DK3017038T3 - Differentiering af pluripotente stamceller og hjerteprogenitorceller i tværstribede kardiomyocytfibre under anvendelse af lamininer ln-511, ln-521 og ln-221 - Google Patents
Differentiering af pluripotente stamceller og hjerteprogenitorceller i tværstribede kardiomyocytfibre under anvendelse af lamininer ln-511, ln-521 og ln-221 Download PDFInfo
- Publication number
- DK3017038T3 DK3017038T3 DK14805655.9T DK14805655T DK3017038T3 DK 3017038 T3 DK3017038 T3 DK 3017038T3 DK 14805655 T DK14805655 T DK 14805655T DK 3017038 T3 DK3017038 T3 DK 3017038T3
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- laminines
- cardiro
- cardiomyocyty
- differentizing
- striped
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361842241P | 2013-07-02 | 2013-07-02 | |
PCT/IB2014/002289 WO2015004539A2 (en) | 2013-07-02 | 2014-07-02 | Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3017038T3 true DK3017038T3 (da) | 2019-08-19 |
Family
ID=52000884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14805655.9T DK3017038T3 (da) | 2013-07-02 | 2014-07-02 | Differentiering af pluripotente stamceller og hjerteprogenitorceller i tværstribede kardiomyocytfibre under anvendelse af lamininer ln-511, ln-521 og ln-221 |
Country Status (5)
Country | Link |
---|---|
US (2) | US11001807B2 (da) |
EP (2) | EP3546568A3 (da) |
DK (1) | DK3017038T3 (da) |
ES (1) | ES2742444T3 (da) |
WO (1) | WO2015004539A2 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2872620T (pt) * | 2012-07-12 | 2020-03-03 | Isletone Ab | Derivação e autorrenovação de células lsl+ e usos das mesmas |
WO2016043168A1 (ja) * | 2014-09-16 | 2016-03-24 | 国立大学法人大阪大学 | 多能性幹細胞由来心筋細胞集団の製造方法 |
DK3344758T3 (da) | 2015-09-01 | 2021-11-01 | Ncardia B V | Fremgangsmåde in vitro til differentiering af en human pluripotent stamcellepopulation i en kardiomyocytcellepopulation |
US10683486B2 (en) | 2015-10-30 | 2020-06-16 | Biolamina Ab | Methods for producing hepatocytes |
US11672830B2 (en) | 2016-04-15 | 2023-06-13 | Temple University-Of The Commonwealth System Of Higher Education | MicroRNA-294 and Lin28A as a driver of cardiac tissue proliferation in response to pathological injury |
WO2018022880A1 (en) * | 2016-07-28 | 2018-02-01 | Sanofi | Compositions and methods for muscle progenitor cell-based therapies |
WO2018035574A1 (en) * | 2016-08-26 | 2018-03-01 | The University Of Queensland | Cardiomyocyte maturation |
CN109937251B (zh) | 2016-11-11 | 2023-12-29 | 国立大学法人大阪大学 | 由多能干细胞向体细胞的分化诱导方法 |
CN108265029A (zh) * | 2016-12-30 | 2018-07-10 | 复旦大学 | 人类多能干细胞来源的人类心室肌细胞的筛选及制备方法 |
WO2018236289A1 (en) * | 2017-06-22 | 2018-12-27 | National University Of Singapore | DIFFERENTIATION OF PLURIPOTENT STEM CELLS AND CARDIAC CARDIAC PROGENITOR CELLS STRIATED WITH LAMININS LN-511, LN-521 AND LN-221 |
CN113337458A (zh) * | 2021-06-02 | 2021-09-03 | 呈诺再生医学科技(珠海横琴新区)有限公司 | 一种提高多能干细胞定向诱导心肌细胞产量及纯度的方法 |
WO2023087109A1 (en) * | 2021-11-17 | 2023-05-25 | The Governing Council Of The University Of Toronto | Maturation medium for pluripotent stem cell-derived cardiomyocytes |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5523226A (en) * | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
KR101921350B1 (ko) * | 2010-12-17 | 2018-11-22 | 바이오라미나 에이비 | 인간 다능성 줄기세포를 유지하기 위한 시스템 |
US20130330825A1 (en) * | 2012-06-07 | 2013-12-12 | City Of Hope | Attachment substrates for directed differentiation of human embryonic stem cells in culture |
PT2872620T (pt) * | 2012-07-12 | 2020-03-03 | Isletone Ab | Derivação e autorrenovação de células lsl+ e usos das mesmas |
-
2014
- 2014-07-02 EP EP19175399.5A patent/EP3546568A3/en active Pending
- 2014-07-02 ES ES14805655T patent/ES2742444T3/es active Active
- 2014-07-02 EP EP14805655.9A patent/EP3017038B1/en active Active
- 2014-07-02 DK DK14805655.9T patent/DK3017038T3/da active
- 2014-07-02 WO PCT/IB2014/002289 patent/WO2015004539A2/en active Application Filing
- 2014-07-02 US US14/895,669 patent/US11001807B2/en active Active
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2021
- 2021-04-09 US US17/226,611 patent/US20210301257A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3017038B1 (en) | 2019-05-22 |
EP3546568A2 (en) | 2019-10-02 |
EP3017038A2 (en) | 2016-05-11 |
US20210301257A1 (en) | 2021-09-30 |
US20160122717A1 (en) | 2016-05-05 |
WO2015004539A2 (en) | 2015-01-15 |
ES2742444T3 (es) | 2020-02-14 |
WO2015004539A3 (en) | 2015-10-22 |
US11001807B2 (en) | 2021-05-11 |
EP3546568A3 (en) | 2019-10-23 |
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