BR112012015433B8 - composição farmacêutica substancialmente anidra para aplicação cutânea - Google Patents
composição farmacêutica substancialmente anidra para aplicação cutânea Download PDFInfo
- Publication number
- BR112012015433B8 BR112012015433B8 BR112012015433A BR112012015433A BR112012015433B8 BR 112012015433 B8 BR112012015433 B8 BR 112012015433B8 BR 112012015433 A BR112012015433 A BR 112012015433A BR 112012015433 A BR112012015433 A BR 112012015433A BR 112012015433 B8 BR112012015433 B8 BR 112012015433B8
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- substantially anhydrous
- anhydrous pharmaceutical
- cutaneous application
- cutaneous
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
composição farmacêutica substancialmente anidra para aplicação cutânea é descrita uma composição farmacêutica compreendendo um derivado ou análogo de vitamina d como o ingrediente ativo dissolvido em uma mistura de solvente do agente tensoativo de três componentes é usada no tratamento de distúrbios ou condições dérmicas.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK2009000265 | 2009-12-22 | ||
DKPCT/DK009/000256 | 2009-12-22 | ||
US29310510P | 2010-01-07 | 2010-01-07 | |
US61/293105 | 2010-01-07 | ||
PCT/DK2010/000182 WO2011076207A2 (en) | 2009-12-22 | 2010-12-22 | Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112012015433A2 BR112012015433A2 (pt) | 2016-03-15 |
BR112012015433B1 BR112012015433B1 (pt) | 2019-04-24 |
BR112012015433B8 true BR112012015433B8 (pt) | 2020-03-03 |
Family
ID=43618132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012015433A BR112012015433B8 (pt) | 2009-12-22 | 2010-12-22 | composição farmacêutica substancialmente anidra para aplicação cutânea |
Country Status (14)
Country | Link |
---|---|
US (2) | US20120322776A1 (pt) |
EP (1) | EP2515865B1 (pt) |
JP (1) | JP5873439B2 (pt) |
CN (1) | CN102781425B (pt) |
AU (1) | AU2010335654B2 (pt) |
BR (1) | BR112012015433B8 (pt) |
CA (1) | CA2785251A1 (pt) |
HK (1) | HK1177899A1 (pt) |
IL (1) | IL220514A (pt) |
MX (1) | MX2012007229A (pt) |
NZ (1) | NZ600999A (pt) |
RU (1) | RU2560677C2 (pt) |
WO (1) | WO2011076207A2 (pt) |
ZA (1) | ZA201204620B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5570442B2 (ja) * | 2011-01-24 | 2014-08-13 | 株式会社シャネル化粧品技術開発研究所 | 水中油型乳化組成物及びその製造方法 |
JP6367819B2 (ja) * | 2012-11-30 | 2018-08-01 | レオ ファーマ アクティーゼルスカブ | 活性化t細胞におけるil−22の発現の阻害方法 |
CN105899950B (zh) * | 2013-12-19 | 2017-11-24 | 根特大学 | 鱼鳞中作为对于慢性应激的生物标记物的糖皮质激素的量化 |
CN104666312B (zh) * | 2015-02-12 | 2017-11-07 | 重庆华邦制药有限公司 | 含有卡泊三醇和二丙酸倍他米松的制剂 |
CN106265485A (zh) * | 2016-08-22 | 2017-01-04 | 江苏知原药业有限公司 | 一种稳定性改善的卡泊三醇组合物 |
CN106265511A (zh) * | 2016-08-22 | 2017-01-04 | 江苏知原药业有限公司 | 一种性能优异的卡泊三醇倍他米松自微乳制剂 |
CN106442841B (zh) * | 2016-12-16 | 2018-09-14 | 上海景峰制药有限公司 | 一种药物中阳离子表面活性剂的分离检测方法 |
US11433090B2 (en) | 2017-06-16 | 2022-09-06 | The Doshisha | mTOR-inhibitor-containing medicine for treating or preventing ophthalmic symptoms, disorders, or diseases, and application thereof |
EP3741378A1 (de) | 2019-05-23 | 2020-11-25 | Dimitrios Tsakouridis | Zusammensetzung zur topischen behandlung und pflege der psoriatischen haut |
Family Cites Families (42)
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US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
JP2655190B2 (ja) * | 1989-06-21 | 1997-09-17 | エスエス製薬 株式会社 | コルチコステロイド含有軟膏剤 |
ZA925581B (en) * | 1991-07-26 | 1993-05-14 | Smithkline Beecham Corp | Pharmaceutical microemulsions. |
US5766628A (en) * | 1992-02-24 | 1998-06-16 | Merz + Co. Gmbh & Co. | Bath and shower composition having vesicle-forming properties and method for the production and use thereof |
USRE39706E1 (en) | 1993-01-15 | 2007-06-26 | Leo Pharma A/S | Crystalline form of a vitamin D analogue |
DE69431310T2 (de) | 1993-04-19 | 2003-05-22 | Inst Advanced Skin Res Inc | Mikroemulsionszubereitung enthaltend eine schwer absorbierbare substanz |
GB9405304D0 (en) | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
GB9602111D0 (en) * | 1996-02-02 | 1996-04-03 | Unilever Plc | Personal care composition |
GB9611603D0 (en) * | 1996-06-04 | 1996-08-07 | Leo Pharm Prod Ltd | Chemical compounds |
FR2753377B1 (fr) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
US6432422B1 (en) * | 1997-12-09 | 2002-08-13 | Chugai Seiyaku Kabushiki Kaisha | Creams containing vitamin D3 derivatives |
US5989531A (en) * | 1998-11-13 | 1999-11-23 | Colgate-Palmolive Company | Antiperspirant formulation for porous applicator |
GB9903547D0 (en) * | 1999-02-16 | 1999-04-07 | Novartis Ag | Organic compounds |
US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6582683B2 (en) * | 2000-01-04 | 2003-06-24 | Skinvisible Pharmaceuticals, Inc. | Dermal barrier composition |
WO2006120681A2 (en) * | 2005-05-10 | 2006-11-16 | Dermipsor Ltd. | Compositions and methods for skin care |
EP1331927B1 (en) * | 2000-10-27 | 2007-12-12 | Leo Pharma A/S | Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid |
US7005557B2 (en) * | 2001-07-03 | 2006-02-28 | The Procter & Gamble Company | Film-forming compositions for protecting skin from body fluids and articles made therefrom |
IL164163A0 (en) * | 2002-04-09 | 2005-12-18 | Pharmacia Corp | Process for preparing a finely self-emulsifiable pharmaceutical composition |
US20060189586A1 (en) * | 2003-06-11 | 2006-08-24 | Cleland Jeffrey L | Pharmaceutical compositions comprising active vitamin D compounds |
JP4608615B2 (ja) * | 2003-06-17 | 2011-01-12 | コグニス・アイピー・マネジメント・ゲーエムベーハー | 皮膚引き締め用組成物中の変性大豆タンパク質 |
JP4939216B2 (ja) | 2003-07-24 | 2012-05-23 | レオ ファーマ アクティーゼルスカブ | 新規アミノベンゾフェノン化合物 |
US8795693B2 (en) * | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
US20090105336A1 (en) * | 2004-04-19 | 2009-04-23 | Strategic Science & Technologies, Llc | Beneficial Effects of Increasing Local Blood Flow |
WO2005123090A1 (en) * | 2004-06-17 | 2005-12-29 | Galderma S.A. | Composition in spray form comprising a combination of a corticoid and a vitamin d derivative in an oily phase |
FR2871694B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition pharmaceutique comprenant un onguent oleagineux et deux principes actifs solubilises |
DK1828148T3 (da) | 2004-12-13 | 2010-05-17 | Leo Pharma As | Triazolsubstituerede aminobenzophenonforbindelser |
EP1827297A1 (en) * | 2004-12-23 | 2007-09-05 | Unilever Plc | Water-in-oil emulsions for hair treatment |
WO2006138056A1 (en) * | 2005-06-15 | 2006-12-28 | Apollo Pharmaceutical, Inc. | Pharmaceutical composition comprising a mahonia aquifolium extract for the treatment of psoriasis |
FR2887150B1 (fr) * | 2005-06-17 | 2007-08-03 | Galderma Res & Dev | Composition pharmaceutique comprenant un elastomere organopolysiloxane et un principe actif solubilise |
US20070249055A1 (en) * | 2006-04-24 | 2007-10-25 | The Procter & Gamble Company | Method of measuring lotion and additive ingredient transfer |
US20080260655A1 (en) * | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
FR2909284B1 (fr) * | 2006-11-30 | 2012-09-21 | Galderma Sa | Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien |
MX2009006593A (es) | 2006-12-22 | 2009-07-02 | Leo Pharma As | Acetofenonas sustituidas utiles como inhibidores de fosfodiesterasa 4. |
MX2009009238A (es) | 2007-02-28 | 2009-09-08 | Leo Pharma As | Nuevos inhibidores de fosfodiesterasa. |
EP1970049A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D and corticosteroid |
CN101677979A (zh) | 2007-04-19 | 2010-03-24 | 利奥制药有限公司 | Src家族激酶抑制剂 |
KR101959952B1 (ko) * | 2007-04-25 | 2019-03-19 | 사이토크로마 인코포레이티드 | 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
WO2008141078A1 (en) | 2007-05-11 | 2008-11-20 | Sonneborn Inc. | Petrolatums having silicone-like properties |
US20080299156A1 (en) * | 2007-06-01 | 2008-12-04 | L'oreal | Skin care compositions containing a high internal phase emulsion |
MX2011006428A (es) | 2008-12-19 | 2011-07-28 | Leo Pharma As | Triazolopiridinas como inhibidores de fosfodiesterasa para tratamiento de enfermedades dermicas. |
JP2012531393A (ja) * | 2009-06-29 | 2012-12-10 | グラクソ グループ リミテッド | 新規の医学的使用 |
-
2010
- 2010-12-22 AU AU2010335654A patent/AU2010335654B2/en active Active
- 2010-12-22 US US13/518,320 patent/US20120322776A1/en not_active Abandoned
- 2010-12-22 CN CN201080063418.7A patent/CN102781425B/zh active Active
- 2010-12-22 CA CA2785251A patent/CA2785251A1/en not_active Abandoned
- 2010-12-22 BR BR112012015433A patent/BR112012015433B8/pt active IP Right Grant
- 2010-12-22 MX MX2012007229A patent/MX2012007229A/es active IP Right Grant
- 2010-12-22 RU RU2012130421/15A patent/RU2560677C2/ru active
- 2010-12-22 NZ NZ600999A patent/NZ600999A/en unknown
- 2010-12-22 WO PCT/DK2010/000182 patent/WO2011076207A2/en active Application Filing
- 2010-12-22 JP JP2012545090A patent/JP5873439B2/ja active Active
- 2010-12-22 EP EP10803218.6A patent/EP2515865B1/en active Active
-
2012
- 2012-06-19 IL IL220514A patent/IL220514A/en active IP Right Grant
- 2012-06-21 ZA ZA2012/04620A patent/ZA201204620B/en unknown
-
2013
- 2013-05-13 HK HK13105669.4A patent/HK1177899A1/xx unknown
-
2016
- 2016-07-19 US US15/214,216 patent/US20160324875A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR112012015433B1 (pt) | 2019-04-24 |
JP5873439B2 (ja) | 2016-03-01 |
RU2560677C2 (ru) | 2015-08-20 |
AU2010335654A1 (en) | 2012-07-26 |
CA2785251A1 (en) | 2011-06-30 |
JP2013515018A (ja) | 2013-05-02 |
CN102781425B (zh) | 2014-08-13 |
NZ600999A (en) | 2014-06-27 |
EP2515865B1 (en) | 2016-12-14 |
WO2011076207A3 (en) | 2012-03-01 |
CN102781425A (zh) | 2012-11-14 |
BR112012015433A2 (pt) | 2016-03-15 |
AU2010335654B2 (en) | 2015-04-09 |
MX2012007229A (es) | 2012-07-30 |
US20160324875A1 (en) | 2016-11-10 |
RU2012130421A (ru) | 2014-01-27 |
EP2515865A2 (en) | 2012-10-31 |
IL220514A (en) | 2017-01-31 |
WO2011076207A2 (en) | 2011-06-30 |
HK1177899A1 (en) | 2013-08-30 |
US20120322776A1 (en) | 2012-12-20 |
ZA201204620B (en) | 2013-09-25 |
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