BR112013005278A2 - produtos vasculares acelulares - Google Patents
produtos vasculares acelularesInfo
- Publication number
- BR112013005278A2 BR112013005278A2 BR112013005278A BR112013005278A BR112013005278A2 BR 112013005278 A2 BR112013005278 A2 BR 112013005278A2 BR 112013005278 A BR112013005278 A BR 112013005278A BR 112013005278 A BR112013005278 A BR 112013005278A BR 112013005278 A2 BR112013005278 A2 BR 112013005278A2
- Authority
- BR
- Brazil
- Prior art keywords
- products
- acellular
- tissue matrix
- vascular tissue
- vascular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3625—Vascular tissue, e.g. heart valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Battery Electrode And Active Subsutance (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
produtos vasculares acelulares. a presente invenção refere-se a um produto que compreende uma matriz de tecido vascular xenogênico acelular natural que possui pelo menos 80% de redução no conteúdo de dna, em comparação com uma matriz de tecido vascular de controle não tratada e sendo antigenicamente inerte por estar substancialmente livre de epitopos capazes de reagir com os anticorpos humanos pré-formados e também sem ter a capacidade de ativar o complemento substancialmente. a invenção também inclui métodos de preparação de tais produtos e utilizaçoes dos produtos, especialmente em cirurgia de bypass.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1016150.3 | 2010-09-27 | ||
GBGB1016150.3A GB201016150D0 (en) | 2010-09-27 | 2010-09-27 | Acellular vascular products |
GB1020846.0 | 2010-12-09 | ||
GBGB1020846.0A GB201020846D0 (en) | 2010-12-09 | 2010-12-09 | Acellular vascular products |
PCT/GB2011/051817 WO2012042250A1 (en) | 2010-09-27 | 2011-09-26 | Acellular vascular products |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013005278A2 true BR112013005278A2 (pt) | 2016-05-17 |
BR112013005278B1 BR112013005278B1 (pt) | 2019-07-09 |
Family
ID=45892022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013005278-3A BR112013005278B1 (pt) | 2010-09-27 | 2011-09-26 | Produtos que comprendem matriz de tecido vascular xenogênico acelular e método de preparação de um tecido vascular xenogênico acelular |
Country Status (11)
Country | Link |
---|---|
US (1) | US9510933B2 (pt) |
EP (1) | EP2621548B1 (pt) |
JP (1) | JP5881711B2 (pt) |
CN (1) | CN103124570B (pt) |
AU (2) | AU2011309900B2 (pt) |
BR (1) | BR112013005278B1 (pt) |
CA (1) | CA2808478C (pt) |
ES (1) | ES2628441T3 (pt) |
HK (1) | HK1185292A1 (pt) |
PL (1) | PL2621548T3 (pt) |
WO (1) | WO2012042250A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10058630B2 (en) * | 2012-10-22 | 2018-08-28 | Concievalve, Llc | Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis |
US10213526B2 (en) | 2014-03-21 | 2019-02-26 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix |
AU2017207015B2 (en) | 2016-01-13 | 2022-08-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Vascular extracellular matrix hydrogel |
CN113425912A (zh) * | 2020-03-23 | 2021-09-24 | 成都中科奥格生物科技有限公司 | 一种脱细胞真皮材料及其制备方法和用途 |
CN113368306A (zh) * | 2020-03-23 | 2021-09-10 | 成都中科奥格生物科技有限公司 | 低免疫原性生物材料及其制备方法和用途 |
CN113425905A (zh) * | 2020-03-23 | 2021-09-24 | 成都中科奥格生物科技有限公司 | 一种血管材料及其制备方法和用途 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8618374D0 (en) * | 1986-07-28 | 1986-09-03 | Hsc Res Dev Corp | Biological vascular prostheses |
US20040208842A1 (en) * | 2001-09-18 | 2004-10-21 | Ritchie Branson W. | Antimicrobial cleansing compositions and methods of use |
GB2375771A (en) | 2001-05-24 | 2002-11-27 | Univ Leeds | Decellularisation of tissue implant material |
EP1517715A2 (en) | 2002-06-28 | 2005-03-30 | Cardio, Inc. | Decellularized tissue |
KR20070002057A (ko) * | 2004-03-17 | 2007-01-04 | 레비비코르 인코포레이션 | 기능성 알파 1,3 갈락토실트랜스펙션스페라제의 어떠한발현도 결여된 동물로부터 유래된 조직 산물 |
US20050266390A1 (en) * | 2004-06-01 | 2005-12-01 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
EP1869082B1 (en) | 2005-03-04 | 2011-04-13 | The Board Of Trustees Of The University Of Illinois | Coagulation and fibrinolytic cascades modulator |
PL2094325T3 (pl) * | 2006-11-16 | 2012-03-30 | Tissue Regenix Ltd | Przygotowanie tkanki do przeszczepu łąkotki |
GB0622846D0 (en) | 2006-11-16 | 2006-12-27 | Univ Leeds | Preparation of tissue for meniscal implantation |
US20080306610A1 (en) * | 2007-06-07 | 2008-12-11 | Zimmer Orthobiologics, Inc. | Tissue processing for nonimmunogenic implants |
WO2009009620A2 (en) * | 2007-07-10 | 2009-01-15 | Lifecell Corporation | Acellular tissue matrix compositions for tissue repair |
CN100594041C (zh) * | 2007-12-27 | 2010-03-17 | 南京医科大学附属南京儿童医院 | 猪血管脱细胞的支架的化学与物理结合的制备方法 |
US8735054B1 (en) * | 2008-01-04 | 2014-05-27 | Lifecell Corporation | Acellular tissue matrix preservation solution |
CN101474426B (zh) | 2009-01-14 | 2012-09-05 | 首都医科大学宣武医院 | 一种脱除血管组织内细胞的血管基质及其制备方法 |
EP3545980A1 (en) * | 2010-02-26 | 2019-10-02 | DeCell Technologies Inc. | Methods for tissue decellularization |
-
2011
- 2011-09-26 PL PL11764272T patent/PL2621548T3/pl unknown
- 2011-09-26 WO PCT/GB2011/051817 patent/WO2012042250A1/en active Application Filing
- 2011-09-26 BR BR112013005278-3A patent/BR112013005278B1/pt not_active IP Right Cessation
- 2011-09-26 EP EP11764272.8A patent/EP2621548B1/en active Active
- 2011-09-26 CN CN201180046352.5A patent/CN103124570B/zh active Active
- 2011-09-26 AU AU2011309900A patent/AU2011309900B2/en not_active Ceased
- 2011-09-26 JP JP2013529715A patent/JP5881711B2/ja not_active Expired - Fee Related
- 2011-09-26 US US13/876,429 patent/US9510933B2/en not_active Expired - Fee Related
- 2011-09-26 ES ES11764272.8T patent/ES2628441T3/es active Active
- 2011-09-26 CA CA2808478A patent/CA2808478C/en active Active
-
2013
- 2013-11-15 HK HK13112846.6A patent/HK1185292A1/xx not_active IP Right Cessation
-
2014
- 2014-06-25 AU AU2014203460A patent/AU2014203460B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JP2013537828A (ja) | 2013-10-07 |
CN103124570A (zh) | 2013-05-29 |
ES2628441T3 (es) | 2017-08-02 |
EP2621548B1 (en) | 2017-05-24 |
AU2014203460A1 (en) | 2014-07-17 |
JP5881711B2 (ja) | 2016-03-09 |
AU2011309900A1 (en) | 2013-05-02 |
CA2808478C (en) | 2015-10-06 |
US20130197667A1 (en) | 2013-08-01 |
CN103124570B (zh) | 2015-04-22 |
US9510933B2 (en) | 2016-12-06 |
EP2621548A1 (en) | 2013-08-07 |
AU2014203460B2 (en) | 2016-04-14 |
PL2621548T3 (pl) | 2017-11-30 |
HK1185292A1 (en) | 2014-02-14 |
AU2011309900B2 (en) | 2014-07-24 |
CA2808478A1 (en) | 2012-04-05 |
WO2012042250A1 (en) | 2012-04-05 |
BR112013005278B1 (pt) | 2019-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112013005278A2 (pt) | produtos vasculares acelulares | |
PH12018500767A1 (en) | Pharmaceutical composition, methods for treating and uses thereof | |
MX2010005018A (es) | Tratamiento de complicaciones de nacimiento prematuro. | |
MX2013011835A (es) | Composiciones nutricionales que incluyen acidos grasos de cadena ramificada para la curacion de heridas. | |
AU2011338389A8 (en) | Bicyclic compounds as Pim inhibitors | |
BR112012028290A2 (pt) | desintoxicação de acetato derivado de biomassa via conversão metabólica em etanol, acetona, isopropanol ou acetato de etila | |
BR112015009473A2 (pt) | hidrolisado de colágeno e uso do mesmo | |
BR112013005679A2 (pt) | imidazopiridazinas substituídas | |
WO2012019168A3 (en) | Engineered nucleic acids and methods of use thereof | |
BR112016010175A2 (pt) | Repressor genético, seus usos, e composição farmacêutica | |
PH12016500478A1 (en) | Isolated strain of clonostachys rosea for use as a biological control agent | |
EA201490512A1 (ru) | Композиции, содержащие культивируемую в анаэробных условиях микробиоту кишечника человека | |
BR112012017690A2 (pt) | Emulsões nutricionais compreendendo hmb de cálcio | |
WO2013039861A3 (en) | Engineered nucleic acids and methods of use thereof | |
BR112016029713A8 (pt) | uso de uma carboximetilcelulose reticulada e uso de um agente gelificante | |
NZ595952A (en) | Antimicrobial compositions and related methods of use | |
NZ590343A (en) | Compositions monovalent for cd28 binding and methods of use | |
WO2012163869A3 (en) | Composition comprising an alkoxysilane and a modified starch, and cosmetic use thereof | |
BR112015017069A2 (pt) | processo para preparação de extrato a partir de meio de cultura de ceriporialacerata e composições farmacêuticas preparadas pelo que para prevenção ou tratamento de doenças diabéticas e complicações diabéticas, que contêm extrato de meio de cultura de ceriporialacerata como ingrediente ativo | |
EA201390826A1 (ru) | ПИРИМИДИНОНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ПРИМЕНЕНИЯ В ЛЕЧЕНИИ ЗАБОЛЕВАНИЙ ИЛИ СОСТОЯНИЙ, ОПОСРЕДОВАННЫХ Lp-PLA | |
MX2013012661A (es) | Compuestos de piridazina biciclicos como inhibidores pim. | |
BR112017012682A2 (pt) | processo para aperfeiçoamento de porções de músculo e produtos | |
WO2012028335A3 (en) | Kinases as targets for anti-diabetic therapy | |
MY178445A (en) | Novel antibody binding to tfpi and composition comprising the same | |
NZ602317A (en) | Stabilized alpha-galactosidase and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: TISSUE REGENIX LIMITED (GB) |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/09/2011, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/09/2011, OBSERVADAS AS CONDICOES LEGAIS |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 10A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2640 DE 10-08-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |