BR112013020216A2 - Processo para produzir substância-alvo através do processo de fermentação - Google Patents

Processo para produzir substância-alvo através do processo de fermentação

Info

Publication number
BR112013020216A2
BR112013020216A2 BR112013020216A BR112013020216A BR112013020216A2 BR 112013020216 A2 BR112013020216 A2 BR 112013020216A2 BR 112013020216 A BR112013020216 A BR 112013020216A BR 112013020216 A BR112013020216 A BR 112013020216A BR 112013020216 A2 BR112013020216 A2 BR 112013020216A2
Authority
BR
Brazil
Prior art keywords
target substance
producing target
fermentation process
culture
fermentation
Prior art date
Application number
BR112013020216A
Other languages
English (en)
Other versions
BR112013020216B1 (pt
Inventor
Ujihara Tetsuro
Abe Tetsuya
Yagasaki Makoto
Original Assignee
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Publication of BR112013020216A2 publication Critical patent/BR112013020216A2/pt
Publication of BR112013020216B1 publication Critical patent/BR112013020216B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01069—Protein-Npi-phosphohistidine-sugar phosphotransferase (2.7.1.69), i.e. sucrose phosphotransferase system II
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/03—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
    • C12Y207/03009—Phosphoenolpyruvate-protein phosphotransferase (2.7.3.9)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCESSO PARA PRODUZIR SUBSTÂNCIA-ALVO ATRAVÉS DO PROCESSO DE FERMENTAÇÃO. A presente invenção refere-se à substância-alvo, que pode ser eficientemente produzida culturando, em um meio, uma bactéria corineforme em que a atividade de uma proteína PTS relacionada à absorção de frutose é reduzida ou perdida quando comparada com a cepa de origem, e a bactéria pode produzir a substância-alvo, possibilitando a substância-alvo se formar e se acumular em uma cultura; e coletando a substância-alvo da cultura
BR112013020216-5A 2011-02-09 2012-02-09 processo para produzir substância-alvo através do processo defermentação BR112013020216B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011025750 2011-02-09
JP2011-025750 2011-02-09
PCT/JP2012/052947 WO2012108493A1 (ja) 2011-02-09 2012-02-09 発酵法による目的物質の製造法

Publications (2)

Publication Number Publication Date
BR112013020216A2 true BR112013020216A2 (pt) 2017-08-29
BR112013020216B1 BR112013020216B1 (pt) 2020-12-01

Family

ID=46638705

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013020216-5A BR112013020216B1 (pt) 2011-02-09 2012-02-09 processo para produzir substância-alvo através do processo defermentação

Country Status (7)

Country Link
US (1) US9567616B2 (pt)
EP (1) EP2674499B1 (pt)
JP (2) JP6301581B2 (pt)
CN (1) CN103384723B (pt)
BR (1) BR112013020216B1 (pt)
ES (1) ES2790661T3 (pt)
WO (1) WO2012108493A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6857041B2 (ja) * 2017-02-01 2021-04-14 三谷産業株式会社 カルノシン製造方法及び新規微生物
USD854650S1 (en) 2017-09-15 2019-07-23 Briggs & Stratton Corporation Oil filter
CN109402033A (zh) * 2017-10-31 2019-03-01 天津科技大学 一种高效利用葡萄糖的类球红细菌工程菌及其构建方法
KR101999454B1 (ko) * 2017-12-19 2019-07-11 씨제이제일제당 (주) L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌 생산방법
CN109852572B (zh) * 2019-01-28 2021-05-28 江南大学 一种敲除大肠杆菌pts系统提高l-苏氨酸产量的方法
BR112023023070A2 (pt) * 2021-05-06 2024-01-30 Ajinomoto Kk Aparelho e método para controlar fermentação, e, método para fabricar uma substância objetiva por fermentação

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5618596A (en) 1979-07-23 1981-02-21 Ajinomoto Co Inc Production of l-lysine through fermentation process
JPS56144092A (en) 1980-04-14 1981-11-10 Ajinomoto Co Inc Preparation of l-methionine by fermentation
DE3127361A1 (de) 1981-07-08 1983-02-03 Schering Ag, 1000 Berlin Und 4619 Bergkamen Herstellung und anwendung von plasmiden mit genen fuer die biosynthese von l-prolin
JPS6394985A (ja) 1986-10-09 1988-04-26 Kyowa Hakko Kogyo Co Ltd Ｌ−チロシンの製造法
JP2779079B2 (ja) 1991-08-27 1998-07-23 キッコーマン株式会社 ペントースの選択発酵方法
DE19539952A1 (de) 1995-10-26 1997-04-30 Consortium Elektrochem Ind Verfahren zur Herstellung von O-Acetylserin, L-Cystein und L-Cystein-verwandten Produkten
DE19949579C1 (de) 1999-10-14 2000-11-16 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von L-Cystein oder L-Cystein-Derivaten
DE10112992A1 (de) * 2001-03-17 2002-09-26 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE60230040D1 (de) 2001-07-06 2009-01-08 Evonik Degussa Gmbh Fermentationsverfahren zur herstellung von l-aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae
RU2230114C2 (ru) 2001-11-30 2004-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот
US20050079617A1 (en) * 2003-10-03 2005-04-14 Cervin Marguerite A. Glucose transport mutants for production of biomaterial
CN101065477B (zh) 2004-06-25 2011-10-05 协和发酵生化株式会社 物质的制备方法
EP1801206B1 (en) 2004-09-28 2010-03-24 Kyowa Hakko Bio Co., Ltd. Method for producing l-arginine, l-ornithine or l-citrulline
CN101115832A (zh) * 2004-11-26 2008-01-30 协和发酵工业株式会社 工业上有用的微生物
EP2201126A4 (en) * 2007-09-26 2012-05-09 Archer Daniels Midland Co PRODUCTION OF AMINO ACIDS FROM SUCROSE IN <I> CORYNEBACTERIUM GLUTAMICUM </ I>
JP5833311B2 (ja) 2008-09-01 2015-12-16 国立大学法人信州大学 有用物質の製造法

Also Published As

Publication number Publication date
EP2674499A1 (en) 2013-12-18
US9567616B2 (en) 2017-02-14
CN103384723A (zh) 2013-11-06
ES2790661T3 (es) 2020-10-28
EP2674499A4 (en) 2015-10-28
EP2674499B1 (en) 2020-04-01
CN103384723B (zh) 2020-08-14
JPWO2012108493A1 (ja) 2014-07-03
JP2017023147A (ja) 2017-02-02
WO2012108493A1 (ja) 2012-08-16
US20130323784A1 (en) 2013-12-05
BR112013020216B1 (pt) 2020-12-01
JP6301581B2 (ja) 2018-03-28

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/02/2012, OBSERVADAS AS CONDICOES LEGAIS.