡터 정제 시스템 Ceased KR20140068259A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11183937.9 2011-10-05
EP11183937 2011-10-05
PCT/EP2012/069713 WO2013050523A1 (en) 2011-10-05 2012-10-05 Viral vectors purification system

Publications (1)

Publication Number Publication Date
KR20140068259A true KR20140068259A (ko) 2014-06-05

Family

ID=47071247

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147011842A Ceased KR20140068259A (ko) 2011-10-05 2012-10-05 바이러스 벡터 정제 시스템

Country Status (13)

Country Link
US (1) US20140248695A1 (https=)
EP (1) EP2764094A1 (https=)
JP (1) JP2014528729A (https=)
KR (1) KR20140068259A (https=)
CN (1) CN103842501B (https=)
AU (1) AU2012320480A1 (https=)
BR (1) BR112014008225A2 (https=)
CA (1) CA2848939A1 (https=)
IL (1) IL231876A0 (https=)
IN (1) IN2014CN03368A (https=)
RU (1) RU2607044C2 (https=)
WO (1) WO2013050523A1 (https=)
ZA (1) ZA201401481B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2480677T3 (en) 2010-09-02 2015-06-15 Molmed Spa Semi-stable production of lentiviral vectors
GB201310664D0 (en) 2013-06-14 2013-07-31 Mars Inc Feline taste receptors
BR112018070256A2 (pt) 2016-03-31 2019-01-29 Spark Therapeutics, Inc. processo de fabricação de raav totalmente escalável à base de colunas
JP2025143019A (ja) * 2024-03-18 2025-10-01 アイポア株式会社 ウイルスベクターの検査方法及び機械学習システム

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654183A (en) * 1992-07-27 1997-08-05 California Institute Of Technology Genetically engineered mammalian neural crest stem cells
IT1261847B (it) 1993-09-01 1996-06-03 San Romanello Centro Fond Metodo per marcare cellule eucariote.
EP0781343B1 (de) * 1994-09-08 2003-07-02 Vision 7 GmbH Retrovirale vektorhybride und deren verwendung zum gentransfer
US5837520A (en) * 1995-03-07 1998-11-17 Canji, Inc. Method of purification of viral vectors
EP1284287A4 (en) * 2000-05-10 2004-10-13 Mitsubishi Pharma Corp METHOD FOR PRODUCING A VIRUS VECTOR
IL154987A0 (en) * 2000-09-22 2003-10-31 Virxsys Conditionally replicating viral vectors and their use
GB0224442D0 (en) * 2002-10-21 2002-11-27 Molmed Spa A delivery system
GB0413702D0 (en) 2004-06-18 2004-07-21 Molmed Spa Thymidine kinase
JP3968383B2 (ja) * 2004-09-01 2007-08-29 株式会社日本メディカル総研 血液細胞の新規分類法ならびにそれを利用したテイラーメード治療および予防
EP1739180A1 (en) * 2005-06-27 2007-01-03 Max-Delbrück-Centrum für Molekulare Medizin (MDC) T cell line-based packaging cell line for the production of retroviruses by enriching of CD3 expressing cells
JP4921083B2 (ja) * 2005-09-13 2012-04-18 タカラバイオ株式会社 レトロウィルス産生用無血清培地
WO2011060218A1 (en) * 2009-11-13 2011-05-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Modulated programmed death ligand-1
GB0920775D0 (en) * 2009-11-26 2010-01-13 King S College Cells
DK2480677T3 (en) 2010-09-02 2015-06-15 Molmed Spa Semi-stable production of lentiviral vectors
WO2012028680A1 (en) 2010-09-02 2012-03-08 Molmed Spa Semi-stable production of lentiviral vectors

Also Published As

Publication number Publication date
US20140248695A1 (en) 2014-09-04
CN103842501B (zh) 2017-12-08
IL231876A0 (en) 2014-05-28
AU2012320480A1 (en) 2014-04-24
WO2013050523A1 (en) 2013-04-11
JP2014528729A (ja) 2014-10-30
RU2014117466A (ru) 2015-11-10
ZA201401481B (en) 2015-04-29
IN2014CN03368A (https=) 2015-07-03
EP2764094A1 (en) 2014-08-13
RU2607044C2 (ru) 2017-01-10
NZ623092A (en) 2016-07-29
BR112014008225A2 (pt) 2017-04-11
CA2848939A1 (en) 2013-04-11
CN103842501A (zh) 2014-06-04

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