BR112014001342A2 - Método de recuperação de um diácido a partir de um meio de fermentação - Google Patents
Método de recuperação de um diácido a partir de um meio de fermentaçãoInfo
- Publication number
- BR112014001342A2 BR112014001342A2 BR112014001342A BR112014001342A BR112014001342A2 BR 112014001342 A2 BR112014001342 A2 BR 112014001342A2 BR 112014001342 A BR112014001342 A BR 112014001342A BR 112014001342 A BR112014001342 A BR 112014001342A BR 112014001342 A2 BR112014001342 A2 BR 112014001342A2
- Authority
- BR
- Brazil
- Prior art keywords
- diacids
- salts
- divalent metal
- ammonium salts
- pressure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
- C07C51/493—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification whereby carboxylic acid esters are formed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
- C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
MÉTODO DE RECUPERAÇÃO DE UM DIÁCIDO ORGÂNICO A PARTIR DE UM MEIO DE FERMENTAÇÃO. São revelados métodos para a formação de sais de amônio de diácidos C4 em um processo de fermentação com remoção de sais metálicos bivalentes carbonato. O pH dos caldos de fermentação para produção de diácidos C4 é controlado pela adição de oxigênio alcalino contendo compostos de cálcio ou magnésio, o que forma sais metálicos bivalentes dos diácidos. Os sais metálicos bivalentes dos diácidos são substituídos por amônio pela introdução de sais de amônio em temperatura e pressão elevadas formando sais solúveis de amônio destes. CO2 ou bicarbonato é simultaneamente adicionado aos meios de fermentação em temperatura e pressão elevadas. Reduzindo-se a temperatura e a pressão, formam-se sais metálicos bivalentes de carbonato insolúveis que são separados dos sais de amônio de diácidos solubilizados. Os sais de carbonato recuperados podem ser reciclados como materiais de controle de pH em fermentações subsequentes. Os sais de amônio de diácidos solubilizados podem formar os derivados N-metil-2-pirrolidona (NMP), gama-butirolactona (GBL) e 1,4-butona-diol (BDO) em reações em recipiente único.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161510204P | 2011-07-21 | 2011-07-21 | |
US201161510209P | 2011-07-21 | 2011-07-21 | |
PCT/US2012/045933 WO2013012589A1 (en) | 2011-07-21 | 2012-07-09 | Methods for preparation of ammonium salts of c4 diacids by fermentation and integrated methods for making c4 derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014001342A2 true BR112014001342A2 (pt) | 2017-10-03 |
Family
ID=47558393
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014001382-9A BR112014001382B1 (pt) | 2011-07-21 | 2012-07-09 | método de produção de composto derivado do ácido c4 |
BR112014001342A BR112014001342A2 (pt) | 2011-07-21 | 2012-07-09 | Método de recuperação de um diácido a partir de um meio de fermentação |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014001382-9A BR112014001382B1 (pt) | 2011-07-21 | 2012-07-09 | método de produção de composto derivado do ácido c4 |
Country Status (8)
Country | Link |
---|---|
US (3) | US20140162326A1 (pt) |
EP (2) | EP2734509B1 (pt) |
CN (2) | CN103827308B (pt) |
BR (2) | BR112014001382B1 (pt) |
ES (1) | ES2717873T3 (pt) |
MX (2) | MX360202B (pt) |
TR (1) | TR201904063T4 (pt) |
WO (2) | WO2013012590A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130072714A1 (en) * | 2011-09-16 | 2013-03-21 | BioAmber International S.à.r.l. | Biobased compositions of diammonium succinate, monoammonium succinate and/or succinic acid and derivatives thereof |
US10787686B2 (en) * | 2015-10-28 | 2020-09-29 | Kao Corporation | Method for producing C4-dicarboxylic acid |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2816923A (en) * | 1956-03-13 | 1957-12-17 | California Research Corp | Conversion of maleic acid to fumaric acid |
US3117991A (en) * | 1960-07-29 | 1964-01-14 | Halcon International Inc | Preparation of fumaric acid by heating malic acid with maleic anhydride |
US3113138A (en) * | 1961-12-20 | 1963-12-03 | Fmc Corp | Preparation of butyrolactone |
US3923597A (en) * | 1974-08-01 | 1975-12-02 | Gen Electric | Mercury concentration by the use of microorganisms |
US4059513A (en) * | 1975-08-04 | 1977-11-22 | Zadera Karel V | Treatment of water to remove certain ions therefrom |
US4048013A (en) * | 1976-06-10 | 1977-09-13 | Gesellschaft Fur Molekularbiologische Forschung Mbh | Process for producing single-cell protein from methanol using methylomonas sp. DSM 580 |
US5008468A (en) * | 1986-04-16 | 1991-04-16 | Catalytica, Inc. | Acid catalyzed process |
GB8707595D0 (en) * | 1987-03-31 | 1987-05-07 | British Petroleum Co Plc | Chemical process |
DE4018242A1 (de) * | 1990-06-07 | 1991-12-12 | Basf Ag | Verfahren zur herstellung von n-substituierten pyrrolidonen |
US5766439A (en) * | 1996-10-10 | 1998-06-16 | A. E. Staley Manufacturing Co. | Production and recovery of organic acids |
US5969164A (en) * | 1996-12-20 | 1999-10-19 | The Standard Oil Company | Catalysts for the hydrogenation of maleic acid to 1,4-butanediol |
US6071728A (en) * | 1997-01-09 | 2000-06-06 | Amylum Belgium, N.V. | Process for the production of crystalline aspartic acid |
US5958744A (en) * | 1997-08-18 | 1999-09-28 | Applied Carbochemicals | Succinic acid production and purification |
US6603021B2 (en) * | 2001-06-18 | 2003-08-05 | Battelle Memorial Institute | Methods of making pyrrolidones |
US7199250B2 (en) * | 2002-12-20 | 2007-04-03 | Battelle Memorial Institute | Process for producing cyclic compounds |
WO2005045049A1 (ja) * | 2003-11-07 | 2005-05-19 | Mitsubishi Chemical Corporation | 有機酸アンモニウム溶液の製造方法 |
CN1878868A (zh) * | 2003-11-07 | 2006-12-13 | 三菱化学株式会社 | 制造有机酸铵溶液的方法 |
JP2005295998A (ja) * | 2003-11-07 | 2005-10-27 | Mitsubishi Chemicals Corp | 有機酸アンモニウム溶液の製造方法 |
ES2396139T3 (es) * | 2004-12-21 | 2013-02-19 | Basf Se | Método para la producción de pirrolidonas a partir de succinatos de caldos de fermentación |
JP5333213B2 (ja) * | 2007-05-18 | 2013-11-06 | 味の素株式会社 | コハク酸およびコハク酸アンモニウム溶液の製造方法 |
CN102317432B (zh) * | 2007-08-17 | 2015-11-25 | 巴斯夫欧洲公司 | 巴斯德氏菌科(Pasteurellaceae)的羧酸产生成员 |
EP2215213B1 (en) * | 2007-11-01 | 2013-05-08 | Oberon Fmr, Inc. | Biosolids-based food additive for animal feed and methods of production |
CA2625511A1 (en) * | 2008-03-13 | 2009-09-13 | Dilum Dunuwila | Process for the direct production of esters of carboxylic acids from fermentation broths |
FR2933978B1 (fr) * | 2008-07-18 | 2012-12-21 | Arkema France | Fabrication d'anhydride maleique a partir de matieres renouvelables, anhydride maleique obtenu et utilisations |
BRPI0922836B1 (pt) * | 2008-12-02 | 2018-09-25 | Purac Biochem Bv | processo para a preparação de um sal de succinato monovalente |
CN101475477A (zh) * | 2009-01-23 | 2009-07-08 | 上海化学试剂研究所 | 反丁烯二酸二甲酯的制备方法 |
EP2396401B1 (en) * | 2009-02-16 | 2018-12-19 | Basf Se | Novel microbial succinic acid producers and purification of succinic acid |
US8431372B2 (en) | 2009-06-19 | 2013-04-30 | Mbi International | Fermentation method using a magnesium compound containing oxygen |
CN102482693A (zh) * | 2009-07-01 | 2012-05-30 | 诺维信北美公司 | 用于分离和回收c4二羧酸的工艺 |
US8624059B2 (en) * | 2010-03-26 | 2014-01-07 | Bioamber S.A.S. | Processes for producing monoammonium succinate from fermentation broths containing diammonium succinate, monoammonium succinate and/or succinic acid, and conversion of monoammonium succinate to succinic acid |
US8410291B2 (en) * | 2010-04-01 | 2013-04-02 | BioAmber International S.á.r.l. | Processes for the production of hydrogenated products |
KR20130020779A (ko) * | 2010-04-01 | 2013-02-28 | 바이오엠버 인터내셔널 에스.에이.알.엘. | 숙신산염으로부터 테트라하이드로퓨란, 감마-부티로락톤 및/또는 부탄디올의 제조방법 |
US8399687B2 (en) * | 2010-04-01 | 2013-03-19 | Bioamber International S.A.R.L. | Processes for the production of hydrogenated products |
KR20130041815A (ko) * | 2010-05-19 | 2013-04-25 | 바이오엠버, 에스.아.에스. | 피롤리돈의 제조방법 |
JP2013528604A (ja) * | 2010-05-19 | 2013-07-11 | ビオアンブ,ソシエテ パ アクシオンス シンプリフィエ | ピロリドンの製造方法 |
-
2012
- 2012-07-09 BR BR112014001382-9A patent/BR112014001382B1/pt active IP Right Grant
- 2012-07-09 MX MX2014000838A patent/MX360202B/es active IP Right Grant
- 2012-07-09 TR TR2019/04063T patent/TR201904063T4/tr unknown
- 2012-07-09 EP EP12815444.0A patent/EP2734509B1/en active Active
- 2012-07-09 CN CN201280045504.4A patent/CN103827308B/zh active Active
- 2012-07-09 BR BR112014001342A patent/BR112014001342A2/pt not_active Application Discontinuation
- 2012-07-09 WO PCT/US2012/045937 patent/WO2013012590A1/en active Application Filing
- 2012-07-09 CN CN201280044534.3A patent/CN103797003B/zh active Active
- 2012-07-09 US US14/233,285 patent/US20140162326A1/en not_active Abandoned
- 2012-07-09 EP EP12814623.0A patent/EP2734629A4/en not_active Withdrawn
- 2012-07-09 WO PCT/US2012/045933 patent/WO2013012589A1/en active Application Filing
- 2012-07-09 ES ES12815444T patent/ES2717873T3/es active Active
- 2012-07-09 US US14/233,282 patent/US20140127767A1/en not_active Abandoned
- 2012-07-09 MX MX2014000839A patent/MX2014000839A/es unknown
-
2016
- 2016-09-28 US US15/278,649 patent/US20170029353A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TR201904063T4 (tr) | 2019-04-22 |
EP2734629A4 (en) | 2015-02-25 |
CN103827308A (zh) | 2014-05-28 |
US20140127767A1 (en) | 2014-05-08 |
BR112014001382A2 (pt) | 2017-04-25 |
MX360202B (es) | 2018-10-25 |
EP2734509A1 (en) | 2014-05-28 |
BR112014001382B1 (pt) | 2020-11-10 |
US20170029353A1 (en) | 2017-02-02 |
EP2734509B1 (en) | 2018-12-26 |
WO2013012589A1 (en) | 2013-01-24 |
EP2734629A1 (en) | 2014-05-28 |
CN103827308B (zh) | 2016-08-24 |
WO2013012590A1 (en) | 2013-01-24 |
ES2717873T3 (es) | 2019-06-26 |
CN103797003B (zh) | 2016-10-26 |
CN103797003A (zh) | 2014-05-14 |
MX2014000838A (es) | 2015-04-08 |
MX2014000839A (es) | 2014-09-22 |
EP2734509A4 (en) | 2015-03-04 |
US20140162326A1 (en) | 2014-06-12 |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |