BR112013013256A2 - método para a produção de ácido 2-bromo-4,5-dialcoxi- benzóico - Google Patents
método para a produção de ácido 2-bromo-4,5-dialcoxi- benzóicoInfo
- Publication number
- BR112013013256A2 BR112013013256A2 BR112013013256A BR112013013256A BR112013013256A2 BR 112013013256 A2 BR112013013256 A2 BR 112013013256A2 BR 112013013256 A BR112013013256 A BR 112013013256A BR 112013013256 A BR112013013256 A BR 112013013256A BR 112013013256 A2 BR112013013256 A2 BR 112013013256A2
- Authority
- BR
- Brazil
- Prior art keywords
- bromo
- production
- dialkoxybenzoic acid
- dialkoxybenzoic
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010-272668 | 2010-12-07 | ||
| JP2010272668 | 2010-12-07 | ||
| PCT/JP2011/078169 WO2012077673A1 (ja) | 2010-12-07 | 2011-12-06 | ２－ブロモ－４，５－ジアルコキシ安息香酸の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013013256A2 true BR112013013256A2 (pt) | 2016-09-13 |
| BR112013013256B1 BR112013013256B1 (pt) | 2020-10-27 |
Family
ID=46207161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013013256-6A BR112013013256B1 (pt) | 2010-12-07 | 2011-12-06 | método para a produção de ácido 2-bromo-4,5-dialcoxi- benzóico |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9096511B2 (pt) |
| EP (1) | EP2650277B1 (pt) |
| JP (1) | JP5853957B2 (pt) |
| KR (1) | KR101906617B1 (pt) |
| CN (1) | CN103237781B (pt) |
| AU (1) | AU2011339438B2 (pt) |
| BR (1) | BR112013013256B1 (pt) |
| CA (1) | CA2819119C (pt) |
| ES (1) | ES2679280T3 (pt) |
| MX (1) | MX338808B (pt) |
| RU (1) | RU2576520C2 (pt) |
| SG (1) | SG190721A1 (pt) |
| TW (1) | TWI498318B (pt) |
| WO (1) | WO2012077673A1 (pt) |
| ZA (1) | ZA201303500B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104447612A (zh) * | 2013-09-16 | 2015-03-25 | 天津市汉康医药生物技术有限公司 | 阿考替胺水合物晶型及其制备方法和用途 |
| CN103508893A (zh) * | 2013-10-09 | 2014-01-15 | 江苏弘和药物研发有限公司 | 一种2-羟基-4,5-二甲氧基苯甲酸苯酯的合成方法 |
| CN103896873B (zh) * | 2013-10-23 | 2015-11-25 | 山东诚创医药技术开发有限公司 | 一种盐酸阿考替胺的精制方法 |
| CN104672163A (zh) * | 2013-12-03 | 2015-06-03 | 山东富创医药科技有限公司 | 一种盐酸阿考替胺的制备方法 |
| CN104045606B (zh) * | 2014-07-11 | 2015-09-30 | 杭州新博思生物医药有限公司 | 一锅法制备阿考替胺盐酸盐的方法 |
| CN105439977A (zh) * | 2014-09-26 | 2016-03-30 | 广州朗圣药业有限公司 | 一种阿考替胺及其盐酸盐的制备方法 |
| US10364206B2 (en) | 2015-04-13 | 2019-07-30 | Sumitomo Seika Chemicals Co., Ltd. | Method for producing 2-halogenated benzoic acids |
| CN105924406B (zh) * | 2016-05-04 | 2018-04-10 | 河北国龙制药有限公司 | 一种盐酸阿考替胺三水合物的制备方法 |
| CN106316979B (zh) * | 2016-08-22 | 2018-11-27 | 山东罗欣药业集团股份有限公司 | 一种盐酸阿考替胺的制备方法 |
| EP3974021B1 (en) | 2017-06-30 | 2023-06-14 | ONWARD Medical N.V. | A system for neuromodulation |
| DE18205821T1 (de) | 2018-11-13 | 2020-12-24 | Gtx Medical B.V. | Steuerungssystem zur bewegungsrekonstruktion und/oder wiederherstellung für einen patienten |
| EP3695878B1 (en) | 2019-02-12 | 2023-04-19 | ONWARD Medical N.V. | A system for neuromodulation |
| DE19211698T1 (de) | 2019-11-27 | 2021-09-02 | Onward Medical B.V. | Neuromodulation system |
| CN111440128A (zh) * | 2020-05-27 | 2020-07-24 | 廊坊市泽康医药科技有限公司 | 一种盐酸阿考替胺杂质的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU76781A1 (ru) * | 1948-11-05 | 1948-11-30 | Н.М. Косникова | Способ получени альфа-бромпиридина |
| DE4423356A1 (de) * | 1994-07-04 | 1996-01-11 | Bayer Ag | Verbessertes Verfahren zur Herstellung von 3,5-Dihydroxy-4-brombenzoesäure |
| JP2003252826A (ja) | 2002-02-26 | 2003-09-10 | Mitsui Chemicals Inc | アルコキシ安息香酸類の製造方法 |
| CA2838137C (en) * | 2004-08-23 | 2016-02-09 | Zeria Pharmaceutical Co., Ltd. | Phenyl-2-hydroxy-4,5-dimethoxy-benzoate and derivatives |
| US8586761B2 (en) | 2004-08-23 | 2013-11-19 | Zeria Pharmaceutical Co., Ltd. | Method for producing aminothiazole derivative and production intermediate |
| US20090099175A1 (en) * | 2006-03-01 | 2009-04-16 | Arrington Mark P | Phosphodiesterase 10 inhibitors |
| US7335791B1 (en) | 2006-11-28 | 2008-02-26 | E.I. Du Pont De Nemours And Company | Process for the synthesis of hydroxy aromatic acids |
-
2011
- 2011-12-06 WO PCT/JP2011/078169 patent/WO2012077673A1/ja active Application Filing
- 2011-12-06 RU RU2013130734/04A patent/RU2576520C2/ru active
- 2011-12-06 BR BR112013013256-6A patent/BR112013013256B1/pt active IP Right Grant
- 2011-12-06 MX MX2013006405A patent/MX338808B/es active IP Right Grant
- 2011-12-06 CA CA2819119A patent/CA2819119C/en active Active
- 2011-12-06 AU AU2011339438A patent/AU2011339438B2/en active Active
- 2011-12-06 CN CN201180058574.9A patent/CN103237781B/zh active Active
- 2011-12-06 US US13/991,242 patent/US9096511B2/en active Active
- 2011-12-06 EP EP11847027.7A patent/EP2650277B1/en active Active
- 2011-12-06 JP JP2012547868A patent/JP5853957B2/ja active Active
- 2011-12-06 TW TW100144918A patent/TWI498318B/zh active
- 2011-12-06 SG SG2013041397A patent/SG190721A1/en unknown
- 2011-12-06 KR KR1020137012478A patent/KR101906617B1/ko active IP Right Grant
- 2011-12-06 ES ES11847027.7T patent/ES2679280T3/es active Active
-
2013
- 2013-05-14 ZA ZA2013/03500A patent/ZA201303500B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG190721A1 (en) | 2013-07-31 |
| JPWO2012077673A1 (ja) | 2014-05-19 |
| CA2819119A1 (en) | 2012-06-14 |
| ES2679280T3 (es) | 2018-08-23 |
| ZA201303500B (en) | 2014-07-30 |
| EP2650277B1 (en) | 2018-07-11 |
| CN103237781B (zh) | 2016-01-20 |
| EP2650277A1 (en) | 2013-10-16 |
| CN103237781A (zh) | 2013-08-07 |
| RU2576520C2 (ru) | 2016-03-10 |
| TW201229024A (en) | 2012-07-16 |
| CA2819119C (en) | 2018-02-13 |
| MX2013006405A (es) | 2013-08-26 |
| KR20130140006A (ko) | 2013-12-23 |
| AU2011339438A1 (en) | 2013-06-27 |
| US20130253222A1 (en) | 2013-09-26 |
| RU2013130734A (ru) | 2015-01-20 |
| WO2012077673A1 (ja) | 2012-06-14 |
| KR101906617B1 (ko) | 2018-10-10 |
| US9096511B2 (en) | 2015-08-04 |
| AU2011339438B2 (en) | 2016-05-26 |
| EP2650277A4 (en) | 2015-01-21 |
| JP5853957B2 (ja) | 2016-02-09 |
| MX338808B (es) | 2016-04-29 |
| TWI498318B (zh) | 2015-09-01 |
| BR112013013256B1 (pt) | 2020-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112013013256A2 (pt) | método para a produção de ácido 2-bromo-4,5-dialcoxi- benzóico | |
| BR112013012801A2 (pt) | método para a produção de um calçado e calçado | |
| BR112014003798A2 (pt) | método para fabricar um composto, e, composto | |
| BR112013031209A2 (pt) | método para produção de hidrógéis | |
| BR112013002925A2 (pt) | processo para a síntese de ácido 2,5-furandicarboxílico | |
| BR112013019911A2 (pt) | método para a produção de um ácido poli-hidróxi-carboxílico | |
| BR112012001937A2 (pt) | método para a produção de 2,2-difluoroetilamina | |
| BRPI0922710A8 (pt) | método para a produção de plaquetas | |
| BR112013030423A2 (pt) | método para produção de biocoque | |
| BR112013031120A2 (pt) | processo para a preparação de ácido fórmico | |
| BR112013008883A2 (pt) | processo para a fabricação de di-hidropteridinonas | |
| BR112013006230A2 (pt) | processo para a preparação de uma n-fenilhidroxilamina substituída | |
| BRPI0919835A2 (pt) | método para a produção de polímeros | |
| BR112013012361A2 (pt) | método para a fabricação de pneumático. | |
| BR112013019524A2 (pt) | método para a produção de 2,3-butanodiol por fermentação | |
| BR112013019525A2 (pt) | método para a produção de 2,3-butanodiol por fermentação | |
| BR112013016201A2 (pt) | processo para a produção de enzimas | |
| FR2961808B1 (fr) | Procede de production de methionine | |
| BR112012025490A2 (pt) | ''método para produção de 1,5 oebtanodiamina'' | |
| BR112013015601A2 (pt) | método para produzir 2-(triazinilcarbonil) sulfonanilidas | |
| BR112013017831A2 (pt) | método para a preparação de ácido nicotínico | |
| BRPI1010841A2 (pt) | método para a fabricação de fluoroalquilnitrilas | |
| BR112012017828A2 (pt) | ''método para a produção de um produto químico por fermentação contínua'' | |
| BR112013014581A2 (pt) | método para a fabricação de um diorgano-di-halossilano | |
| BR112014001469A2 (pt) | métodos para a produção de ácido orgânico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/12/2011, OBSERVADAS AS CONDICOES LEGAIS. |