BR112013001462A2 - composições de ciclopolissacarídeos aniônico-catiônicos de bendamustina - Google Patents
composições de ciclopolissacarídeos aniônico-catiônicos de bendamustinaInfo
- Publication number
- BR112013001462A2 BR112013001462A2 BR112013001462A BR112013001462A BR112013001462A2 BR 112013001462 A2 BR112013001462 A2 BR 112013001462A2 BR 112013001462 A BR112013001462 A BR 112013001462A BR 112013001462 A BR112013001462 A BR 112013001462A BR 112013001462 A2 BR112013001462 A2 BR 112013001462A2
- Authority
- BR
- Brazil
- Prior art keywords
- bendamustine
- anionic
- cationic
- cyclopolysaccharide
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39985510P | 2010-07-19 | 2010-07-19 | |
| US61/399,855 | 2010-07-19 | ||
| US13/032,168 | 2011-02-22 | ||
| US13/032,168 US8383663B2 (en) | 2010-07-19 | 2011-02-22 | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
| PCT/IB2011/003367 WO2012127277A2 (en) | 2010-07-19 | 2011-02-23 | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112013001462A2 true BR112013001462A2 (pt) | 2016-05-31 |
| BR112013001462B1 BR112013001462B1 (pt) | 2022-04-19 |
| BR112013001462B8 BR112013001462B8 (pt) | 2022-08-02 |
Family
ID=45467434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013001462A BR112013001462B8 (pt) | 2010-07-19 | 2011-02-23 | Composições |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8383663B2 (pt) |
| EP (1) | EP2595660B1 (pt) |
| JP (1) | JP5788982B2 (pt) |
| KR (2) | KR101874764B1 (pt) |
| CN (1) | CN103228296B (pt) |
| AU (3) | AU2011363446B2 (pt) |
| BR (1) | BR112013001462B8 (pt) |
| CA (1) | CA2805805C (pt) |
| MX (1) | MX341356B (pt) |
| RU (1) | RU2647368C2 (pt) |
| WO (1) | WO2012127277A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108997514B (zh) * | 2017-06-06 | 2021-06-08 | 首都医科大学 | 单-6-(苯达莫司汀酰胺基)-6-脱氧-β-环糊精的制备和应用 |
| MX2020003511A (es) | 2017-10-05 | 2020-07-22 | Tube Pharmaceuticals Gmbh | Formulaciones orales de bendamustina. |
| CN111557904A (zh) * | 2020-04-09 | 2020-08-21 | 比卡生物科技（广州）有限公司 | 苯达莫司汀组合物及其用途 |
| WO2021203377A1 (zh) * | 2020-04-09 | 2021-10-14 | 比卡生物科技（广州）有限公司 | 苯达莫司汀组合物及其用途 |
| US11970977B2 (en) | 2022-08-26 | 2024-04-30 | Hamilton Sundstrand Corporation | Variable restriction of a secondary circuit of a fuel injector |
| US20240148696A1 (en) | 2022-10-25 | 2024-05-09 | Softkemo Pharma Inc. | Lyophilized bendamustine-cyclodextrin composition |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407079B1 (en) | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
| US5068226A (en) | 1987-12-07 | 1991-11-26 | Cyclex, Inc. | Pharmaceutical preparations containing cyclodextrins and their use in iontophoretic therapies |
| JPH04500229A (ja) * | 1988-08-31 | 1992-01-16 | オーストレイリアン・コマーシヤル・リサーチ・アンド・デイベロツプメント・リミテツド | 薬剤分配用及びクロマトグラフィー用の組成物及び方法 |
| MY106598A (en) | 1988-08-31 | 1995-06-30 | Australian Commercial Res & Development Ltd | Compositions and methods for drug delivery and chromatography. |
| US5602112A (en) | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
| KR100563764B1 (ko) | 1997-03-13 | 2006-03-24 | 헥살 아게 | 아미노산과 시클로덱스트린과의 병용에 의한 산(酸) 민감성 벤즈이미다졸류의 안정화 방법 |
| US6624141B1 (en) | 1999-03-17 | 2003-09-23 | The Regents Of The University Of Michigan | Protamine fragment compositions and methods of use |
| DK1165119T3 (da) | 1999-04-08 | 2003-12-15 | Genentech Inc | Sammensætning baseret på modsat ladede polypeptider |
| GB9921958D0 (en) | 1999-09-16 | 1999-11-17 | Pharmacia & Upjohn Spa | Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins |
| US20030044356A1 (en) | 2001-04-20 | 2003-03-06 | Jin Auh | Composition for nasal solution sprays having effective component of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one) |
| AR038576A1 (es) | 2002-02-22 | 2005-01-19 | Pharmacia Corp | Formulaciones de drogas antibioticas oftalmicas que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio |
| CN1646171B (zh) | 2002-04-19 | 2010-05-26 | 诺瓦提斯公司 | 新型生物材料、其制备和用途 |
| RU2342931C2 (ru) * | 2002-08-20 | 2009-01-10 | Бристол-Маерс Сквибб Компани | Состав на основе комплекса арипипразола |
| ATE513858T1 (de) * | 2004-09-10 | 2011-07-15 | Nat Ct For Scient Res Sdemokritoss Neapoleos & | Per-6-guanidino-, -aminoalkylamino- und - guanidino-alkylamino-cyclodextrine, verfahren zu ihrer synthese und ihre verwendung zur kompaktierung von dna und interazellulären zuführung |
| CA2585659A1 (en) * | 2004-11-05 | 2006-06-22 | Cephalon, Inc. | Cancer treatments |
| CN101052396A (zh) * | 2004-11-05 | 2007-10-10 | 赛福伦公司 | 癌症治疗 |
| US20060128653A1 (en) * | 2004-12-10 | 2006-06-15 | Chunlin Tang | Pharmaceutical formulation of decitabine |
| US8436190B2 (en) | 2005-01-14 | 2013-05-07 | Cephalon, Inc. | Bendamustine pharmaceutical compositions |
| WO2006083671A2 (en) | 2005-01-28 | 2006-08-10 | Brigham Young University | Bacterial glycolipid activation of cd1d-restricted nkt cells |
| EP1760467A1 (en) | 2005-09-02 | 2007-03-07 | Schering AG | Optically fluorescent nanoparticles |
| CN1846685A (zh) | 2006-01-25 | 2006-10-18 | 济南帅华医药科技有限公司 | 含苯达莫司汀和其增效剂的缓释注射剂 |
| US8372834B2 (en) | 2007-03-02 | 2013-02-12 | University Of Wollongong | Compositions and methods for delivery of anti-cancer agents |
| CN101219113A (zh) | 2008-01-28 | 2008-07-16 | 济南帅华医药科技有限公司 | 含苯达莫司汀的复方抗癌缓释注射剂 |
| CN102164579B (zh) * | 2008-09-25 | 2014-10-15 | 赛福伦公司 | 苯达莫司汀的液体配制品 |
| RU2734236C2 (ru) | 2009-02-25 | 2020-10-13 | Софткемо Фарма Корп. | Композиции бендамустина и циклополисахарида |
| CN101606934B (zh) | 2009-07-27 | 2011-09-28 | 江苏奥赛康药业有限公司 | 盐酸苯达莫司汀组合物 |
| WO2011103150A2 (en) | 2010-02-18 | 2011-08-25 | Cephalon, Inc. | Lyophilized preparations of bendamustine |
| CN101897977A (zh) | 2010-07-29 | 2010-12-01 | 浙江大学 | 离子型环糊精衍生物在制备用于离子导入透皮给药的药物制剂中的应用 |
-
2011
- 2011-02-22 US US13/032,168 patent/US8383663B2/en active Active
- 2011-02-23 CN CN201180044724.0A patent/CN103228296B/zh active Active
- 2011-02-23 KR KR1020177023950A patent/KR101874764B1/ko active IP Right Grant
- 2011-02-23 RU RU2013107115A patent/RU2647368C2/ru not_active Application Discontinuation
- 2011-02-23 CA CA2805805A patent/CA2805805C/en active Active
- 2011-02-23 AU AU2011363446A patent/AU2011363446B2/en active Active
- 2011-02-23 EP EP11861891.7A patent/EP2595660B1/en active Active
- 2011-02-23 MX MX2013000729A patent/MX341356B/es active IP Right Grant
- 2011-02-23 KR KR1020137004170A patent/KR101807903B1/ko active IP Right Grant
- 2011-02-23 BR BR112013001462A patent/BR112013001462B8/pt active IP Right Grant
- 2011-02-23 WO PCT/IB2011/003367 patent/WO2012127277A2/en active Application Filing
- 2011-02-23 JP JP2013520244A patent/JP5788982B2/ja active Active
-
2017
- 2017-08-18 AU AU2017216568A patent/AU2017216568A1/en not_active Abandoned
-
2019
- 2019-08-21 AU AU2019219792A patent/AU2019219792B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2805805C (en) | 2018-10-23 |
| CN103228296B (zh) | 2015-04-08 |
| AU2019219792A1 (en) | 2019-09-12 |
| WO2012127277A3 (en) | 2013-03-14 |
| RU2647368C2 (ru) | 2018-03-15 |
| AU2019219792B2 (en) | 2023-03-02 |
| US8383663B2 (en) | 2013-02-26 |
| KR101807903B1 (ko) | 2017-12-12 |
| CN103228296A (zh) | 2013-07-31 |
| BR112013001462B8 (pt) | 2022-08-02 |
| BR112013001462B1 (pt) | 2022-04-19 |
| KR20170102061A (ko) | 2017-09-06 |
| RU2013107115A (ru) | 2014-08-27 |
| KR20130113428A (ko) | 2013-10-15 |
| US20120015995A1 (en) | 2012-01-19 |
| CA2805805A1 (en) | 2012-09-27 |
| EP2595660A2 (en) | 2013-05-29 |
| AU2017216568A1 (en) | 2017-09-14 |
| MX2013000729A (es) | 2013-07-17 |
| AU2011363446A1 (en) | 2013-02-21 |
| AU2011363446B2 (en) | 2017-05-18 |
| JP5788982B2 (ja) | 2015-10-07 |
| KR101874764B1 (ko) | 2018-07-04 |
| MX341356B (es) | 2016-07-07 |
| WO2012127277A2 (en) | 2012-09-27 |
| JP2013531060A (ja) | 2013-08-01 |
| EP2595660B1 (en) | 2015-07-22 |
| EP2595660A4 (en) | 2014-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SMT201700043B (it) | Formulazioni di bendamustina | |
| SMT201600350B (it) | Composizioni farmaceutiche | |
| DK2640893T4 (da) | Sammensætninger | |
| BR112012028556A2 (pt) | Indóis | |
| DE102011100241A8 (de) | Nitridhalbleiterbauteil | |
| CR20130111A (es) | Triazina-oxidiazoles | |
| DE10170954T8 (de) | Mikrowellendruckgarer | |
| DE112011104226A5 (de) | Käfigmutter | |
| DK3095817T3 (da) | Mikrogelsammensætninger | |
| DE102011117046A8 (de) | Doppelkupplungswindungsgetriebe | |
| DE112011101226A5 (de) | Linearwegmesssystem | |
| DE112011102080A5 (de) | Kupplungszentralausrücker | |
| DK2442899T3 (da) | Rotorskive | |
| DE102011002623A8 (de) | Ventilsteuerzeitversteller | |
| CO6801722A2 (es) | Composiciones farmacéuticas | |
| DE112011102711A5 (de) | Hydrostataktor | |
| DE102010019119B8 (de) | Cuttermesser | |
| DE112010005518A5 (de) | Dichtungsmanchette | |
| DE102010038420A8 (de) | Reinigungungsvorrichtung | |
| BR112013001462A2 (pt) | composições de ciclopolissacarídeos aniônico-catiônicos de bendamustina | |
| CO6801789A2 (es) | N-hetarilmetil pirazolilcarboxamidas | |
| DE112011101796A5 (de) | Redoxakkumulatoranlage | |
| DE102010035554B8 (de) | Fußtüröffner | |
| FI20105815A (fi) | Viilunpaikkauslaitteisto | |
| DK2404809T3 (da) | Trækbjælke |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B15I | Others concerning applications: loss of priority |
Free format text: PERDA DAS PRIORIDADES US 61/399855 DE 19/07/2010 E US 13/032168 DE 22/02/2011, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O E NO ART. 28 DO ATO NORMATIVO 128/1997, POR NAO ATENDER AO DISPOSTO NO ART. 27 DO ATO NORMATIVO 128/1997, POIS NAO FOI APRESENTADA CESSAO DA REFERIDA PRIORIDADE, QUE POSSUI DEPOSITANTE DIFERENTE DO DEPOSITANTE DA FASE NACIONAL. |
|
| B12F | Other appeals [chapter 12.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021 |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/02/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |
|
| B25A | Requested transfer of rights approved |
Owner name: SOFTKEMO PHARMA CORP. (CA) |