BR112014007683A2 - preparação ultrar rápida do tecido de diagnóstico como uma alternativa para seção congelada - Google Patents

preparação ultrar rápida do tecido de diagnóstico como uma alternativa para seção congelada

Info

Publication number
BR112014007683A2
BR112014007683A2 BR112014007683A BR112014007683A BR112014007683A2 BR 112014007683 A2 BR112014007683 A2 BR 112014007683A2 BR 112014007683 A BR112014007683 A BR 112014007683A BR 112014007683 A BR112014007683 A BR 112014007683A BR 112014007683 A2 BR112014007683 A2 BR 112014007683A2
Authority
BR
Brazil
Prior art keywords
tissue
module
alternative
frozen section
tissue sample
Prior art date
Application number
BR112014007683A
Other languages
English (en)
Other versions
BR112014007683B1 (pt
Inventor
R Morales Azorides
Original Assignee
The Univ Of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Univ Of Miami filed Critical The Univ Of Miami
Publication of BR112014007683A2 publication Critical patent/BR112014007683A2/pt
Publication of BR112014007683B1 publication Critical patent/BR112014007683B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

resumo patente de invenção: "preparação ultrar rápida do tecido de diagnóstico como uma alternativa para seção congelada". a presente invenção refere-se aos métodos e sistemas aperfeiçoados para processamento de tecidos sólidos. o método pode ser realizado manualmente ou automaticamente. o sistema pode ter módulos, tais como (i) um módulo de extrapolação, onde um tecido fresco é cortado para preparar amostra de tecido, (ii) um módulo de endurecimento que endurece a amostra de tecido, (iii) um módulo de impregnação que impregna a amostra de tecido que estava endurecida, e (iv) um módulo de incorporação que incorpora uma amostra de tecido que foi endurecida e impregnada. o tecido fresco , que foi retirado para o diagnóstico da doença, ou para avaliar o tratamento cirúrgico, é extrapolado para cerca de 0,6 mm. de preferência, o endurecimento do tecido fresco é iniciado, mas não completado, durante a extrapolação por meio do contato com uma mistura química. de preferência, gelo seco, dispositivo termoelétrico, ou condensador de gás resfria um molde de metal que contém a amostra incorporada. ele é seccionado e, em seguida, examinado microscopicamente como uma alternativa para o exame histológico de uma seção congelada para evitar os problemas conhecidos de diagnóstico discordante e diferido.
BR112014007683-9A 2011-09-29 2012-09-28 sistema e método para o processamento de uma amostra de um tecido sólido, módulo de extrapolação de tecido sólido e ferramenta de extrapolação BR112014007683B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161540947P 2011-09-29 2011-09-29
US61/540,947 2011-09-29
PCT/US2012/057907 WO2013049564A2 (en) 2011-09-29 2012-09-28 Ultra-rapid diagnostic tissue preparation as an alternative to frozen section

Publications (2)

Publication Number Publication Date
BR112014007683A2 true BR112014007683A2 (pt) 2017-04-18
BR112014007683B1 BR112014007683B1 (pt) 2021-02-09

Family

ID=47996762

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014007683-9A BR112014007683B1 (pt) 2011-09-29 2012-09-28 sistema e método para o processamento de uma amostra de um tecido sólido, módulo de extrapolação de tecido sólido e ferramenta de extrapolação

Country Status (8)

Country Link
US (1) US9217696B2 (pt)
EP (1) EP2761268A4 (pt)
JP (1) JP6189306B2 (pt)
CN (1) CN103975229B (pt)
AU (1) AU2012315744B2 (pt)
BR (1) BR112014007683B1 (pt)
CA (1) CA2849908C (pt)
WO (1) WO2013049564A2 (pt)

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EP3091916A1 (en) 2014-01-10 2016-11-16 Lifecell Corporation Vacuum platen tissue planing apparatus
US11353380B2 (en) * 2014-09-23 2022-06-07 Shabbir Bambot Apparatus for faster pathology
JP2017003504A (ja) * 2015-06-15 2017-01-05 ブレスト・ヘルスケア株式会社 生検サンプルの分割方法ならびに分割装置
CN105300757A (zh) * 2015-09-22 2016-02-03 王善宗 一种快速简易病理冷冻标本制片方法
KR101765460B1 (ko) * 2016-01-11 2017-08-07 주식회사 메딕슨 카트리지형 극초단파 생체시료 고정장치
US10537349B1 (en) 2016-02-08 2020-01-21 Lifecell Corporation Method for processing tissue to control thickness
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CN106501065A (zh) * 2016-10-20 2017-03-15 达科为（深圳）医疗设备有限公司 一种智能组织脱水系统
CN107179406A (zh) * 2017-05-27 2017-09-19 福州迈新生物技术开发有限公司 癌栓多标免疫组化染色试剂盒
CN107402213B (zh) * 2017-08-29 2023-09-22 苏州欧谱曼迪科技有限公司 探头、探头装置以及显微系统
CN110243640B (zh) * 2018-03-08 2022-01-25 中国科学院海洋研究所 深海有孔虫的内腔磨片快速制备方法
CN111989558A (zh) * 2018-03-16 2020-11-24 因为傲可值有限公司 用于自动处理组织学样品的样品处理系统和方法
KR102292634B1 (ko) * 2019-07-18 2021-08-23 (의)삼성의료재단 조직 검사용 샘플 제조 장치
WO2021026799A1 (zh) * 2019-08-14 2021-02-18 中国科学院深圳先进技术研究院 包埋模具及其使用方法
JP7405690B2 (ja) * 2020-05-18 2023-12-26 株式会社堀場テクノサービス 分析面切削用治具、分析装置、分析面切削方法、及び分析方法
CN113029640A (zh) * 2021-04-26 2021-06-25 吕然然 一种生物实验用冷冻式切片装置
CN113029728B (zh) * 2021-05-24 2021-09-10 北京恩泽康泰生物科技有限公司 一种使用冰冻切片机提高组织外泌体产量的方法
CN113567482A (zh) * 2021-07-16 2021-10-29 江南大学 一种监测蒸煮过程中谷物内部组分结构及分布的方法

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Also Published As

Publication number Publication date
AU2012315744B2 (en) 2015-09-24
JP2014528575A (ja) 2014-10-27
CA2849908C (en) 2019-03-05
EP2761268A4 (en) 2015-08-12
JP6189306B2 (ja) 2017-08-30
US20140234895A1 (en) 2014-08-21
WO2013049564A3 (en) 2013-05-23
CA2849908A1 (en) 2013-04-04
CN103975229A (zh) 2014-08-06
AU2012315744A1 (en) 2014-04-17
US9217696B2 (en) 2015-12-22
CN103975229B (zh) 2017-09-22
WO2013049564A2 (en) 2013-04-04
BR112014007683B1 (pt) 2021-02-09
EP2761268A2 (en) 2014-08-06

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/09/2012, OBSERVADAS AS CONDICOES LEGAIS.