BR112013017629A2 - laminina-521 recombinante - Google Patents
laminina-521 recombinanteInfo
- Publication number
- BR112013017629A2 BR112013017629A2 BR112013017629A BR112013017629A BR112013017629A2 BR 112013017629 A2 BR112013017629 A2 BR 112013017629A2 BR 112013017629 A BR112013017629 A BR 112013017629A BR 112013017629 A BR112013017629 A BR 112013017629A BR 112013017629 A2 BR112013017629 A2 BR 112013017629A2
- Authority
- BR
- Brazil
- Prior art keywords
- recombinant laminin
- laminin
- recombinant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061424273P | 2010-12-17 | 2010-12-17 | |
| US201161488353P | 2011-05-20 | 2011-05-20 | |
| US201161533063P | 2011-09-09 | 2011-09-09 | |
| US201161537940P | 2011-09-22 | 2011-09-22 | |
| US201161565380P | 2011-11-30 | 2011-11-30 | |
| US201161565849P | 2011-12-01 | 2011-12-01 | |
| PCT/IB2011/003258 WO2012080842A1 (en) | 2010-12-17 | 2011-12-16 | Recombinant laminin-521 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013017629A2 true BR112013017629A2 (pt) | 2017-04-18 |
Family
ID=45755415
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013017629A BR112013017629A2 (pt) | 2010-12-17 | 2011-12-16 | laminina-521 recombinante |
| BR112013017632A BR112013017632A2 (pt) | 2010-12-17 | 2011-12-16 | meio de cultura celular |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013017632A BR112013017632A2 (pt) | 2010-12-17 | 2011-12-16 | meio de cultura celular |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10138292B2 (https=) |
| EP (2) | EP2651973B1 (https=) |
| JP (2) | JP6002675B2 (https=) |
| KR (3) | KR101966033B1 (https=) |
| CN (2) | CN103384680B (https=) |
| AU (1) | AU2011342904B2 (https=) |
| BR (2) | BR112013017629A2 (https=) |
| CA (2) | CA2826252C (https=) |
| IL (2) | IL226971B (https=) |
| MX (2) | MX343462B (https=) |
| SG (3) | SG10201510405PA (https=) |
| WO (2) | WO2012080844A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2536242C2 (ru) | 2007-09-28 | 2014-12-20 | Антродженезис Корпорейшн | Угнетение опухолей с помощью плацентарного перфузата человека и выделенных из плаценты человека вспомогательных натуральных клеток-киллеров |
| US10485829B2 (en) | 2009-11-17 | 2019-11-26 | Astellas Institute For Regenerative Medicine | Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells |
| MX342995B (es) | 2010-07-13 | 2016-10-21 | Anthrogenesis Corp | Métodos de generar células asesinas naturales. |
| CN103384680B (zh) | 2010-12-17 | 2015-08-26 | 拜奥拉米那公司 | 细胞培养基 |
| AU2012311233B2 (en) * | 2011-09-22 | 2017-03-16 | Sergey Rodin | Cell culture substrate comprising a laminin and a cadherin |
| WO2013080051A2 (en) | 2011-11-30 | 2013-06-06 | Biolamina Ab | Methods of enhancing genetic diagnosis |
| WO2013156855A1 (en) | 2012-04-20 | 2013-10-24 | Biolamina Ab | Maintenance of differentiated cells with laminins |
| US20130330825A1 (en) * | 2012-06-07 | 2013-12-12 | City Of Hope | Attachment substrates for directed differentiation of human embryonic stem cells in culture |
| DK2892996T3 (da) * | 2012-09-07 | 2019-10-07 | Biolamina Ab | Stamcellebank |
| EP2925856B1 (en) | 2012-12-03 | 2018-03-07 | Biolamina AB | Methods of producing rpe cells |
| AU2014215458A1 (en) | 2013-02-05 | 2015-08-13 | Anthrogenesis Corporation | Natural killer cells from placenta |
| EP3546568A3 (en) | 2013-07-02 | 2019-10-23 | National University of Singapore | Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221 |
| EP3064572B1 (en) * | 2013-11-01 | 2020-02-12 | BBHC Co. Ltd. | Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method |
| BR112016011096A2 (pt) | 2013-11-27 | 2017-09-19 | Kyoto Prefectural Public Univ Corp | Aplicação de laminina à cultura de célula endotelial da córnea |
| EP3213761B1 (en) * | 2014-10-31 | 2021-05-19 | Kyoto Prefectural Public University Corporation | Novel treatment of retina using laminin |
| CN121891508A (zh) * | 2014-10-31 | 2026-04-21 | 京都府公立大学法人 | 使用层粘连蛋白的新的角膜的治疗 |
| ES2703167T5 (es) | 2015-02-20 | 2022-09-30 | Inst Nat Sante Rech Med | Uso de una laminina para diferenciar células pluripotentes en células de linaje hepatocitario |
| WO2017034459A1 (en) * | 2015-08-23 | 2017-03-02 | Diamyd Medical Ab | New use |
| WO2017072580A1 (en) * | 2015-10-30 | 2017-05-04 | Biolamina Ab | Methods for producing hepatocytes |
| WO2017082026A1 (ja) * | 2015-11-10 | 2017-05-18 | 日機装株式会社 | 細胞支持複合体および細胞支持複合体の製造方法 |
| CN116121189A (zh) | 2016-03-30 | 2023-05-16 | 阿斯特利亚斯生物治疗股份公司 | 少突胶质细胞祖细胞组合物 |
| US20190211305A1 (en) * | 2016-08-25 | 2019-07-11 | Kyoto University | Method for Culturing Pluripotent Stem Cells on Specific Laminin |
| SG11201903428XA (en) | 2016-11-16 | 2019-05-30 | Cynata Therapeutics Ltd | Pluripotent stem cell assay |
| CN106591295B (zh) * | 2016-12-31 | 2019-10-25 | 贵州北科生物科技有限公司 | 一种多功能干细胞培养方法及所用培养基 |
| WO2018203834A1 (en) | 2017-05-05 | 2018-11-08 | National University Of Singapore | Methods for culturing human keratinocytes |
| IL281628B2 (en) | 2018-09-19 | 2025-06-01 | Lineage Cell Therapeutics Inc | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| WO2020154533A1 (en) | 2019-01-23 | 2020-07-30 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| CN111617105A (zh) * | 2019-04-03 | 2020-09-04 | 成熙(上海)生物科技有限公司 | 一种脂肪干细胞多细胞活性因子冻干粉的制备方法 |
| CN111621473A (zh) * | 2019-04-03 | 2020-09-04 | 成熙(上海)生物科技有限公司 | 一种新型人源脂肪干细胞制剂的制备方法 |
| WO2021233116A1 (zh) * | 2020-05-21 | 2021-11-25 | 北京大学 | 多能干细胞的成分明确、无异源的培养系统 |
| CN111569048B (zh) * | 2020-05-22 | 2023-04-18 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | LamG5肽在制备修复睾丸中支持细胞损伤的药物中的应用 |
| WO2025067551A1 (zh) * | 2024-05-16 | 2025-04-03 | 北京百普赛斯生物科技股份有限公司 | 活性增强的改造型Laminin 521蛋白及应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005252B1 (en) * | 2000-03-09 | 2006-02-28 | Wisconsin Alumni Research Foundation | Serum free cultivation of primate embryonic stem cells |
| ES2705683T3 (es) * | 2002-12-16 | 2019-03-26 | Technion Res & Dev Foundation | Medio de cultivo de células madre pluripotentes |
| CN101052712A (zh) * | 2004-09-08 | 2007-10-10 | 威斯康星校友研究基金会 | 培养人胚胎干细胞 |
| JP2006087396A (ja) | 2004-09-27 | 2006-04-06 | National Institute For Environmental Studies | 細胞培養基質及びその製造方法 |
| CN101180388A (zh) * | 2005-11-18 | 2008-05-14 | 银怎株式会社 | 用于胚胎干细胞未分化增殖的包括大田软海绵酸的组合物 |
| KR20080109775A (ko) * | 2006-02-23 | 2008-12-17 | 노보셀, 인크 | 분화가능한 세포를 배양하는데 유용한 조성물 및 방법 |
| CN101605885B (zh) | 2007-01-04 | 2013-03-27 | 卡尔·特吕格瓦松 | 能够使多能干细胞增殖的组合物及方法 |
| US10829733B2 (en) * | 2007-01-04 | 2020-11-10 | Biolamina Ab | Composition and method for enabling proliferation of pluripotent human stem cells |
| US8951799B2 (en) * | 2007-01-04 | 2015-02-10 | Biolamina Ab | Composition and method for enabling proliferation of pluripotent stem cells |
| BRPI0813787A2 (pt) | 2007-07-01 | 2014-10-07 | Lifescan Inc | Cultura de célula-tronco pluripotente isolada |
| SG188904A1 (en) * | 2008-03-17 | 2013-04-30 | Scripps Research Inst | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| JP5464443B2 (ja) * | 2008-03-31 | 2014-04-09 | オリエンタル酵母工業株式会社 | 多能性幹細胞を増殖させる方法 |
| EP2315827A1 (en) | 2008-07-07 | 2011-05-04 | Mass Institute Of Technology | Micropatterned co-culture systems as infectious disease analysis platforms |
| WO2010137746A1 (en) | 2009-05-29 | 2010-12-02 | Kyoto University | Method for producing induced pluripotent stem cells and method for culturing the same |
| JP5700301B2 (ja) * | 2009-06-03 | 2015-04-15 | 国立大学法人大阪大学 | 多能性幹細胞からの神経堤細胞群の分化誘導方法 |
| CA2707296A1 (en) | 2009-06-12 | 2010-12-12 | Richard T. Scott, Jr. | Method for relative quantitation of chromosomal dna copy number in a single or few cells |
| CN103384680B (zh) | 2010-12-17 | 2015-08-26 | 拜奥拉米那公司 | 细胞培养基 |
-
2011
- 2011-12-16 CN CN201180067656.XA patent/CN103384680B/zh active Active
- 2011-12-16 SG SG10201510405PA patent/SG10201510405PA/en unknown
- 2011-12-16 JP JP2013543905A patent/JP6002675B2/ja active Active
- 2011-12-16 KR KR1020197003578A patent/KR101966033B1/ko active Active
- 2011-12-16 CN CN201180067474.2A patent/CN103384679B/zh active Active
- 2011-12-16 US US13/328,156 patent/US10138292B2/en active Active
- 2011-12-16 MX MX2013006958A patent/MX343462B/es active IP Right Grant
- 2011-12-16 JP JP2013543904A patent/JP5990531B2/ja active Active
- 2011-12-16 EP EP11820800.8A patent/EP2651973B1/en active Active
- 2011-12-16 SG SG2013046701A patent/SG191215A1/en unknown
- 2011-12-16 CA CA2826252A patent/CA2826252C/en active Active
- 2011-12-16 AU AU2011342904A patent/AU2011342904B2/en active Active
- 2011-12-16 KR KR1020137018840A patent/KR101921350B1/ko active Active
- 2011-12-16 SG SG2013046727A patent/SG191216A1/en unknown
- 2011-12-16 BR BR112013017629A patent/BR112013017629A2/pt not_active Application Discontinuation
- 2011-12-16 WO PCT/IB2011/003265 patent/WO2012080844A1/en not_active Ceased
- 2011-12-16 MX MX2013006959A patent/MX345861B/es active IP Right Grant
- 2011-12-16 EP EP11820801.6A patent/EP2651974B1/en active Active
- 2011-12-16 US US13/328,145 patent/US8415156B2/en active Active
- 2011-12-16 BR BR112013017632A patent/BR112013017632A2/pt not_active Application Discontinuation
- 2011-12-16 CA CA2828794A patent/CA2828794C/en active Active
- 2011-12-16 KR KR1020137018841A patent/KR20140012047A/ko not_active Abandoned
- 2011-12-16 WO PCT/IB2011/003258 patent/WO2012080842A1/en not_active Ceased
-
2013
- 2013-06-16 IL IL226971A patent/IL226971B/en active IP Right Grant
-
2019
- 2019-10-26 IL IL270186A patent/IL270186B/en active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |