BR112012015433A2 - composição farmacêutica substancialmente anidra para aplicação cutânea - Google Patents

composição farmacêutica substancialmente anidra para aplicação cutânea

Info

Publication number
BR112012015433A2
BR112012015433A2 BR112012015433A BR112012015433A BR112012015433A2 BR 112012015433 A2 BR112012015433 A2 BR 112012015433A2 BR 112012015433 A BR112012015433 A BR 112012015433A BR 112012015433 A BR112012015433 A BR 112012015433A BR 112012015433 A2 BR112012015433 A2 BR 112012015433A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
substantially anhydrous
anhydrous pharmaceutical
cutaneous application
cutaneous
Prior art date
Application number
BR112012015433A
Other languages
English (en)
Other versions
BR112012015433B8 (pt
BR112012015433B1 (pt
Inventor
Karsten Petersson
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of BR112012015433A2 publication Critical patent/BR112012015433A2/pt
Publication of BR112012015433B1 publication Critical patent/BR112012015433B1/pt
Publication of BR112012015433B8 publication Critical patent/BR112012015433B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

composição farmacêutica substancialmente anidra para aplicação cutânea é descrita uma composição farmacêutica compreendendo um derivado ou análogo de vitamina d como o ingrediente ativo dissolvido em uma mistura de solvente do agente tensoativo de três componentes é usada no tratamento de distúrbios ou condições dérmicas.
BR112012015433A 2009-12-22 2010-12-22 composição farmacêutica substancialmente anidra para aplicação cutânea BR112012015433B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPCT/DK009/000256 2009-12-22
DK2009000265 2009-12-22
US29310510P 2010-01-07 2010-01-07
US61/293105 2010-01-07
PCT/DK2010/000182 WO2011076207A2 (en) 2009-12-22 2010-12-22 Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants

Publications (3)

Publication Number Publication Date
BR112012015433A2 true BR112012015433A2 (pt) 2016-03-15
BR112012015433B1 BR112012015433B1 (pt) 2019-04-24
BR112012015433B8 BR112012015433B8 (pt) 2020-03-03

Family

ID=43618132

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012015433A BR112012015433B8 (pt) 2009-12-22 2010-12-22 composição farmacêutica substancialmente anidra para aplicação cutânea

Country Status (14)

Country Link
US (2) US20120322776A1 (pt)
EP (1) EP2515865B1 (pt)
JP (1) JP5873439B2 (pt)
CN (1) CN102781425B (pt)
AU (1) AU2010335654B2 (pt)
BR (1) BR112012015433B8 (pt)
CA (1) CA2785251A1 (pt)
HK (1) HK1177899A1 (pt)
IL (1) IL220514A (pt)
MX (1) MX2012007229A (pt)
NZ (1) NZ600999A (pt)
RU (1) RU2560677C2 (pt)
WO (1) WO2011076207A2 (pt)
ZA (1) ZA201204620B (pt)

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JP5570442B2 (ja) * 2011-01-24 2014-08-13 株式会社シャネル化粧品技術開発研究所 水中油型乳化組成物及びその製造方法
JP6367819B2 (ja) 2012-11-30 2018-08-01 レオ ファーマ アクティーゼルスカブ 活性化ｔ細胞におけるｉｌ−２２の発現の阻害方法
AU2014368789B2 (en) * 2013-12-19 2020-04-16 Instituut Voor Landbouw- En Visserijonderzoek (Ilvo) Quantification of glucocorticoids in fish scales as biomarkers for chronic stress
CN104666312B (zh) * 2015-02-12 2017-11-07 重庆华邦制药有限公司 含有卡泊三醇和二丙酸倍他米松的制剂
CN106265485A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种稳定性改善的卡泊三醇组合物
CN106265511A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种性能优异的卡泊三醇倍他米松自微乳制剂
CN106442841B (zh) * 2016-12-16 2018-09-14 上海景峰制药有限公司 一种药物中阳离子表面活性剂的分离检测方法
CA3067332A1 (en) 2017-06-16 2018-12-20 The Doshisha Mtor-inhibitor-containing medicine for treating or preventing ophthalmic symptoms, disorders, or diseases, and application thereof
EP3741378A1 (de) 2019-05-23 2020-11-25 Dimitrios Tsakouridis Zusammensetzung zur topischen behandlung und pflege der psoriatischen haut

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JP2655190B2 (ja) * 1989-06-21 1997-09-17 エスエス製薬 株式会社 コルチコステロイド含有軟膏剤
ATE144137T1 (de) * 1991-07-26 1996-11-15 Smithkline Beecham Corp W/o mikroemulsionen
US5766628A (en) * 1992-02-24 1998-06-16 Merz + Co. Gmbh & Co. Bath and shower composition having vesicle-forming properties and method for the production and use thereof
US5763426A (en) 1993-01-15 1998-06-09 Leo Pharmaceutical Products Ltd. Crystalline form of a vitamin D analogue
ES2182841T3 (es) 1993-04-19 2003-03-16 Inst Advanced Skin Res Inc Preparacion en microemulsion conteniendo una substancia dificilmente absorbible.
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
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Also Published As

Publication number Publication date
US20120322776A1 (en) 2012-12-20
BR112012015433B8 (pt) 2020-03-03
ZA201204620B (en) 2013-09-25
RU2560677C2 (ru) 2015-08-20
JP2013515018A (ja) 2013-05-02
RU2012130421A (ru) 2014-01-27
CN102781425B (zh) 2014-08-13
EP2515865B1 (en) 2016-12-14
CA2785251A1 (en) 2011-06-30
HK1177899A1 (en) 2013-08-30
BR112012015433B1 (pt) 2019-04-24
MX2012007229A (es) 2012-07-30
AU2010335654B2 (en) 2015-04-09
JP5873439B2 (ja) 2016-03-01
WO2011076207A2 (en) 2011-06-30
AU2010335654A1 (en) 2012-07-26
EP2515865A2 (en) 2012-10-31
US20160324875A1 (en) 2016-11-10
NZ600999A (en) 2014-06-27
WO2011076207A3 (en) 2012-03-01
IL220514A (en) 2017-01-31
CN102781425A (zh) 2012-11-14

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/12/2010, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/12/2010, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant

Free format text: REF. RPI 2520 DE 25/04/2019 QUANTO A PRIORIDADE UNIONISTA.