MX345861B - Laminina-521 recombinante. - Google Patents

Laminina-521 recombinante.

Info

Publication number
MX345861B
MX345861B MX2013006959A MX2013006959A MX345861B MX 345861 B MX345861 B MX 345861B MX 2013006959 A MX2013006959 A MX 2013006959A MX 2013006959 A MX2013006959 A MX 2013006959A MX 345861 B MX345861 B MX 345861B
Authority
MX
Mexico
Prior art keywords
laminin
stem cells
single cell
embryonic stem
recombinant
Prior art date
Application number
MX2013006959A
Other languages
English (en)
Other versions
MX2013006959A (es
Inventor
Tryggvason Karl
Rodin Sergey
Original Assignee
Biolamina Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolamina Ab filed Critical Biolamina Ab
Publication of MX2013006959A publication Critical patent/MX2013006959A/es
Publication of MX345861B publication Critical patent/MX345861B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/605—Nanog
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/608—Lin28
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención se refiere a una composición que permite la autorrenovacón de células madre pluripotentes cultivadas in vitro, que comprende un medio de crecimiento y un recubrimiento, el recubrimiento comprende laminina 521 recombinante (laminina-11) aislada el cual está libre de cadenas de laminina contaminantes detectables.
MX2013006959A 2010-12-17 2011-12-16 Laminina-521 recombinante. MX345861B (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201061424273P 2010-12-17 2010-12-17
US201161488353P 2011-05-20 2011-05-20
US201161533063P 2011-09-09 2011-09-09
US201161537940P 2011-09-22 2011-09-22
US201161565380P 2011-11-30 2011-11-30
US201161565849P 2011-12-01 2011-12-01
PCT/IB2011/003258 WO2012080842A1 (en) 2010-12-17 2011-12-16 Recombinant laminin-521

Publications (2)

Publication Number Publication Date
MX2013006959A MX2013006959A (es) 2013-12-06
MX345861B true MX345861B (es) 2017-02-20

Family

ID=45755415

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013006958A MX343462B (es) 2010-12-17 2011-12-16 Medio del cultivo celular.
MX2013006959A MX345861B (es) 2010-12-17 2011-12-16 Laminina-521 recombinante.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2013006958A MX343462B (es) 2010-12-17 2011-12-16 Medio del cultivo celular.

Country Status (12)

Country Link
US (2) US8415156B2 (es)
EP (2) EP2651974B1 (es)
JP (2) JP5990531B2 (es)
KR (3) KR101966033B1 (es)
CN (2) CN103384680B (es)
AU (1) AU2011342904B2 (es)
BR (2) BR112013017629A2 (es)
CA (2) CA2828794C (es)
IL (2) IL226971B (es)
MX (2) MX343462B (es)
SG (3) SG191215A1 (es)
WO (2) WO2012080842A1 (es)

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KR20210127819A (ko) 2007-09-28 2021-10-22 안트로제네시스 코포레이션 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법
KR20120102709A (ko) 2009-11-17 2012-09-18 어드밴스드 셀 테크놀로지, 인코포레이티드 인간 ｒｐｅ 세포의 생산 방법 및 인간 ｒｐｅ 세포의 제약 제제
KR20200077613A (ko) 2010-07-13 2020-06-30 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
WO2012080842A1 (en) 2010-12-17 2012-06-21 Biolamina Ab Recombinant laminin-521
US10240124B2 (en) * 2011-09-22 2019-03-26 Biolamina Ab Cell culture substrate comprising a laminin and a cadherin
US9828630B2 (en) 2011-11-30 2017-11-28 Biolamina Ab Methods of enhancing genetic diagnosis
EP2838992B1 (en) * 2012-04-20 2017-11-08 Biolamina AB Maintenance of differentiated cells with laminins
US20130330825A1 (en) * 2012-06-07 2013-12-12 City Of Hope Attachment substrates for directed differentiation of human embryonic stem cells in culture
US9719066B2 (en) 2012-09-07 2017-08-01 Biolamina Ab Stem cell bank
WO2014087244A2 (en) 2012-12-03 2014-06-12 Biolamina Ab Methods of producing rpe cells
JP2016506968A (ja) 2013-02-05 2016-03-07 アントフロゲネシス コーポレーション 胎盤由来のナチュラルキラー細胞
EP3017038B1 (en) * 2013-07-02 2019-05-22 National University of Singapore Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221
SG11201508796SA (en) * 2013-11-01 2015-11-27 Bbhc Co Ltd Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method
MX2016006915A (es) 2013-11-27 2017-01-23 Kyoto Prefectural Public Univ Corp Aplicacion de laminina a cultivo de celulas endoteliales de la cornea.
CN107073067A (zh) * 2014-10-31 2017-08-18 京都府公立大学法人 使用层粘连蛋白的新的角膜的治疗
EP3213761B1 (en) * 2014-10-31 2021-05-19 Kyoto Prefectural Public University Corporation Novel treatment of retina using laminin
RS58070B2 (sr) 2015-02-20 2022-10-31 Inst Nat Sante Rech Med Upotreba laminina za diferencijaciju pluripotentnih ćelija u ćelije hepatocitne linije
WO2017034459A1 (en) * 2015-08-23 2017-03-02 Diamyd Medical Ab New use
EP3368657B1 (en) * 2015-10-30 2021-06-30 Biolamina AB Methods for producing hepatocytes
JP6605618B2 (ja) * 2015-11-10 2019-11-20 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
CN109219657A (zh) 2016-03-30 2019-01-15 阿斯特利亚斯生物治疗股份公司 少突胶质细胞祖细胞组合物
WO2018038242A1 (ja) * 2016-08-25 2018-03-01 国立大学法人京都大学 特定のラミニン上での多能性幹細胞の培養方法
KR102516844B1 (ko) 2016-11-16 2023-04-04 시나타 세라퓨틱스 엘티디 만능성 줄기 세포 분석
CN106591295B (zh) * 2016-12-31 2019-10-25 贵州北科生物科技有限公司 一种多功能干细胞培养方法及所用培养基
AU2018262323A1 (en) 2017-05-05 2019-11-21 National University Of Singapore Methods for culturing human keratinocytes
CA3127213A1 (en) * 2019-01-23 2020-07-30 Asterias Biotherapeutics, Inc. Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
CN111621473A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种新型人源脂肪干细胞制剂的制备方法
CN111617105A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种脂肪干细胞多细胞活性因子冻干粉的制备方法
WO2021233116A1 (zh) * 2020-05-21 2021-11-25 北京大学 多能干细胞的成分明确、无异源的培养系统
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WO2012080842A1 (en) 2010-12-17 2012-06-21 Biolamina Ab Recombinant laminin-521

Also Published As

Publication number Publication date
CA2828794C (en) 2021-07-13
KR101966033B1 (ko) 2019-04-04
JP2013545489A (ja) 2013-12-26
AU2011342904B2 (en) 2016-05-12
MX343462B (es) 2016-11-07
CA2828794A1 (en) 2012-06-21
EP2651973B1 (en) 2016-08-31
IL226971B (en) 2018-04-30
KR20140016881A (ko) 2014-02-10
MX2013006958A (es) 2013-12-16
CN103384679B (zh) 2015-08-26
KR20190018024A (ko) 2019-02-20
US20120156782A1 (en) 2012-06-21
CN103384680B (zh) 2015-08-26
EP2651973A1 (en) 2013-10-23
EP2651974A1 (en) 2013-10-23
CN103384680A (zh) 2013-11-06
CA2826252C (en) 2018-12-04
CA2826252A1 (en) 2012-06-21
SG191216A1 (en) 2013-07-31
IL270186B (en) 2020-08-31
KR20140012047A (ko) 2014-01-29
CN103384679A (zh) 2013-11-06
US20120156254A1 (en) 2012-06-21
JP2014501101A (ja) 2014-01-20
SG10201510405PA (en) 2016-01-28
WO2012080844A1 (en) 2012-06-21
BR112013017629A2 (pt) 2017-04-18
EP2651974B1 (en) 2015-09-16
US10138292B2 (en) 2018-11-27
JP5990531B2 (ja) 2016-09-14
WO2012080842A1 (en) 2012-06-21
SG191215A1 (en) 2013-07-31
US8415156B2 (en) 2013-04-09
MX2013006959A (es) 2013-12-06
BR112013017632A2 (pt) 2016-10-11
JP6002675B2 (ja) 2016-10-05
KR101921350B1 (ko) 2018-11-22

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