BR112013020456A2 - nova composição antifúngica - Google Patents
nova composição antifúngicaInfo
- Publication number
- BR112013020456A2 BR112013020456A2 BR112013020456A BR112013020456A BR112013020456A2 BR 112013020456 A2 BR112013020456 A2 BR 112013020456A2 BR 112013020456 A BR112013020456 A BR 112013020456A BR 112013020456 A BR112013020456 A BR 112013020456A BR 112013020456 A2 BR112013020456 A2 BR 112013020456A2
- Authority
- BR
- Brazil
- Prior art keywords
- antifungal composition
- new antifungal
- pharmaceutical composition
- present
- diol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
nova composição antifúngica a presente invenção está correlacionada a uma composição farmacêutica para o tratamento de infecção na unha causada por fungo, compreendendo um composto antifúngico de alilamina presente em uma quantidade de cerca de 10%, um ácido orgânico ou um éster do mesmo, um diol e um agente sequëstrador, e em que a composição farmacológica é substancialmente isenta de água.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1150107 | 2011-02-11 | ||
PCT/EP2012/052327 WO2012107565A1 (en) | 2011-02-11 | 2012-02-10 | Novel antifungal composition |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013020456A2 true BR112013020456A2 (pt) | 2016-10-18 |
BR112013020456B1 BR112013020456B1 (pt) | 2020-01-21 |
Family
ID=45581892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013020456A BR112013020456B1 (pt) | 2011-02-11 | 2012-02-10 | nova composição antifúngica |
Country Status (25)
Country | Link |
---|---|
US (3) | US8952070B2 (pt) |
EP (1) | EP2672962B1 (pt) |
JP (1) | JP5883886B2 (pt) |
KR (1) | KR101647545B1 (pt) |
CN (2) | CN109453150A (pt) |
AU (1) | AU2012215383B2 (pt) |
BR (1) | BR112013020456B1 (pt) |
CA (1) | CA2826741C (pt) |
CY (1) | CY1116275T1 (pt) |
DK (1) | DK2672962T3 (pt) |
ES (1) | ES2535827T3 (pt) |
HK (1) | HK1190944A1 (pt) |
HR (1) | HRP20150507T1 (pt) |
IL (1) | IL227765A (pt) |
ME (1) | ME02152B (pt) |
MX (1) | MX335945B (pt) |
PL (1) | PL2672962T3 (pt) |
PT (1) | PT2672962E (pt) |
RS (1) | RS53982B1 (pt) |
RU (1) | RU2587064C2 (pt) |
SG (1) | SG192615A1 (pt) |
SI (1) | SI2672962T1 (pt) |
SM (1) | SMT201500154B (pt) |
WO (1) | WO2012107565A1 (pt) |
ZA (1) | ZA201305891B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2672962B1 (en) | 2011-02-11 | 2015-03-25 | Moberg Pharma AB | Novel antifungal composition |
JP5815879B2 (ja) | 2012-08-30 | 2015-11-17 | ▲華▼▲為▼終端有限公司Huawei Device Co., Ltd. | 中央処理装置を制御する方法および装置 |
KR20180070607A (ko) * | 2015-10-07 | 2018-06-26 | 엑소도스 라이프 사이언시스 엘피 | 항진균 국소 조성물 |
US10251858B1 (en) | 2016-08-08 | 2019-04-09 | Marlinz Pharma, LLC | Composition for treating fungal infections in nails |
US10543276B2 (en) | 2016-08-08 | 2020-01-28 | Marlinz Pharma, LLC | Topical compositions |
EP3292758A1 (en) | 2016-09-07 | 2018-03-14 | Rottapharm S.p.A. | Antimicrobial composition comprising a carboxylic acid and two diols |
WO2019206389A1 (en) * | 2018-04-27 | 2019-10-31 | Unigroup Aps | Kit of parts for nail fungus |
US11576920B2 (en) | 2019-03-18 | 2023-02-14 | The Menopause Method, Inc. | Composition and method to aid in hormone replacement therapy |
IL303476A (en) | 2020-12-08 | 2023-08-01 | Moberg Pharma Ab | Nail fungus treatment regimen using allylamine antifungal preparations |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525635A (en) | 1986-02-04 | 1996-06-11 | Moberg; Sven | Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof |
DE4337945A1 (de) * | 1993-11-06 | 1995-05-11 | Labtec Gmbh | Pflaster zur Behandlung von Nagelmykosen |
US6165484A (en) | 1997-08-26 | 2000-12-26 | Wake Forest University | EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections |
AUPP146598A0 (en) * | 1998-01-21 | 1998-02-12 | Health And Hygiene International Pty Ltd | Fruit and vegetable wash |
DE19921794A1 (de) | 1999-05-11 | 2000-11-23 | Hexal Ag | Neue pharmazeutische Zusammensetzung |
US7074392B1 (en) | 2000-03-27 | 2006-07-11 | Taro Pharmaceutical Industries Limited | Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections |
JP4803511B2 (ja) * | 2000-08-25 | 2011-10-26 | 株式会社ポーラファルマ | 抗真菌医薬組成物 |
CN1678277B (zh) * | 2002-07-29 | 2010-05-05 | 艾克里麦德公司 | 治疗皮肤病的方法和组合物 |
CA2492976C (en) * | 2002-09-05 | 2011-11-01 | Galderma Research & Development, S.N.C. | Solution for ungual and peri-ungual application |
JP5059408B2 (ja) * | 2004-08-05 | 2012-10-24 | 久光製薬株式会社 | 爪用外用剤 |
US20060078599A1 (en) * | 2004-10-12 | 2006-04-13 | Mathew Ebmeier | Pharmaceutical composition applicable to body tissue |
JP4992181B2 (ja) | 2004-12-28 | 2012-08-08 | 大正製薬株式会社 | 外用剤組成物 |
WO2006103638A2 (en) | 2005-03-31 | 2006-10-05 | Ranbaxy Laboratories Limited | Topical pharmaceutical compositions of terbinafine and processes for their preparation |
GB0511499D0 (en) * | 2005-06-06 | 2005-07-13 | Medpharm Ltd | Topical ungual formulations |
CN1939539A (zh) | 2005-09-29 | 2007-04-04 | 瑞士商拜欧伊果公司 | 疣、指甲疾病、及指甲保养用之局部配方 |
CA2640889A1 (en) * | 2006-01-02 | 2007-07-12 | Tlt Medical Ltd. | Pharmaceutical composition for the treatment of nail diseases |
WO2007106622A2 (en) * | 2006-02-03 | 2007-09-20 | Carl Lawyer | Fungicidal formulation and method of use |
WO2007094999A2 (en) * | 2006-02-13 | 2007-08-23 | Stiefel Laboratories, Inc. | Ungual antifungal compositions |
US20080038219A1 (en) | 2006-08-07 | 2008-02-14 | Calgenex Corporation | Novel Composition for a Topical Skin Treatment Base and Medicated Applications Thereof |
WO2008152444A2 (en) * | 2006-11-29 | 2008-12-18 | Foamix Ltd. | Foamable waterless compositions with modulating agents |
WO2008097530A1 (en) | 2007-02-05 | 2008-08-14 | Biophile Corporation, Ltd | Increased effectiveness of allylamine drug compounds |
US20080261986A1 (en) * | 2007-03-30 | 2008-10-23 | Friden Phillip M | Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug |
WO2009140215A2 (en) | 2008-05-11 | 2009-11-19 | Geraghty, Erin | Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds |
WO2010010470A2 (en) * | 2008-07-23 | 2010-01-28 | Tdt, Ltd | Methods of administering topical antifungal formulations for the treatment of fungal infections |
US8524258B2 (en) * | 2008-12-22 | 2013-09-03 | Johnson & Johnson Consumer Companies, Inc. | Structured lotions |
FR2942716B1 (fr) * | 2009-03-06 | 2011-04-15 | Galderma Res & Dev | Methode de solubilisation d'agent antifongique et compositions a haute concentration en agent antifongique applicables sur l'ongle |
BR112012003209A2 (pt) | 2009-08-13 | 2016-03-01 | Moberg Derma Ab | composições e métodos para tratar infecção fúngica da unha |
WO2011079234A2 (en) | 2009-12-23 | 2011-06-30 | Nuvo Research Inc. | Highly permeating terbinafine formulation |
WO2012017371A1 (en) | 2010-08-02 | 2012-02-09 | Sulur Subramaniam Vanangamudi | A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, clobetasole propionate, terbinafine hydrochloride and a process to make it |
EP2672962B1 (en) | 2011-02-11 | 2015-03-25 | Moberg Pharma AB | Novel antifungal composition |
-
2012
- 2012-02-10 EP EP12703537.6A patent/EP2672962B1/en active Active
- 2012-02-10 KR KR1020137023067A patent/KR101647545B1/ko active IP Right Grant
- 2012-02-10 JP JP2013552973A patent/JP5883886B2/ja active Active
- 2012-02-10 CA CA2826741A patent/CA2826741C/en active Active
- 2012-02-10 WO PCT/EP2012/052327 patent/WO2012107565A1/en active Application Filing
- 2012-02-10 MX MX2013009245A patent/MX335945B/es unknown
- 2012-02-10 BR BR112013020456A patent/BR112013020456B1/pt active IP Right Grant
- 2012-02-10 RU RU2013136147/15A patent/RU2587064C2/ru active
- 2012-02-10 US US13/984,657 patent/US8952070B2/en active Active
- 2012-02-10 ME MEP-2015-70A patent/ME02152B/me unknown
- 2012-02-10 RS RS20150300A patent/RS53982B1/en unknown
- 2012-02-10 AU AU2012215383A patent/AU2012215383B2/en active Active
- 2012-02-10 SG SG2013059274A patent/SG192615A1/en unknown
- 2012-02-10 ES ES12703537.6T patent/ES2535827T3/es active Active
- 2012-02-10 SI SI201230198T patent/SI2672962T1/sl unknown
- 2012-02-10 PL PL12703537T patent/PL2672962T3/pl unknown
- 2012-02-10 CN CN201811087157.7A patent/CN109453150A/zh active Pending
- 2012-02-10 DK DK12703537T patent/DK2672962T3/en active
- 2012-02-10 PT PT127035376T patent/PT2672962E/pt unknown
- 2012-02-10 CN CN201280007874.9A patent/CN103384518B/zh active Active
-
2013
- 2013-08-01 IL IL227765A patent/IL227765A/en active IP Right Grant
- 2013-08-06 ZA ZA2013/05891A patent/ZA201305891B/en unknown
-
2014
- 2014-05-05 HK HK14104270.7A patent/HK1190944A1/xx unknown
- 2014-11-06 US US14/534,640 patent/US9561279B2/en active Active
-
2015
- 2015-05-13 CY CY20151100425T patent/CY1116275T1/el unknown
- 2015-05-13 HR HRP20150507TT patent/HRP20150507T1/hr unknown
- 2015-06-30 SM SM201500154T patent/SMT201500154B/xx unknown
-
2016
- 2016-12-20 US US15/384,536 patent/US20170258914A1/en not_active Abandoned
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Legal Events
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/02/2012, OBSERVADAS AS CONDICOES LEGAIS. |