EP1948787A4 - Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells - Google Patents

Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells

Info

Publication number
EP1948787A4
EP1948787A4 EP05823886A EP05823886A EP1948787A4 EP 1948787 A4 EP1948787 A4 EP 1948787A4 EP 05823886 A EP05823886 A EP 05823886A EP 05823886 A EP05823886 A EP 05823886A EP 1948787 A4 EP1948787 A4 EP 1948787A4
Authority
EP
European Patent Office
Prior art keywords
composition
stem cells
embryonic stem
okadaic acid
undifferentiated proliferation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05823886A
Other languages
German (de)
French (fr)
Other versions
EP1948787A1 (en
Inventor
Seungkwon You
Byung Sun Yoon
Ki Dong Kim
Eun Kyung Jun
Jai Hee Moon
Gyuman Park
Sung Sik Kwak
Isaac Maeng
Bona Kim
Seung Jun Yoo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMGEN CO Ltd
Original Assignee
IMGEN CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMGEN CO Ltd filed Critical IMGEN CO Ltd
Publication of EP1948787A1 publication Critical patent/EP1948787A1/en
Publication of EP1948787A4 publication Critical patent/EP1948787A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP05823886A 2005-11-18 2005-11-18 Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells Withdrawn EP1948787A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2005/003925 WO2007058401A1 (en) 2005-11-18 2005-11-18 Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells

Publications (2)

Publication Number Publication Date
EP1948787A1 EP1948787A1 (en) 2008-07-30
EP1948787A4 true EP1948787A4 (en) 2008-12-31

Family

ID=38048770

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05823886A Withdrawn EP1948787A4 (en) 2005-11-18 2005-11-18 Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells

Country Status (4)

Country Link
EP (1) EP1948787A4 (en)
JP (1) JP2009506785A (en)
CN (1) CN101180388A (en)
WO (1) WO2007058401A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101135636B1 (en) * 2009-10-27 2012-04-17 서울대학교산학협력단 Method for producing mesenchymal stem cells from human pluripotent stem cells and mesenchymal stem cells produced by thereof
SG191216A1 (en) * 2010-12-17 2013-07-31 Biolamina Ab Cell culture medium

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2427322C (en) * 2000-12-22 2012-03-06 Aurox Llc Methods for cloning mammals using reprogrammed donor chromatin or donor cells

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
AFSHARI C A ET AL: "Induction of neoplastic progression in Syrian hamster embryo cells treated with protein phosphatase inhibitors.", CANCER RESEARCH 15 APR 1993, vol. 53, no. 8, 15 April 1993 (1993-04-15), pages 1777 - 1782, XP002504089, ISSN: 0008-5472 *
BOE R ET AL: "THE PROTEIN PHOSPHATASE INHIBITOR OKADAIC ACID INDUCES MORPHOLOGICAL CHANGES TYPICAL OF APOPTOSIS IN MAMALIAN CELLS", EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS, US, vol. 195, 1 January 1991 (1991-01-01), pages 237 - 246, XP002929317, ISSN: 0014-4827 *
FESSARD VALERIE ET AL: "Okadaic acid treatment induces DNA adduct formation in BHK21 C13 fibroblasts and HESV keratinocytes", MUTATION RESEARCH, vol. 361, no. 2-3, 1996, pages 133 - 141, XP009108744, ISSN: 0027-5107 *
NISHINA YUKIO ET AL: "Effects of protein phosphatase inhibition by okadaic acid on the differentiation of F9 embryonal carcinoma cells", EXPERIMENTAL CELL RESEARCH, vol. 217, no. 2, 1995, pages 288 - 293, XP002504078, ISSN: 0014-4827 *
SASAHARA YOJI ET AL: "Okadaic acid suppresses neural differentiation-dependent expression of the neurofilament-L gene in P19 embryonal carcinoma cells by post-transcriptional modification", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 42, 1996, pages 25950 - 25957, XP002504079, ISSN: 0021-9258 *
See also references of WO2007058401A1 *

Also Published As

Publication number Publication date
JP2009506785A (en) 2009-02-19
CN101180388A (en) 2008-05-14
EP1948787A1 (en) 2008-07-30
WO2007058401A1 (en) 2007-05-24

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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