ME02152B - Nove antigljivične kompozicije - Google Patents

Nove antigljivične kompozicije

Info

Publication number
ME02152B
ME02152B MEP-2015-70A MEP201570A ME02152B ME 02152 B ME02152 B ME 02152B ME P201570 A MEP201570 A ME P201570A ME 02152 B ME02152 B ME 02152B
Authority
ME
Montenegro
Prior art keywords
preparation according
amount
acid
diol
allylamine
Prior art date
Application number
MEP-2015-70A
Other languages
English (en)
Inventor
Ake Lindahl
Original Assignee
Moberg Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45581892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME02152(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Moberg Pharma Ab filed Critical Moberg Pharma Ab
Publication of ME02152B publication Critical patent/ME02152B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (13)

1. Farmaceutski preparat za tretman gljivične infekcije nokta koji sadrži alilaminsko jedinjenje kao antimikotik u količini većoj od 5%, kao i organsku kiselinu ili estar, diol i dodatni sredstvo, pri čemu dodatno sredstvo označava aminosirećnu kiselinu, a navedeni farmaceutski preparat je suštinski bez vode.
2. Preparat prema patentnom zahtjevu 1, naznačen time, što je antigljivično alilaminsko jedinjenje rastvoreno u preparatu.
3. Preparat prema patentnim zahtjevima 1 ili 2, naznačen time, što organska kiselina označava mlječnu kiselinu.
4. Preparat prema bilo kom od zahtjeva od 1 do 3, naznačen time, što su organska kiselina ili njen estar prisutni u količini od 5% do 25%.
5. Preparat prema bilo kom od zahteva od 1 do 4, naznačen time, što diol označava diol izabran iz grupe koju čine propandiol, butandiol, pentandiol i heksandiol.
6. Preparat prema bilo kom od zahtjeva od 1 do 5, naznačen time, što je diol prisutan u količini većoj od 50%.
7. Preparat prema bilo kom od zahtjeva od 1 do 6, naznačen time, što alilaminsko antigljivično jedinjenje označava terbinafin.
8. Preparat prema bilo kom od prethodnih patentnih zahtjeva, naznačen time, što je alilaminsko antigljivično jedinjenje prisutno u količini od 5% do 12%.
9. Preparat prema patentnom zahtevu 8, naznačen time, što je alilaminsko antigljivično jedinjenje prisutno u količini od 8% do 11,5%.
10. Preparat prema bilo kom od prethodnih patentnih zahtjeva, naznačen time, što aminosirćetna kiselina označava etilendiamintetrasirćetnu kiselinu (EDTA).
11. Preparat prema patentnom zahtjevu 1 ili 2, naznačen time, što sadrži mlječnu kiselinu u količini od 5% do 25%; diol izabran iz grupe koju čine propandiol, butandiol, pentandiol i heksandiol u količini većoj od 50%; terbinafin u količini od 5% do 12%; i EDTA u količini između 0,03% i 1%.
12. Preparat prema patentnom zahtjevu 1 ili 2, naznačen time, što sadrži od oko 67.5% do oko 84% propandiola, od 8% do 20% mlečne kiseline, od 0.03% do 0,1% EDTA i od 8% do 12% od terbinafina.
13. Farmaceutski preparat prema bilo kom od zahtjeva od 1 do 12 za upotrebu u postupku tretmana gljivične infekcije nokta.
MEP-2015-70A 2011-02-11 2012-02-10 Nove antigljivične kompozicije ME02152B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1150107 2011-02-11
EP12703537.6A EP2672962B1 (en) 2011-02-11 2012-02-10 Novel antifungal composition
PCT/EP2012/052327 WO2012107565A1 (en) 2011-02-11 2012-02-10 Novel antifungal composition

Publications (1)

Publication Number Publication Date
ME02152B true ME02152B (me) 2015-10-20

Family

ID=45581892

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2015-70A ME02152B (me) 2011-02-11 2012-02-10 Nove antigljivične kompozicije

Country Status (24)

Country Link
US (3) US8952070B2 (me)
EP (1) EP2672962B1 (me)
JP (1) JP5883886B2 (me)
KR (1) KR101647545B1 (me)
CN (2) CN103384518B (me)
AU (1) AU2012215383B2 (me)
BR (1) BR112013020456B1 (me)
CA (1) CA2826741C (me)
CY (1) CY1116275T1 (me)
DK (1) DK2672962T3 (me)
ES (1) ES2535827T3 (me)
HR (1) HRP20150507T1 (me)
IL (1) IL227765A (me)
ME (1) ME02152B (me)
MX (1) MX335945B (me)
PL (1) PL2672962T3 (me)
PT (1) PT2672962E (me)
RS (1) RS53982B1 (me)
RU (1) RU2587064C2 (me)
SG (1) SG192615A1 (me)
SI (1) SI2672962T1 (me)
SM (1) SMT201500154B (me)
WO (1) WO2012107565A1 (me)
ZA (1) ZA201305891B (me)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2672962T3 (en) 2011-02-11 2015-04-20 Moberg Pharma Ab Novel anti-fungal composition
EP3151085B1 (en) * 2012-08-30 2018-07-11 Huawei Device (Dongguan) Co., Ltd. Method, apparatus and computer program product for controlling central processing unit
US10272054B2 (en) * 2015-10-07 2019-04-30 Exodos Life Sciences Lp Topical antifungal compositions
US10543276B2 (en) 2016-08-08 2020-01-28 Marlinz Pharma, LLC Topical compositions
US10206962B1 (en) 2016-08-08 2019-02-19 Marlinz Pharma, LLC Method for treating fungal infections in nails
EP3292758A1 (en) 2016-09-07 2018-03-14 Rottapharm S.p.A. Antimicrobial composition comprising a carboxylic acid and two diols
WO2019206389A1 (en) * 2018-04-27 2019-10-31 Unigroup Aps Kit of parts for nail fungus
US11576920B2 (en) 2019-03-18 2023-02-14 The Menopause Method, Inc. Composition and method to aid in hormone replacement therapy
IL303476A (en) 2020-12-08 2023-08-01 Moberg Pharma Ab Treatment regimen for onychomycosis using allylamine antifungal compositions

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Also Published As

Publication number Publication date
HRP20150507T1 (hr) 2015-06-19
AU2012215383A1 (en) 2013-08-29
JP5883886B2 (ja) 2016-03-15
CN109453150A (zh) 2019-03-12
ES2535827T3 (es) 2015-05-18
AU2012215383B2 (en) 2016-06-09
KR20140025341A (ko) 2014-03-04
MX2013009245A (es) 2013-12-09
CY1116275T1 (el) 2017-02-08
DK2672962T3 (en) 2015-04-20
PT2672962E (pt) 2015-05-25
CN103384518A (zh) 2013-11-06
BR112013020456B1 (pt) 2020-01-21
RU2587064C2 (ru) 2016-06-10
WO2012107565A1 (en) 2012-08-16
KR101647545B1 (ko) 2016-08-10
US20140031430A1 (en) 2014-01-30
RS53982B1 (sr) 2015-10-30
IL227765A (en) 2016-09-29
CN103384518B (zh) 2018-10-26
CA2826741A1 (en) 2012-08-16
SI2672962T1 (sl) 2015-06-30
EP2672962B1 (en) 2015-03-25
SG192615A1 (en) 2013-09-30
PL2672962T3 (pl) 2015-08-31
US20150250878A1 (en) 2015-09-10
EP2672962A1 (en) 2013-12-18
US9561279B2 (en) 2017-02-07
US20170258914A1 (en) 2017-09-14
SMT201500154B (it) 2015-09-07
US8952070B2 (en) 2015-02-10
ZA201305891B (en) 2015-06-24
HK1190944A1 (en) 2014-07-18
RU2013136147A (ru) 2015-03-20
BR112013020456A2 (pt) 2016-10-18
MX335945B (es) 2016-01-04
CA2826741C (en) 2016-03-29
JP2014508146A (ja) 2014-04-03
IL227765A0 (en) 2013-09-30

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