MX345861B - Laminina-521 recombinante. - Google Patents

Laminina-521 recombinante.

Info

Publication number
MX345861B
MX345861B MX2013006959A MX2013006959A MX345861B MX 345861 B MX345861 B MX 345861B MX 2013006959 A MX2013006959 A MX 2013006959A MX 2013006959 A MX2013006959 A MX 2013006959A MX 345861 B MX345861 B MX 345861B
Authority
MX
Mexico
Prior art keywords
laminin
stem cells
single cell
embryonic stem
recombinant
Prior art date
Application number
MX2013006959A
Other languages
English (en)
Other versions
MX2013006959A (es
Inventor
Tryggvason Karl
Rodin Sergey
Original Assignee
Biolamina Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolamina Ab filed Critical Biolamina Ab
Publication of MX2013006959A publication Critical patent/MX2013006959A/es
Publication of MX345861B publication Critical patent/MX345861B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/605—Nanog
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/608—Lin28
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a una composición que permite la autorrenovacón de células madre pluripotentes cultivadas in vitro, que comprende un medio de crecimiento y un recubrimiento, el recubrimiento comprende laminina 521 recombinante (laminina-11) aislada el cual está libre de cadenas de laminina contaminantes detectables.
MX2013006959A 2010-12-17 2011-12-16 Laminina-521 recombinante. MX345861B (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201061424273P 2010-12-17 2010-12-17
US201161488353P 2011-05-20 2011-05-20
US201161533063P 2011-09-09 2011-09-09
US201161537940P 2011-09-22 2011-09-22
US201161565380P 2011-11-30 2011-11-30
US201161565849P 2011-12-01 2011-12-01
PCT/IB2011/003258 WO2012080842A1 (en) 2010-12-17 2011-12-16 Recombinant laminin-521

Publications (2)

Publication Number Publication Date
MX2013006959A MX2013006959A (es) 2013-12-06
MX345861B true MX345861B (es) 2017-02-20

Family

ID=45755415

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013006958A MX343462B (es) 2010-12-17 2011-12-16 Medio del cultivo celular.
MX2013006959A MX345861B (es) 2010-12-17 2011-12-16 Laminina-521 recombinante.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2013006958A MX343462B (es) 2010-12-17 2011-12-16 Medio del cultivo celular.

Country Status (12)

Country Link
US (2) US8415156B2 (es)
EP (2) EP2651974B1 (es)
JP (2) JP6002675B2 (es)
KR (3) KR101921350B1 (es)
CN (2) CN103384679B (es)
AU (1) AU2011342904B2 (es)
BR (2) BR112013017632A2 (es)
CA (2) CA2826252C (es)
IL (2) IL226971B (es)
MX (2) MX343462B (es)
SG (3) SG191216A1 (es)
WO (2) WO2012080844A1 (es)

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CN107828727A (zh) 2010-07-13 2018-03-23 人类起源公司 产生自然杀伤细胞的方法、由此获得的细胞群体及其用途
MX343462B (es) * 2010-12-17 2016-11-07 Biolamina Ab Medio del cultivo celular.
SG10201704803RA (en) * 2011-09-22 2017-07-28 Karl Tryggvason Cell culture substrate comprising a laminin and a cadherin
WO2013080051A2 (en) 2011-11-30 2013-06-06 Biolamina Ab Methods of enhancing genetic diagnosis
EP3282009A1 (en) 2012-04-20 2018-02-14 Biolamina AB Maintenance of differentiated cells with laminins
US20130330825A1 (en) * 2012-06-07 2013-12-12 City Of Hope Attachment substrates for directed differentiation of human embryonic stem cells in culture
WO2014037807A2 (en) * 2012-09-07 2014-03-13 Biolamina Ab Stem cell bank
PT2925856T (pt) 2012-12-03 2018-06-15 Biolamina Ab Métodos de produção de células epr
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US11001807B2 (en) 2013-07-02 2021-05-11 National University Of Singapore Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins LN-511, LN-521 and LN-221
JP6700175B2 (ja) * 2013-11-01 2020-05-27 ビービーエイチシー・カンパニー・リミテッドＢｂｈｃ Ｃｏ．， Ｌｔｄ． 間葉系幹細胞から誘導多能性幹細胞を製造する方法及びその方法によって製造された誘導多能性幹細胞
ES2763433T3 (es) 2013-11-27 2020-05-28 Kyoto Prefectural Public Univ Corp Aplicación de laminina a cultivos de células endoteliales de la córnea
EP3213761B1 (en) * 2014-10-31 2021-05-19 Kyoto Prefectural Public University Corporation Novel treatment of retina using laminin
MX387839B (es) 2014-10-31 2025-03-04 Senju Pharma Co Laminina para usarse en el tratamiento de una enfermedad, un trastorno o una afección de un endotelio de córnea.
SI3059307T2 (sl) 2015-02-20 2022-08-31 Inserm(Institut National De La Sante Et De La Recherche Medicale) Uporaba laminina za diferenciacijo pluripotentnih celic v hepatocite
WO2017034459A1 (en) * 2015-08-23 2017-03-02 Diamyd Medical Ab New use
US10683486B2 (en) * 2015-10-30 2020-06-16 Biolamina Ab Methods for producing hepatocytes
JP6605618B2 (ja) 2015-11-10 2019-11-20 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
JP2019509744A (ja) 2016-03-30 2019-04-11 アステリアス バイオセラピューティクス インコーポレイテッド オリゴデンドロサイト前駆細胞組成物
US20190211305A1 (en) * 2016-08-25 2019-07-11 Kyoto University Method for Culturing Pluripotent Stem Cells on Specific Laminin
AU2017361117B9 (en) 2016-11-16 2022-03-24 Cynata Therapeutics Limited Pluripotent stem cell assay
CN106591295B (zh) * 2016-12-31 2019-10-25 贵州北科生物科技有限公司 一种多功能干细胞培养方法及所用培养基
WO2018203834A1 (en) * 2017-05-05 2018-11-08 National University Of Singapore Methods for culturing human keratinocytes
AU2019342741B2 (en) 2018-09-19 2025-12-11 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
JP7469317B2 (ja) * 2019-01-23 2024-04-16 アステリアス バイオセラピューティクス インコーポレイテッド ヒト多能性幹細胞からの背側由来オリゴデンドロサイト前駆細胞
CN111617105A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种脂肪干细胞多细胞活性因子冻干粉的制备方法
CN111621473A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种新型人源脂肪干细胞制剂的制备方法
WO2021233116A1 (zh) * 2020-05-21 2021-11-25 北京大学 多能干细胞的成分明确、无异源的培养系统
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Also Published As

Publication number Publication date
CN103384680B (zh) 2015-08-26
WO2012080842A1 (en) 2012-06-21
JP2013545489A (ja) 2013-12-26
CN103384680A (zh) 2013-11-06
JP2014501101A (ja) 2014-01-20
MX2013006958A (es) 2013-12-16
CA2828794A1 (en) 2012-06-21
JP5990531B2 (ja) 2016-09-14
AU2011342904B2 (en) 2016-05-12
KR20190018024A (ko) 2019-02-20
SG191215A1 (en) 2013-07-31
SG191216A1 (en) 2013-07-31
SG10201510405PA (en) 2016-01-28
EP2651974B1 (en) 2015-09-16
US10138292B2 (en) 2018-11-27
US20120156254A1 (en) 2012-06-21
KR101921350B1 (ko) 2018-11-22
US20120156782A1 (en) 2012-06-21
KR101966033B1 (ko) 2019-04-04
EP2651973A1 (en) 2013-10-23
CA2826252C (en) 2018-12-04
EP2651973B1 (en) 2016-08-31
MX2013006959A (es) 2013-12-06
KR20140016881A (ko) 2014-02-10
CN103384679A (zh) 2013-11-06
EP2651974A1 (en) 2013-10-23
US8415156B2 (en) 2013-04-09
CA2826252A1 (en) 2012-06-21
CN103384679B (zh) 2015-08-26
JP6002675B2 (ja) 2016-10-05
MX343462B (es) 2016-11-07
KR20140012047A (ko) 2014-01-29
WO2012080844A1 (en) 2012-06-21
IL270186B (en) 2020-08-31
BR112013017632A2 (pt) 2016-10-11
CA2828794C (en) 2021-07-13
IL226971B (en) 2018-04-30
BR112013017629A2 (pt) 2017-04-18

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